Granted Patent
B2
US 12,734,034 · App. 17/830,012 · Granted Sep 15, 2026
Percutaneous heart valve delivery systems
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Abstract
Embodiments described herein address the need for improved catheter devices for delivery, repositioning and/or percutaneous retrieval of the percutaneously implanted heart valves. One embodiment employs a plurality of spring-loaded arms releasably engaged with a stent frame for controlling expansion for valve deployment. Another embodiment employs a plurality of filaments passing through a distal end of a pusher sleeve and apertures in a self-expandable stent frame to control its state of deployment. With additional features, lateral positioning of the stent frame may also be controlled. Yet another embodiment includes plurality of outwardly biased arms held to complimentary stent frame features by overlying sheath segments. Still another embodiment integrates a visualization system in the subject delivery system. Variations on hardware and methods associated with the use of these embodiments are contemplated in addition to those shown and described.
Claims (14)
1 . A delivery system ( 400 ) comprising:
an implantable heart valve ( 401 );
a valve delivery catheter ( 410 ) comprising a first lumen ( 415 ), wherein the valve delivery catheter ( 410 ) is reversibly coupled with the implantable heart valve ( 401 ) at a distal end ( 411 ) of the valve delivery catheter ( 410 ), and
an ultrasound imaging catheter ( 420 ) inserted through the center of the first lumen ( 415 ) of the valve delivery catheter ( 410 ), wherein the ultrasound imaging catheter ( 420 ) comprises a guide wire lumen ( 425 ) and an ultrasound imaging transducer ( 430 ) located at a distal end ( 421 ) of the ultrasound imaging catheter ( 420 ) and is configured to advance distally beyond the distal end ( 411 ) of the valve delivery catheter to a target site;
wherein the ultrasound imaging catheter ( 420 ) is configured to moveably pass:
(i) over a guide wire passing through the guide wire lumen ( 425 ) of the ultrasound imaging catheter ( 420 ),
(ii) through the first lumen ( 415 ) of the valve delivery catheter ( 410 ), and
(iii) through the implantable heart valve ( 401 ), and
wherein the ultrasound imaging transducer ( 430 ) can be moveably positioned to capture images of a surrounding anatomy, the valve delivery catheter ( 410 ) and the implantable heart valve ( 401 ) in real time during delivery of the implantable heart valve ( 401 ) in a subject,
wherein the ultrasound imaging transducer ( 430 ) remains stationary while the implantable heart valve ( 401 ) is pushed forward towards and exits through the distal end ( 411 ) of the delivery catheter ( 410 ) for deployment.
2 . The delivery system of claim 1 , wherein the implantable heart valve ( 401 ) comprises a self-expandable stent frame.
3 . The delivery system of claim 2 , wherein the implantable heart valve ( 401 ) is a prosthetic aortic valve and the delivery catheter ( 410 ) is adapted for transcatheter aortic valve replacement (TAVR) applications.
4 . The delivery system of claim 1 , wherein the position of the implantable heart valve ( 401 ) can be viewed circumferentially and in an axial direction.
5 . The delivery system of claim 1 , wherein the ultrasound imaging catheter ( 420 ) comprises radiopaque shaft markers that are coordinated with corresponding markers on the valve delivery catheter ( 410 ).
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 30, 2026
From: KHERADVAR, ARASH; SU, JIMMY L.
To: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Reel/Frame 074217/0217 →
Continuity (9)
Continuation In Part
PCTUS2012049645
· Aug 3, 2012
Provisional Application
61732117
· Nov 30, 2012
Provisional Application
61682663
· Aug 13, 2012
Provisional Application
61666657
· Jun 29, 2012
Provisional Application
61623410
· Apr 12, 2012
Provisional Application
61515679
· Aug 5, 2011
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