IP Library Granted Patent US 12,281,208
Granted Patent B2
US 12,281,208 · App. 17/844,026 · Granted Apr 22, 2025

Bioactive plastics with programmable degradation and microplastic elimination

Inventors: Ting Xu (Berkeley, CA); Christopher DelRe (Berkeley, CA); Junpyo Kwon (Berkeley, CA)
Assignee: The Regents of the University of California
C08J11/105C08L67/04C12P17/08C08J2367/04
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,281,208
App. No.
17/844,026
Granted
Apr 22, 2025
Kind
B2
Abstract

Nanoscopic dispersion of trace enzymes and random heteropolymers in plastics provides to fully functional plastics with eco-friendly microplastic elimination and programmable degradation.

Claims (21)

1. A bioactive plastic composition comprising an organic polymer and a nanoscopic dispersion of complexes of random heteropolymers and an enzyme that hydrolyzes the polymer, such that hydrolysis of the polymer by the enzyme imparts depolymerization and microplastic elimination, wherein the complexes are uniformly distributed within the composition, the complexes range in size from 10 nm to 500 nm, wherein the size of the complexes is the hydrodynamic diameter of the complexes, the composition comprises 0.001 to 5 wt % enzyme content, and wherein the random heteropolymers comprise varying ratios of a plurality of monomers selected from methyl methacrylate (MMA), oligo (ethylene glycol) methacrylate (OEGMA), 3-sulfopropyl methacrylate potassium salt (3-SPMA) and 2-ethylhexyl methacrylate (2-EHMA) wherein polymer/enzyme combinations are selected from selected from polycaprolactone/lipase, polylactic acid/proteinase K, and polyethylene terephthalate/PETase.

2. The composition of claim 1 , wherein the complexes range in size from 10 nm to 200 nm.

3. The composition of claim 1 , wherein the complexes range in size from 20 nm to 200 nm.

4. The composition of claim 1 , wherein the complexes range in size from 10 nm to 100 nm.

5. The composition of claim 1 , wherein the complexes range in size from 20 nm to 100 nm.

6. The composition of claim 1 , wherein the enzyme content is 0.001 to 1 wt %.

7. The composition of claim 1 , wherein the enzyme content is 0.01 to 1 wt %.

8. The composition of claim 1 , wherein the enzyme content is 0.001 to 0.1 wt %.

9. The composition of claim 1 , wherein the enzyme content is 0.01 to 0.1 wt %.

10. The composition of claim 1 , wherein the complexes range from 10 nm to 500 nm between crystalline polymer lamellae of the composition.

11. The composition of claim 1 , wherein the complexes range from 10 nm to 200 nm between crystalline polymer lamellae of the composition.

12. The composition of claim 1 , wherein the complexes range from 10 nm to 100 nm between crystalline polymer lamellae of the composition.

13. The composition of claim 1 , wherein the complexes range from 40 nm to 100 nm between crystalline polymer lamellae of the composition.

14. The composition of claim 1 , formulated in a conductive ink for 3-D printing.

15. The composition of claim 1 , formulated in a conductive ink for 3-D printing and comprising a precious metal filler, wherein the method provides 50 to 99% recovery of the precious metal filler.

16. The composition of claim 1 , configured to provide continuous degradation of the organic polymer and achieve 95% microplastic elimination.

17. The composition of claim 1 , configured to provide a polymer-based degradation mechanism with repolymerizable small molecule by-products via selective chain end scission rather than random chain scission.

18. The composition of claim 1 , configured to provide spatially- and temporally-programmable degradation of melt- or solution-processed host matrix due to the dependence of polymer degradation on local lamellae thickness regardless of bulk percent crystallinity.

19. A method of programmable degradation and microplastic elimination, the method comprising:

providing a bioactive plastic composition of claim 1 ; and

maintaining the composition under conditions wherein the enzyme cleaves the polymer backbone to achieve programmable degradation and microplastic elimination.

Assignments (2)
CONFIRMATORY LICENSE Recorded Sep 2, 2022
From: UNIVERSITY OF CALIFORNIA BERKELEY
To: UNITED STATES DEPARTMENT OF ENERGY
Reel/Frame 061375/0946 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 19, 2022
From: XU, TING; DELRE, CHRISTOPHER; KWON, JUNPYO
To: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Reel/Frame 060243/0971 →
Continuity (3)
Continuation PCTUS2021012108 · Jan 4, 2021
Provisional Application 62957307 · Jan 5, 2020
Related Publication 20220340731A1 · Oct 27, 2022
References Cited (7)
US 20090162337A1 · Gross · 2009 [cited by applicant]
US 20240026114A1 · Xu · 2024 [cited by examiner]
EP 1911472 · 2008 [cited by applicant]
WO 2019143578 · 2019 [cited by applicant]
Shohana Islam et al., Targeting microplastic particles in the void of diluted suspensions, Environment International, 123(2019) 428-435. [cited by applicant]
Written Opinion for priority PCT/US21/12108, filed Jan. 4, 2021) 9 pages (Apr. 16, 2021). [cited by applicant]
Extended European search report for related EP 21736205.2, 11 pages (May 31, 2023). [cited by applicant]