WO WO2010025267
· 2010
[cited by applicant]
WO WO2016072936
· 2016
[cited by applicant]
WO WO2016210373
· 2016
[cited by applicant]
WO WO2018237198
· 2018
[cited by applicant]
WO WO2019055781
· 2019
[cited by applicant]
Palmer et al., “Microcin H47: A Class IIb Microcin with Potent Activity Against Multidrug Resistant Enterobacteriaceae”, ACS Infect. Dis. 6:672-679, 2020 (Year: 2020).
[cited by examiner]
Vassiliadis G, Destoumieux-Garzón DLombard C, Rebuffat S, Peduzzi J. (2010). Isolation and Characterization of Two Members of the Siderophore-Microcin Family, Microcins M and H47. Antimicrob Agents Chemother 54, No. 1.
[cited by examiner]
Thomas et al. (The Journal of Biological Chemistry. Vol. 279, No. 27, Issue of Jul. 2, 2004; pp. 28233-28242).
[cited by examiner]
Azpiroz et al., “Microcin H47 system: an
[cited by applicant]
Azpiroz et al., “Microcins and urovirulence in
[cited by applicant]
Bayro et al., “Structure of antibacterial peptide microcin J25: a 21-residue lariat protoknot,” Journal of the American Chemical Society, Oct. 13, 2003, 125(41):12382-3.
[cited by applicant]
Bucci et al., “The evolution of bacteriocin production in bacterial biofilms,” The American Naturalist, Dec. 1, 2011, 178(6):E162-73.
[cited by applicant]
Chatham-Stephens et al., “Emergence of extensively drug-resistant
[cited by applicant]
Daeffler et al., “Engineering bacterial thiosulfate and tetrathionate sensors for detecting gut inflammation,” Molecular Systems Biology, Apr. 2017, 13(4):923, 13 pages.
[cited by applicant]
David et al., “Epidemic of carbapenem-resistant Klebsiella pneumoniae in Europe is driven by nosocomial spread,” Nature Microbiology, Nov. 2019, 4(11):1919-29.
[cited by applicant]
Delgado et al., “YojI of
[cited by applicant]
Duquesne et al., “Microcins, gene-encoded antibacterial peptides from enterobacteria,” Natural Product Reports, 2007, 24(4):708-34.
[cited by applicant]
EP European Search Report in European Appln. No. 18856596.4, dated Aug. 7, 2020, 17 pages.
[cited by applicant]
EP European Search Report in European Appln. No. 20802507.2, dated Jun. 15, 2022, 9 pages.
[cited by applicant]
EP Extended European Search Report in European Appln. No. 18856596.4, dated Nov. 10, 2020, 15 pages.
[cited by applicant]
Fomenko et al., “Regulation of microcin C51 operon expression: the role of global regulators of transcription,” Research in Microbiology, Jun. 1, 2001, 152(5):469-79.
[cited by applicant]
Geldart et al., “pMPES: a modular peptide expression system for the delivery of antimicrobial peptides to the site of gastrointestinal infections using probiotics,” Pharmaceuticals, Dec. 2016, 9(4):60, 16 pages.
[cited by applicant]
Geldart et al., “pMPES: a modular peptide expression system for the delivery of antimicrobial peptides to the site of gastrointestinal infections using probiotics,” Pharmaceuticals, Oct. 2, 2016, 9(4):60, 16 pages.
[cited by applicant]
Gibson et al., “Enzymatic assembly of DNA molecules up to several hundred kilobases,” Nature Methods, May 2009, 6(5):343-5.
[cited by applicant]
Landry et al., “Engineering diagnostic and therapeutic gut bacteria,” Microbiology Spectrum, Oct. 2017, 5(5), 22 pages.
[cited by applicant]
Medina et al., “Tackling threats and future problems of multidrug-resistant bacteria,” How to Overcome the Antibiotic Crisis, 2016, 3-33.
[cited by applicant]
Mercado et al., “The production in vivo of microcin E492 with antibacterial activity depends on salmochelin and EntF,” Journal of Bacteriology, Aug. 1, 2008, 190(15):5464-71.
[cited by applicant]
Metelev et al., “Structure of microcin B-like compounds produced by Pseudomonas syringae and species specificity of their antibacterial action, ” Journal of Bacteriology, Sep. 15, 2013, 195(18):4129-37.
