IP Library Granted Patent US 12,433,242
Granted Patent B2
US 12,433,242 · App. 17/792,682 · Granted Oct 7, 2025

Devices, systems, and methods for introducing organisms into populations

Inventors: Kevin M. Esvelt (Cambridge, MA); Sarah Anna Vitak (Cambridge, MA)
Assignee: Massachusetts Institute of Technology
A01K1/031A01K1/0017A01K21/00A01K29/005
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Quick Facts
Patent No.
US 12,433,242
App. No.
17/792,682
Granted
Oct 7, 2025
Kind
B2
Abstract

The invention relates, in part, to devices, systems and methods to increase the likelihood of survival and reproductive success of preselected organisms. An organism container may be configured for permitting access to a preselected organism and denying access to other organisms. The container may include a floor, one or more walls, a door, a lock associated with the door, and a first sensor configured to unlock the lock to selectively move the door into the open configuration when it detects the presence of the preselected organism at the door and outside of the organism enclosure so the preselected organism can enter the container cavity, and the first sensor is configured to prevent access to the container cavity to other organisms.

Claims (41)

1. An organism container configured for permitting access to a preselected organism and denying access to other organisms, the organism container comprising:

an organism enclosure which includes a floor, and one or more walls, which together define a container cavity configured to hold one or more of the organism;

a door configured for selective access of one or more of the preselected organisms into the container cavity, wherein the door has an open configuration configured to permit entry of one or more of the preselected organism into the container cavity, and a closed configuration configured to deny entry of other of the organisms into the container cavity;

a lock associated with the door, wherein the lock is configured to keep the door in the closed configuration;

a first sensor associated with the organism enclosure, wherein the first sensor is configured to unlock the lock to selectively move the door into the open configuration when the first sensor detects the presence of the preselected organism at the door and outside of the organism enclosure so the preselected organism can enter the container cavity, and wherein the first sensor is configured to prevent access to the container cavity to other organisms;

a second sensor associated with the organism enclosure, wherein the second sensor is configured to unlock the lock to selectively move the door into the open configuration when the second sensor detects the presence of the preselected organism at the door and inside of the organism enclosure so that the preselected organism can exit the container cavity; and

a panel positioned above the door, wherein the first sensor is positioned on a first end of the panel, and the second sensor is positioned on a second end of the panel.

2. The organism container of claim 1 , wherein the first sensor is a magnetic sensor.

3. The organism container of claim 1 , wherein the first sensor is an RFID sensor.

4. The organism container of claim 1 , wherein the door is configured to move back into the closed configuration after the presence of the preselected organism at the door is not detected at the first sensor for at least approximately 5, 10, 15, 20, 25, or 30 seconds.

5. The organism container of claim 1 , in combination with an identification element configured to be in or on a preselected organism, wherein the identification element is configured to interact with the first sensor and the second sensor to detect the presence of the preselected organism.

6. The organism container of claim 1 , wherein the preselected organism is a rodent, and optionally is pregnant.

7. The organism container of claim 1 , wherein the preselected organism is a genetically engineered organism.

8. The organism container of claim 1 , in combination with an identification element configured to be in or on the preselected organism, wherein the identification element is configured to interact with the first sensor to detect the presence of the preselected organism, and optionally, wherein the container further comprises one or more of a remotely controlled element and a programmable element capable of opening or closing the organism container door independent of the presence of the identification element of the preselected organism.

9. A system configured for introducing a preselected organism into a habitat and denying access to the system to other organisms, the system comprising:

an organism container, the container comprising:

an organism enclosure which includes a floor, and one or more walls which together define a container cavity configured to hold one or more of a preselected organism;

a door configured for selective access of one or more of the organisms into the container cavity, wherein the door has an open configuration configured to permit entry of one or more organisms into the container cavity, and a closed configuration configured to deny entry of other organisms into the container cavity;

a lock associated with the door, wherein the lock is configured to keep the door in the closed configuration;

a first sensor associated with the organism enclosure, wherein the first sensor is configured to unlock the lock to selectively move the door into the open configuration when the first sensor detects the presence of the preselected organism at the door and outside of the organism enclosure so that the preselected organism can enter the container cavity, and wherein the first sensor is configured to prevent access to the container cavity to other organisms;

an identification element configured to be in or on the preselected organism, wherein the identification element is configured to interact with the first sensor to detect the presence of the preselected organism;

a second sensor associated with the organism enclosure, wherein the second sensor is configured to unlock the lock to selectively move the door into the open configuration when the second sensor detects the presence of the preselected organism at the door and inside of the organism enclosure so that the preselected organism can exit the container cavity;

wherein the identification element is configured to interact with the second sensor to detect the presence of the preselected organism; and

a panel positioned above the door, wherein the first sensor is positioned on a first end of the panel, and the second sensor is positioned on a second end of the panel.

10. The system of claim 9 , wherein the first sensor is a magnetic sensor.

11. The system of claim 9 , wherein the organism container further comprises one or more of a remotely controlled element and a programmable element capable of opening or closing the organism container door independent of the presence of the identification element of the preselected organism.

12. The system of claim 9 , wherein the habitat is a wild habitat, and optionally the wild habitat comprises a target population of organisms of the species of the preselected organism.

13. A method for introducing a preselected organism into a habitat and increasing likelihood of survival of the preselected organism, the method comprising:

providing an organism enclosure which defines a container cavity configured to hold one or more of an organism, the organism enclosure having a door configured for selective access of one or more of the organisms into the container cavity, wherein the door has an open configuration configured to permit entry of one or more of a preselected organism into the container cavity, and a closed configuration configured to deny entry of other organisms into the container cavity;

providing a first sensor on a first end of a panel positioned above the door, wherein the first sensor is configured to prevent access to the container cavity to other organisms;

placing the organism enclosure and the preselected organisms into the habitat, wherein the habitat includes other organisms;

moving the door into the open configuration when the first sensor detects the presence of the preselected organism at the door and outside of the organism enclosure so that the preselected organism can enter the container cavity, and other organisms cannot enter the container cavity;

providing a second sensor on a second end of the panel positioned above the door; and

moving the door into the open configuration when the second sensor detects the presence of the preselected organism at the door and inside of the organism enclosure so the preselected organism can exit the container cavity and, wherein the method further comprises moving the door into the closed configuration when the second sensor does not detect the presence of the preselected organism at the door; and locking the door in the closed configuration.

14. The method of claim 13 , further comprising;

moving the door into the closed configuration when the first sensor does not detect the presence of the preselected organism at the door; and

locking the door in the closed configuration.

15. The method of claim 13 , further comprising:

providing the preselected organism with an identification element, wherein the identification element is configured to interact with the first sensor and the second sensor to detect the presence of the preselected organism.

16. The method of claim 13 , wherein the preselected organism is an engineered organism, optionally the preselected organism is a rodent, and optionally the preselected organism is pregnant, and wherein the other organisms are non-engineered organisms.

17. The method of claim 13 , wherein the habitat is a wild habitat, and optionally the wild habitat comprises a target population of organisms of the species of the preselected organism.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 14, 2022
From: ESVELT, KEVIN M.; VITAK, SARAH ANNA
To: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Reel/Frame 061421/0105 →
Continuity (2)
Provisional Application 62961020 · Jan 14, 2020
Related Publication 20230039625A1 · Feb 9, 2023
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