IP Library Granted Patent US 11,604,243
Granted Patent B2
US 11,604,243 · App. 17/837,579 · Granted Mar 14, 2023

Systems and methods for estimating magnetic susceptibility through continuous motion in an MRI scanner

Inventors: Joseph Dagher (McLean, VA); Ben Berman (McLean, VA)
Assignee: The MITRE Corporation
G01R33/56509A61B5/055G01R33/34092G01R33/5608
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Quick Facts
Patent No.
US 11,604,243
App. No.
17/837,579
Granted
Mar 14, 2023
Kind
B2
Abstract

Systems and methods for estimating magnetic susceptibility of a patient through continuous motion in an MRI scanner are provided herein. In one or more examples, during the collection of data, the patient can be instructed to move their head or other part of the body in a continuous manner and for a fixed duration of time. During the fixed duration of time, magnitude a data from the RF signal can be received by one or more RF coils can be collected. The received and undersampled magnitude data can be converted to phase data which can then be converted to magnetic susceptibility. Thus magnetic susceptibility can be determined while allowing for continuous motion during the MRI scan, which can be more comfortable and feasible for the patient in contrast to techniques that require the patient to hold their body at a particular orientation in the scanner for a fixed duration of time.

Claims (57)

1. A system for determining magnetic susceptibility from magnetic resonance imaging (MRI) data of a portion of a patient's body undergoing an MRI scan, the system comprising:

a memory;

one or more processors; and

wherein the memory stores one or more programs that when executed by the one or more processors, cause the one or more processors to:

receive a plurality of MRI measurements, wherein the plurality of MRI measurements are obtained while the patient is continuously moving;

receive data corresponding to a plurality of user positions, wherein the data is obtained while the patient is continuously moving;

associate each of the MRI measurements of the received plurality of MRI measurements with a user position of the received data corresponding to the plurality of user positions;

categorize each associated MRI measurement and user position into a bin of a plurality of bins, wherein each bin of the plurality of bins is defined by a range of values corresponding to a position of the patient;

generate a phase image using one or more associated MRI measurements and user positions categorized in a first bin and one or more associated MRI measurements and user positions categorized in one or more bins adjacent to the first bin; and

determine magnetic susceptibility of the portion of the patient's body using the generated phase image.

2. The system of claim 1 , wherein the plurality of MRI measurements obtained while the patient is continuously moving is received from one or more radio frequency (RF) coils.

3. The system of claim 1 , wherein the data corresponding to a plurality of user positions obtained while the patient is continuously moving is received from a motion tracker.

4. The system of claim 3 , wherein the motion tracker includes a camera configured to capture the plurality of user positions that corresponds to the portion of the patient's body.

5. The system of claim 3 , wherein the motion tracker determines the plurality of user positions in two or more spatial dimensions.

6. The system of claim 1 , wherein a total range of motion of the patient is obtained while the patient is continuously moving and wherein the total range of motion is divided into a pre-determined number of ranges of values to form the plurality of bins.

7. The system of claim 6 , wherein each bin of the plurality of bins represents a range of values corresponding to the position of the patient's body in two or more spatial dimensions.

8. The system of claim 1 , wherein the range of values corresponding to the one or more bins adjacent to the first bin is proximal to the range of values corresponding to the first bin.

9. The system of claim 1 , wherein determining the magnetic susceptibility of the portion of the patient's body comprises:

calculating a magnetic field of each bin of the plurality of bins; and

calculating the magnetic susceptibility of the portion of the patient's body undergoing the MRI scan.

10. The system of claim 1 , wherein the one or more processors are caused to generate an image of the portion of the patient's body based on the determined magnetic susceptibility of the portion of the patient's body.

11. A method for determining magnetic susceptibility from magnetic resonance imaging (MRI) data of a portion of a patient's body undergoing an MRI scan, the method comprising:

receiving a plurality of MRI measurements, wherein the plurality of MRI measurements are obtained while the patient is continuously moving;

receiving data corresponding to a plurality of user positions, wherein the data is obtained while the patient is continuously moving;

associating each of the MRI measurements of the received plurality of MRI measurements with a user position of the received data corresponding to the plurality of user positions;

categorizing each associated MRI measurement and user position into a bin of a plurality of bins, wherein each bin of the plurality of bins is defined by a range of values corresponding to a position of the patient;

generating a phase image using one or more associated MRI measurements and user positions categorized in a first bin and one or more associated MRI measurements and user positions categorized in one or more bins adjacent to the first bin; and

determining magnetic susceptibility of the portion of the patient's body using the generated phase image.

