IP Library Granted Patent US 12,324,926
Granted Patent B2
US 12,324,926 · App. 17/830,411 · Granted Jun 10, 2025

Device and method for eradicating pathogens in nasal passages

Inventors: Christopher R. Brown (Greensburg, IN); Mark T. Volz (Batesville, IN)
Assignee: Neuraxis, Inc.
A61N5/0603A61N5/0624A61N2005/0607A61N2005/0626A61N2005/0632A61N2005/0652A61N2005/0663
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Quick Facts
Patent No.
US 12,324,926
App. No.
17/830,411
Granted
Jun 10, 2025
Kind
B2
Abstract

A device for eradicating at least one pathogen in a nasal passage of a human or animal may include a housing configured to be inserted into the nasal passage, at least one radiation source, configured to emit radiation, coupled to the housing such that at least a portion of a radiation emitting surface, upon insertion of the housing into the nasal passage, faces at least a portion of nasal lining of the nasal passage, and an electrical circuit carried by the housing and electrically connected to the at least one radiation source, the electrical circuit including at least one circuit component for controlling the at least one radiation source to emit the radiation to irradiate the nasal passage, the emitted radiation having a frequency or range of frequencies at which the at least one pathogen in the nasal passage, when irradiated by the emitted radiation, is eradicated.

Claims (43)

1. A device for eradicating at least one pathogen in a nasal passage of a human or animal, the device comprising:

a housing configured to be inserted into the nasal passage,

at least one radiation source, configured to emit radiation, coupled to the housing such that at least a portion of a radiation emitting surface of the at least one radiation source, upon insertion of the housing into the nasal passage, faces at least a portion of nasal lining of the nasal passage, and

an electrical circuit carried by the housing and electrically connected to the at least one radiation source, the electrical circuit including at least one circuit component for controlling the at least one radiation source to emit the radiation to irradiate the nasal passage, the emitted radiation having a frequency or range of frequencies at which the at least one pathogen in the nasal passage, when irradiated by the emitted radiation, is eradicated.

2. The device of claim 1 , wherein the at least one radiation source is configured to emit radiation at a frequency in a range of visible red light or to produce radiation in a range of visible red light frequencies.

3. The device of claim 1 , wherein the at least one radiation source is configured to emit visible red light at a wavelength in a range of approximately 630 nm-900 nm.

4. The device of claim 1 , wherein the at least one radiation source comprises at least one light emitting diode (LED).

5. The device of claim 1 , further comprising a source of electrical power carried by the housing, wherein the source of electrical power comprises at least one rechargeable or non-rechargeable battery.

6. The device of claim 1 , wherein the at least one pathogen is at least one of on the nasal lining, on nasal hair or cilia extending from the nasal lining or trapped in mucous within the nasal passage,

and wherein the emitted radiation has a frequency or range of frequencies configured to eradicate the at least one pathogen on the nasal lining, on the nasal hair or cilia extending from the nasal lining or trapped in the mucous within the nasal passage.

7. The device of claim 1 , wherein the housing is elongated in an axial direction and has a curved outer periphery in a radial direction,

and wherein the housing is configured to be moved axially along, and rotated within, the nasal passage to direct the emitted radiation to other portions of the nasal lining.

8. The device of claim 7 , wherein the at least one radiation source includes a plurality of radiation sources spaced apart axially along, and radially about, the housing.

9. The device of claim 1 , wherein the at least one pathogen includes COVID-19 virus.

10. A nasal passage irradiation system, comprising:

the device of claim 1 , wherein the electrical circuit includes wireless communication circuitry, and

a mobile communication device including wireless communication circuitry configured to communicate wirelessly with the wireless communication circuitry of the device, the mobile communication device further comprising a processor programmed to control operation of the device by wirelessly communicating operating instructions thereto.

11. A nasal passage irradiation system, comprising:

the device of claim 1 , and

a mobile communication device hard-wire connectable to the device and including a processor programmed to control operation of the device by communicating, via a hard-wire connection between the device and the mobile communication device, operating instructions to the electrical circuit of the device.

