SOLID STATE ANTIMICROBIAL COMPOSITIONS AND METHODS FOR PRODUCING AND USING SAME
The present invention relates to antimicrobial, disinfecting, and wound healing compositions and methods for producing and using the same. The compositions may contain a peroxyacid, a hydroperoxide, the parent carboxylic acid of the peroxyacid, and a salt.
1 . A solid state antimicrobial composition comprising
a peroxyacid, a hydroperoxide, the parent carboxylic acid of the peroxyacid, and a salt selected from the group consisting of a lithium salt, a sodium salt, a potassium salt, a rubidium salt, a cesium salt, a zinc salt, a magnesium salt, a calcium salt and a combination thereof.
2 . The composition of claim 1 , wherein the hydroperoxide is hydrogen peroxide.
3 . The composition of claim 1 , wherein the salt is a magnesium salt.
4 . The composition of claim 3 , wherein the magnesium salt is selected from the group consisting of a magnesium oxide, magnesium hydroxide, magnesium carbonate, magnesium acetate tetrahydrate, and a combination thereof.
5 . The composition of claim 3 , wherein the magnesium salt is magnesium acetate tetrahydrate.
6 . The composition of claim 1 , wherein the peroxyacid is peracetic acid.
7 . The composition of claim 1 , wherein the peroxyacid comprises a magnesium salt of the peroxyacid.
8 . The composition of claim 1 , wherein the composition further comprises at least one of a bis(hydroperoxide) or an epoxide.
9 . The composition of claim 8 , wherein the peroxyacid is peracetic acid and the bis(hydroperoxide) is 3,3-bis(hydroperoxy)butanoic acid.
10 . The composition of claim 1 formulated as a wound healing composition.
11 . The composition of claim 1 , wherein the wound healing composition is formulated as a gel, a liquid, lotion, skin patch, irrigation gel, a spray, application granules, or a combination thereof for healing wounds.
12 . A method for treating a wound infection in a subject comprising contacting the infected wound in the subject with a therapeutically effective amount of the composition of claim 10 .
13 . The method of claim 12 , wherein the infected wound is a surgical wound, battle wound, accidental wound, thermal burn wound, chemical burn wound, chronic wound, decubitus ulcer, foot ulcer, venous ulcer, laser treatment wound, sunburn, or an abrasion.
14 . The method of claim 12 , wherein the infected wound is contacted with the composition once a day.
15 . The method of claim 12 , wherein the composition is formulated as a gel, a liquid, lotion, skin patch, irrigation gel, a spray, application granules, or a combination thereof.