IP Library Granted Patent US 11,878,040
Granted Patent B2
US 11,878,040 · App. 17/823,530 · Granted Jan 23, 2024

Compositions comprising probiotic and prebiotic components and mineral salts, with lactoferrin

Inventors: Valeria Longoni (Latina, IT); Marisa Penci (Latina, IT)
Assignee: GLAXOSMITHKLINE CONSUMER HEALTHCARE S.R.L.
A61K35/745A23L33/135A23L33/16A23L33/19A23L33/21A61K9/0095A61K31/733A61K35/747A61K36/064A61K38/063A61K38/40A61K47/02A61K47/20A61K47/26A61K47/36A61K47/42A23V2002/00A61K2035/11
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Quick Facts
Patent No.
US 11,878,040
App. No.
17/823,530
Granted
Jan 23, 2024
Kind
B2
Abstract

The present invention relates to compositions comprising probiotic and prebiotic components, mineral salts, lactoferrin, and possibly saccharomycetes, which perform correct, effective colonisation of the probiotic components administered, with enteric consequences which involve maintaining and/or restoring intestinal health and preventing the consequences of common dysbioses of the digestive tract caused by stress, incorrect dietary habits and antibiotic treatments. Said compositions also have a concomitant anti-inflammatory and immunomodulating action.

Claims (24)

1. A probiotic composition for oral administration comprising:

at least about 50 billion CFU/g Bifidobacterium longum R175;

at least about 150 billion CFU/g Lactobacillus helveticus R52;

at least about 150 billion CFU/g Lactobacillus plantarum R1012;

one or more prebiotic components selected from inulin, fructose, fructooligosaccharides and mixtures thereof;

one or more metal salts selected from the group consisting of magnesium gluconate, potassium citrate, copper citrate and zinc gluconate; and

one or more excipients.

2. The probiotic composition of claim 1 , further comprising glutathione.

3. A probiotic composition for oral administration comprising (a) probiotics in an amount of at least about: Bifidobacterium longum 50 billion CFU/g, Lactobacillus helveticus 150 billion CFU/g, and Lactobacillus plantarum 150 billion CFU/g, (b) one or more prebiotic components selected from inulin, fructose, fructooligosaccharides and mixtures thereof, (c) one or more metal salts selected from magnesium gluconate, potassium citrate, zinc gluconate, and copper citrate, and (e) excipients.

4. The probiotic composition of claim 3 , further comprising glutathione.

5. A probiotic composition for oral administration comprising

at least about 50 billion CFU/g Bifidobacterium longum;

at least about 150 billion CFU/g Lactobacillus helveticus;

at least about 150 billion CFU/g Lactobacillus plantarum;

a prebiotic component;

a mineral metal salt; and

an excipient.

6. The probiotic composition of claim 5 , wherein Bifidobacterium longum is Bifidobacterium longum R175.

7. The probiotic composition of claim 5 , wherein Lactobacillus helveticus is Lactobacillus helveticus R52.

8. The probiotic composition of claim 5 , wherein Lactobacillus plantarum is Lactobacillus plantarum R1012.

9. The probiotic composition of claim 5 , wherein the prebiotic component is selected from a group consisting of inulin, fructose, fructooligosaccharides, and any combination thereof.

10. The probiotic composition of claim 5 , wherein the mineral metal salt is selected from a group consisting of magnesium, potassium, copper, zinc, and any combination thereof.

11. The probiotic composition of claim 10 , wherein the magnesium salt is magnesium gluconate, the potassium salt is potassium citrate, the copper salt is copper citrate, and the zinc is zinc gluconate.

12. The probiotic composition of claim 5 , further comprising glutathione.

Assignments (5)
CHANGE OF NAME Recorded Apr 28, 2025
From: GLAXOSMITHKLINE CONSUMER HEALTHCARE S.R.L.
To: HALEON ITALY S.R.L.
Reel/Frame 070963/0282 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 29, 2023
From: WYETH LLC
To: PFIZER ITALIA S.R.L.
Reel/Frame 065070/0017 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 29, 2023
From: PFIZER ITALIA S.R.L.
To: PFIZER CONSUMER HEALTHCARE ITALY S.R.L.
Reel/Frame 065070/0078 →
MERGER AND CHANGE OF NAME Recorded Sep 29, 2023
From: PFIZER CONSUMER HEALTHCARE ITALY S.R.L.; GLAXOSMITHKLINE CONSUMER HEALTHCARE S.R.L.
To: GLAXOSMITHKLINE CONSUMER HEALTHCARE S.R.L.
Reel/Frame 065084/0013 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 29, 2023
From: LONGONI, VALERIA; PENCI, MARISA
To: WYETH LLC
Reel/Frame 065266/0280 →
Priority Claims (1)
IT MI2009A000019 · Jan 12, 2009 · national
Continuity (4)
Continuation 15485809 · Apr 12, 2017
Continuation 13179712 · Jul 11, 2011
Continuation In Part PCTUS2010020712 · Jan 12, 2010
Related Publication 20230045437A1 · Feb 9, 2023