12. A device for eradicating at least one pathogen in a nasal passage of a human or animal, the device comprising:

a housing, elongated in an axial direction and having a curved outer periphery in a radial direction, configured to be inserted into the nasal passage,

at least one radiation source carried by the housing such that at least a portion of a radiation emitting surface of the at least one radiation source faces, with the housing inserted into the nasal passage, at least a portion of a nasal lining of the nasal passage, the at least one radiation source configured to emit radiation at a frequency or in a range of frequencies at which the at least one pathogen in the nasal passage, when irradiated by the emitted radiation, is eradicated, and

an electrical circuit carried by the housing and electrically connected to the at least one radiation source, the electrical circuit configured to control the at least one radiation source to emit the radiation to irradiate the nasal passage,

wherein the housing is configured to be moved axially along, and rotated within, the nasal passage to direct the emitted radiation along and about the nasal passage.

13. The device of claim 12 , wherein the at least one pathogen is at least one of on the nasal lining, on nasal hair or cilia extending from the nasal lining or trapped in mucous within the nasal passage,

and wherein the emitted radiation has a frequency or range of frequencies configured to eradicate the at least one pathogen on the nasal lining, on the nasal hair or cilia extending from the nasal lining or trapped in the mucous within the nasal passage.

14. The device of claim 12 , wherein the at least one radiation source includes a plurality of radiation sources spaced apart axially along, and radially about, the housing.

15. The device of claim 12 , wherein the at least one pathogen includes COVID-19 virus.

16. A nasal passage irradiation system, comprising:

the device of claim 12 , wherein the electrical circuit includes wireless communication circuitry, and

a mobile communication device including wireless communication circuitry configured to communicate wirelessly with the wireless communication circuitry of the device, the mobile communication device further comprising a processor programmed to control operation of the device by wirelessly communicating operating instructions thereto.

17. A nasal passage irradiation system, comprising:

the device of claim 12 , and

a mobile communication device hard-wire connectable to the device and including a processor programmed to control operation of the device by communicating, via a hard-wire connection between the device and the mobile communication device, operating instructions to the electrical circuit of the device.

18. A method for eradicating at least one pathogen in a nasal passage of a human or animal with a device having an elongated housing and at least one radiation source coupled to the elongated housing such that radiation emitted by the at least one radiation source is directed outwardly away from the housing, the radiation being at a frequency or in a range of frequencies at which the at least one pathogen in the nasal passage, when irradiated by the emitted radiation, is eradicated, the method comprising:

inserting the elongated housing axially into the nasal passage,

controlling, with electrical circuitry, the at least one radiation source to emit radiation toward a nasal lining of the nasal passage, and

moving the elongated housing axially along and rotatably within, the nasal passage to direct the emitted radiation axially along and about the nasal passage.

19. The method of claim 18 , wherein the electrical circuitry is carried by the elongated housing and the device includes a switch or button operatively coupled to the elongated housing,

and wherein controlling the at least one radiation source includes manually actuating the switch or button to cause the electrical circuitry to control the at least one radiation source to emit the radiation.

20. The method of claim 18 , wherein at least some of the electrical circuitry is carried by a mobile communication device wirelessly or hard-wire connected to the device,