[cited by applicant]
Mortzfeld et al., “MccI47 selectively inhibits enteric bacteria and reduces carbapenem-resistant Klebsiella pneumoniae colonization in vivo when administered via an engineered live biotherapeutic,” bioRxiv, Jan. 1, 2021…
[cited by applicant]
Nadell et al., “Cutting through the complexity of cell collectives. Proceedings of the Royal Society B: Biological Sciences,” Mar. 22, 2013, 280, 11 pages.
[cited by applicant]
Ng et al., “Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens,” Nature, Oct. 2013, 502(7469):96-9.
[cited by applicant]
Nolan et al., “Biosynthetic tailoring of microcin E492m: post-translational modification affords an antibacterial siderophore-peptide conjugate,” Journal of the American Chemical Society, Nov. 21, 2007, 129(46):14336-47.
[cited by applicant]
Nolan et al., “Investigations of the MceIJ-catalyzed posttranslational modification of the microcin E492 C-terminus: linkage of ribosomal and nonribosomal peptides to form “trojan horse” antibiotics,” Biochemistry, Sep.…
[cited by applicant]
Palmer et al., “Engineered probiotic for the inhibition of Salmonella via tetrathionate-induced production of microcin H47,” ACS Infectious Diseases, Jan. 12, 2018, 4(1):39-45.
[cited by applicant]
Patzer et al., “The colicin G, H and X determinants encode microcins M and H47, which might utilize the catecholate siderophore receptors FepA, Cir, Fiu and IroN,” Microbiology, Sep. 1, 2003, 149(9):2557-70.
[cited by applicant]
PCT International Preliminary Report on Patentability in International Appln. No. PCT/US2018/051079, dated Mar. 17, 2020, 9 pages.
[cited by applicant]
PCT International Preliminary Report on Patentability in International Appln. No. PCT/US2020/031182, dated Nov. 2, 2021, 6 pages.
[cited by applicant]
PCT International Preliminary Report on Patentability in International Appln. No. PCT/US2021/019225, dated Feb. 3, 2022, 11 pages.
[cited by applicant]
PCT International Search Report and Written Opinion in International Appln. No. PCT/U20S18/051079 dated Feb. 7, 2019, 13 pages.
[cited by applicant]
PCT International Search Report and Written Opinion in International Appln. No. PCT/US2020/031182, dated Aug. 18, 2020, 9 pages.
[cited by applicant]
PCT International Search Report and Written Opinion in International Appln. No. PCT/US2021/019225, dated Aug. 10, 2021, 11 pages.
[cited by applicant]
Poey et al., “Comparative analysis of chromosome-encoded microcins,” Antimicrobial Agents and Chemotherapy, Apr. 1, 2006, 50(4):1411-8.
[cited by applicant]
Poey et al., “Virulence profiles in uropathogenic
[cited by applicant]
Riglar et al., “Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation,” Nature Biotechnology, Jul. 2017, 35(7):653-8.
[cited by applicant]
Rodríguez et al., “The structural gene for microcin H47 encodes a peptide precursor with antibiotic activity,” Antimicrobial Agents and Chemotherapy, Sep. 1, 1999, 43(9):2176-82.
[cited by applicant]
Rojas et al., “Multidrug-Resistant Klebsiella pneumoniae ST307 in Traveler Returning from Puerto Rico to Dominican Republic,” Emerging Infectious Diseases, Aug. 2019, 25(8):1583-5.
[cited by applicant]
Sassone-Corsi et al.et al., Microcins Mediate Competition Among Enterobacteriaceae in the Inflamed Gut Naure; Dec. 8, 2016; vol. 540, 25 pages.
[cited by applicant]
Vassiliadis et al., “Isolation and characterization of two members of the siderophore-microcin family, microcins M and H47,” Antimicrobial Agents and Chemotherapy, Jan. 2010, 54(1):288-97.
[cited by applicant]
Winter et al., “Gut inflammation provides a respiratory electron acceptor for
[cited by applicant]
Winter et al., “Host-derived nitrate boosts growth of
[cited by applicant]
Bantysh et al., “Enzymatic synthesis of bioinformatically predicted microcin C-like compounds encoded by diverse bacteria,” Mbio, Jul. 2014, 5(3):10, 11 pages.
[cited by applicant]
EP Extended European Search Report in European Appln. No. 21760771.2, mailed on Mar. 14, 2024, 11 pages.
[cited by applicant]
Gaggero et al., “Genetic analysis of microcin H47 antibiotic system,” Journal of Bacteriology, Sep. 1993, 175(17):5420-7.
[cited by applicant]