12. The method of claim 11 , wherein the plurality of MRI measurements obtained while the patient is continuously moving is received from one or more radio frequency (RF) coils.

13. The method of claim 11 , wherein the data corresponding to a plurality of user positions obtained while the patient is continuously moving is received from a motion tracker.

14. The method of claim 13 , wherein the motion tracker includes a camera configured to capture the plurality of user positions that corresponds to the portion of the patient's body.

15. The method of claim 13 , wherein the motion tracker determines the plurality of user positions in two or more spatial dimensions.

16. The method of claim 11 , wherein a total range of motion of the patient is obtained while the patient is continuously moving and wherein the total range of motion is divided into a pre-determined number of ranges of values to form the plurality of bins.

17. The method of claim 16 , wherein each bin of the plurality of bins represents a range of values corresponding to the position of the patient's body in two or more spatial dimensions.

18. The method of claim 11 , wherein the range of values corresponding to the one or more bins adjacent to the first bin is proximal to the range of values corresponding to the first bin.

19. The method of claim 11 , wherein determining the magnetic susceptibility of the portion of the patient's body comprises:

calculating a magnetic field of each bin of the plurality of bins; and

calculating the magnetic susceptibility of the portion of the patient's body undergoing the MRI scan.

20. The method of claim 11 , wherein the one or more processors are caused to generate an image of the portion of the patient's body based on the determined magnetic susceptibility of the portion of the patient's body.

21. A non-transitory computer-readable storage medium comprising one or more programs for determining magnetic susceptibility from magnetic resonance imaging (MRI) data of a portion of a patient's body undergoing an MRI scan, wherein the one or more programs, when executed by one or more processors, cause the one or more processors to:

receive a plurality of MRI measurements, wherein the plurality of MRI measurements are obtained while the patient is continuously moving;

receive data corresponding to a plurality of user positions, wherein the data is obtained while the patient is continuously moving;

associate each of the MRI measurements of the received plurality of MRI measurements with a user position of the received data corresponding to the plurality of user positions;

categorize each associated MRI measurement and user position into a bin of a plurality of bins, wherein each bin of the plurality of bins is defined by a range of values corresponding to a position of the patient;

generate a phase image using one or more associated MRI measurements and user positions categorized in a first bin and one or more associated MRI measurements and user positions categorized in one or more bins adjacent to the first bin; and

determine magnetic susceptibility of the portion of the patient's body using the generated phase image.

22. The non-transitory computer-readable storage medium of claim 21 , wherein the plurality of MRI measurements obtained while the patient is continuously moving is received from one or more radio frequency (RF) coils.

23. The non-transitory computer-readable storage medium of claim 21 , wherein the data corresponding to a plurality of user positions obtained while the patient is continuously moving is received from a motion tracker.

24. The non-transitory computer-readable storage medium of claim 23 , wherein the motion tracker includes a camera configured to capture the plurality of user positions that corresponds to the portion of the patient's body.

25. The non-transitory computer-readable storage medium of claim 23 , wherein the motion tracker determines the plurality of user positions in two or more spatial dimensions.

26. The non-transitory computer-readable storage medium of claim 21 , wherein a total range of motion of the patient is obtained while the patient is continuously moving and wherein the total range of motion is divided into a pre-determined number of ranges of values to form the plurality of bins.

27. The non-transitory computer-readable storage medium of claim 26 , wherein each bin of the plurality of bins represents a range of values corresponding to the position of the patient's body in two or more spatial dimensions.

28. The non-transitory computer-readable storage medium of claim 21 , wherein the range of values corresponding to the one or more bins adjacent to the first bin is proximal to the range of values corresponding to the first bin.

29. The non-transitory computer-readable storage medium of claim 21 , wherein determining the magnetic susceptibility of the portion of the patient's body comprises:

calculating a magnetic field of each bin of the plurality of bins; and

calculating the magnetic susceptibility of the portion of the patient's body undergoing the MRI scan.

30. The non-transitory computer-readable storage medium of claim 21 , wherein the one or more processors are caused to generate an image of the portion of the patient's body based on the determined magnetic susceptibility of the portion of the patient's body.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 10, 2022
From: DAGHER, JOSEPH; BERMAN, BEN
To: THE MITRE CORPORATION
Reel/Frame 061722/0726 →
Continuity (2)
Continuation 17084237 · Oct 29, 2020
Related Publication 20220317221A1 · Oct 6, 2022