and wherein controlling the at least one radiation source comprises controlling by the mobile communication device, via a corresponding wireless or hard-wire connection to the device, the at least one radiation source to emit the radiation.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 22, 2026
From: NEURAXIS, INC.
To: BROWN, CHRISTOPHER R.
Reel/Frame 073543/0654 →
CHANGE OF NAME Recorded Jun 10, 2022
From: INNOVATIVE HEALTH SOLUTIONS, INC.
To: NEURAXIS, INC.
Reel/Frame 060335/0195 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 7, 2022
From: BROWN, CHRISTOPHER R.; VOLZ, MARK T.
To: NEURAXIS, INC.
Reel/Frame 060117/0607 →
Continuity (2)
Provisional Application 63197609 · Jun 7, 2021
Related Publication 20220387817A1 · Dec 8, 2022
References Cited (97)
US 4305402A · Katims · 1981 [cited by applicant]
US 4646744A · Capel · 1987 [cited by applicant]
US 4865048A · Eckerson · 1989 [cited by applicant]
US 5084007A · Malin · 1992 [cited by applicant]
US 5094242A · Gleason · 1992 [cited by applicant]
US 5458625A · Kendall · 1995 [cited by applicant]
US 6296652B1 · Qingmin · 2001 [cited by applicant]
US 6212433B1 · Behl · 2001 [cited by applicant]
US 7092849B2 · Lafitte · 2006 [cited by applicant]
US 7103417B1 · Segel · 2006 [cited by applicant]
US 8308784B2 · Streeter · 2012 [cited by applicant]
US 8428719B2 · Napadow · 2013 [cited by applicant]
US 8465531B2 · Aunio · 2013 [cited by applicant]
US 8535361B2 · Lim · 2013 [cited by applicant]
US 8761872B2 · Hinrichsen · 2014 [cited by applicant]
US 8942814B2 · Szeles · 2015 [cited by applicant]
US 9662269B2 · Brown · 2017 [cited by applicant]
US 9782584B2 · Cartledge · 2017 [cited by applicant]
US 9839577B2 · Brown · 2017 [cited by applicant]
US 9901734B2 · Bennett · 2018 [cited by applicant]
US 10010479B2 · Brown · 2018 [cited by applicant]
US 10052257B2 · Nageshwar · 2018 [cited by applicant]
US 10058478B2 · Schnetz · 2018 [cited by applicant]
US 10086199B2 · Robertson · 2018 [cited by applicant]
US 10130275B2 · Nageshwar · 2018 [cited by applicant]
US 10130809B2 · Cartledge · 2018 [cited by applicant]
US 10413719B2 · Brown · 2019 [cited by applicant]
US 10471276B2 · Beckner · 2019 [cited by applicant]
US 10695568B1 · Covalin · 2020 [cited by applicant]
US 10806928B2 · Sharma · 2020 [cited by applicant]
US 20030050470A1 · An · 2003 [cited by applicant]
US 20030149451A1 · Chomenky · 2003 [cited by applicant]
US 20040044390A1 · Szeles · 2004 [cited by applicant]
US 20060122675A1 · Libbus · 2006 [cited by applicant]
US 20070198063A1 · Hunter · 2007 [cited by applicant]
US 20080051852A1 · Dietrich · 2008 [cited by applicant]
US 20080071132A1 · Lamoureux · 2008 [cited by examiner]
US 20080249439A1 · Tracey · 2008 [cited by applicant]
US 20100004715A1 · Fahey · 2010 [cited by applicant]
US 20100113965A1 · Kanevsky · 2010 [cited by applicant]
US 20100168822A1 · Szeles · 2010 [cited by applicant]
US 20100262205A1 · De Ridder · 2010 [cited by applicant]
US 20110160811A1 · Walker · 2011 [cited by applicant]
US 20110190569A1 · Simon · 2011 [cited by applicant]
US 20120226333A1 · Szeles · 2012 [cited by applicant]
US 20120253427A1 · Aunio · 2012 [cited by applicant]
US 20130150923A1 · Schnetz · 2013 [cited by applicant]
US 20140081368A1 · Szeles · 2014 [cited by applicant]
US 20140370476A1 · Nageshwar · 2014 [cited by applicant]
US 20140371608A1 · Nageshwar · 2014 [cited by applicant]
US 20140371621A1 · Nageshwar · 2014 [cited by applicant]
US 20150112405A1 · Brown · 2015 [cited by applicant]
US 20150112411A1 · Beckman · 2015 [cited by applicant]
US 20150265830A1 · Simon · 2015 [cited by applicant]
US 20160074663A1 · De Ridder · 2016 [cited by applicant]
US 20160113526A1 · Nageshwar · 2016 [cited by applicant]
US 20160144175A1 · Simon · 2016 [cited by applicant]
US 20170143247A1 · Nageshwar · 2017 [cited by applicant]
US 20170197081A1 · Charlesworth · 2017 [cited by applicant]
US 20180064603A1 · Brown · 2018 [cited by applicant]
US 20180256917A9 · Lim · 2018 [cited by examiner]
US 20180264282A1 · Bornstein · 2018 [cited by examiner]
US 20180280721A1 · Beckner · 2018 [cited by applicant]
US 20180296435A1 · Brown · 2018 [cited by applicant]
US 20190262229A1 · Brown · 2019 [cited by applicant]
US 20200121943A1 · Anderson · 2020 [cited by examiner]
US 20210128938A1 · Stasko · 2021 [cited by examiner]
AT 395106 · 1992 [cited by applicant]
EP 1335774 · 2003 [cited by applicant]
EP 2474339 · 2012 [cited by applicant]
WO 2005001706 · 2005 [cited by applicant]
WO 2011030210 · 2011 [cited by applicant]
WO 2014200488 · 2014 [cited by applicant]
WO 2014200489 · 2014 [cited by applicant]
WO 2014200492 · 2014 [cited by applicant]
WO 2014200498 · 2014 [cited by applicant]
WO 2014207512 · 2014 [cited by applicant]
WO 2015008154 · 2015 [cited by applicant]
WO 2016151377 · 2016 [cited by applicant]
WO 2019053625 · 2019 [cited by applicant]
International Search Report prepared for PCT/US2019/029172 mailed Jan. 28, 2020. [cited by applicant]
Extended Eurpean Search Report in Application No. 19850021.7-122 dated Dec. 8, 2021. [cited by applicant]
International Search Report prepared for PCT/US2020/039040 mailed Sep. 11, 2020. [cited by applicant]
Garcia-Argibay, M. et al., “Efficacy of binaural auditory beats in congnition, anxiety, and pain perception: a meta-analysis,” Psychological Research, Aug. 2, 2018, vol. 83, pp. 357-372. [cited by applicant]
Palaniappan, R. et al., “On the binaural brain entrainment indicating lower heart rate variability,” Cardiology, 2015, vol. 190, pp. 262-263. [cited by applicant]
Byung-Hyun, K. et al., “The Effect of White Noise and Pink Noise on the Brain Activity,” The Journal of the Korea Contents Association, 2017, 17(5) pp. 491-498. (English machine-translation appended). [cited by applicant]
Da Silva, V.F. et al., “Stimulation by Light and Sound: Therapeutic Effects in Humans. Systematic Review,” Clin Pract Epidemiol Ment Health, 2015, vol. 11, p. 150-4. [cited by applicant]
Gkolias, V. et al., “Reduced pain and analgesic use after acoustic binaural beats therapy in chronic pain—A double-blind randomized control cross-over trial,” European J. Pain, 2020, 24(9) pp. 1716-1729. [cited by applicant]
Perez, H.D.O. et al., “Binaural Beats through the Auitory Pathway: From Brainstem to Connectivity Patterns,” eNeuro, 2020, 7(2) 29 pages. [cited by applicant]
Mcconnel, P.A. et al., “Auditory driving of the autonomic nervous system: Listening to theta-frequency binaural beats post-exercise increases parasympathetic activation and sympathetic withdrawal,” Frontiers in Psycholo… [cited by applicant]
Graham, M.T. et al., “Simulations and human cadaver head studies to identify optimal acoustic receiver locations for minimally invasive photoacoustic-guided neurosurgery,” Photoacoustics, 2020, 14 pages. [cited by applicant]
Grose, J.H. et al., “Binaural beat salience,” Hear Res, 2013, 285(1-2) pp. 40-45. [cited by applicant]
Chaieb, L. et al., “Auditory beat stimulation and its effects on cognition and mood states,” Frontiers in Psychiatry, 2015, vol. 6, pp. 1-9. [cited by applicant]
Ablen, V. et al., “Brainwave entrainment for better sleep and post-sleep state of young elite soccer players—study,” European Journal of Sport Science, 2014, 14(5) pp. 393-402. [cited by applicant]
Wei, Q. et al., “Novel design of smart sleep-lighting system for improving the sleep environment of children,” Technology and Health Care, 2019, vol. 27, pp. S3-S13. [cited by applicant]
Seshagiri, C.V. et al., “Response Properties of Neighboring Neurons in the Auditory Midbrain for Pure-Tone Stimulation: A Tetrode Study,” J. Neurophysiol., 2007, vol. 98, pp. 2058-2073. [cited by applicant]
Padmanabhan, R. et al., “A prospective, randomised, controlled study examining binaural beat audio and pre-operative anxiety in patients undergoing general anaesthesia for day case surgery,” Anasthesia, 2005, 60(9) pp. … [cited by applicant]