IP Library Granted Patent US 12,186,015
Granted Patent B2
US 12,186,015 · App. 17/863,615 · Granted Jan 7, 2025

Methods, devices, and systems for non-invasive delivery of microwave therapy

Inventors: Mark E. Deem (Mountain View, CA); Daniel E. Francis (Mountain View, CA); Jessi Ernest Johnson (Sunnyvale, CA); Steven W. Kim (Los Altos, CA); Alexey Salamini (San Francisco, CA)
Assignee: MiraDry, Inc.
A61B18/1815A61B18/18A61B34/10A61N5/02A61N5/025A61B2018/00005A61B2018/00017A61B2018/00023A61B2018/00029A61B2018/00041A61B2018/00452A61B2034/104A61B90/37A61N2005/007
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Quick Facts
Patent No.
US 12,186,015
App. No.
17/863,615
Granted
Jan 7, 2025
Kind
B2
Abstract

Methods, apparatuses and systems are provided for non-invasive delivery of microwave therapy. Microwave energy may be applied to epidermal, dermal and subdermal tissue of a patient to achieve various therapeutic and/or aesthetic results. In one embodiment, the microwave energy is applied to a target tissue via an energy delivery applicator connected to an energy generator. The energy delivery applicator may comprise one or more antennas, including monopole, dipole, slot and/or waveguide antennas (among others) that are used to direct the microwave energy to the target tissue. The energy delivery applicator may also comprise a cooling element for avoiding thermal destruction to non-target tissue and/or a suction device to localize thermal treatment at specific portions of a skin fold.

Claims (43)

1. A system for treating a skin tissue of a patient comprising:

a microwave energy generator;

an array of microwave antennas configured for placement proximate to the skin tissue, wherein the array of microwave antennas includes one or more waveguide antennas with a cross-sectional size configured to a desired operational frequency and with a field configuration of a waveguide depending on a desired clinical objective and a geometry of a particular anatomical area to be treated;

a cooling plate configured for placement in contact with the skin tissue and protectively cool a layer of skin above a target layer;

a cooling fluid circuit configured for placement adjacent to the cooling plate, wherein the cooling plate further comprises a flow chamber configured to retain a liquid coolant between the cooling plate and the array of microwave antennas; and

a suction element configured for elevating the skin tissue and placing the skin tissue in contact with the cooling plate,

wherein the array of microwave antennas is configured to deliver microwave energy to the skin tissue sufficient to create a thermal effect in a target tissue within the skin tissue, and

wherein a distal end of the waveguide of the one or more waveguide antennas is operably connected to the cooling fluid circuit at least partially superimposed on the cooling plate.

2. The system of claim 1 , wherein the cooling plate comprises a thermally-conductive cooling plate.

3. The system of claim 2 , wherein the thermally-conductive cooling plate is substantially transparent to the microwave energy.

4. The system of claim 1 , wherein the cooling plate is configured to cool the skin tissue and physically separate the skin tissue from the array of microwave antennas.

5. The system of claim 1 , wherein the thermally-conductive cooling plate comprises a ceramic plate.

6. The system of claim 1 , wherein the liquid coolant is selected from the group consisting of water, distilled water, deionized water, alcohol, and oil.

7. The system of claim 1 , wherein the suction element comprises a suction chamber configured for elevating target tissue comprising a portion of the skin tissue from underlying tissue.

8. The system of claim 1 , further comprising a temperature sensor comprising a thermocouple configured for monitoring the temperature of the skin tissue.

9. The system of claim 1 , wherein the microwave energy generator delivers the microwave energy at a frequency of between about 2.4 GHz to 9.2 GHz.

10. The system of claim 1 , wherein the one or more waveguide antennas being configured for simultaneous or sequential treatment of multiple sections of the skin tissue and to radiate electromagnetic radiation in the lowest-order Transverse Electric modes.

11. A method for treating a skin tissue of a patient comprising:

providing a microwave energy generator;

placing an array of waveguide antennas proximate to the skin tissue, wherein the array of microwave antennas includes one or more waveguide antennas with a cross-sectional size configured to a desired operational frequency and with a field configuration of a waveguide depending on a desired clinical objective and a geometry of a particular anatomical area to be treated;

placing a cooling plate in contact with the skin tissue and protectively cooling a layer of skin above a target layer;

placing a cooling fluid circuit adjacent to the cooling plate, wherein the cooling plate further comprises a flow chamber to retain a liquid coolant between the cooling plate and the array of microwave antennas;

using a suction element to elevate the skin tissue and placing the skin tissue in contact with the cooling plate; and

delivering energy to the skin tissue via the array of microwave antennas sufficient to create a thermal effect in a target tissue within the skin tissue,

wherein the array of microwave antennas is configured to deliver microwave energy to the skin tissue sufficient to create a thermal effect in a target tissue within the skin tissue, and

wherein a distal end of the waveguide of the one or more waveguide antennas is operably connected to the cooling fluid circuit at least partially superimposed on the cooling plate.

12. The method of claim 11 , wherein the microwave energy generator delivers the microwave energy at a frequency of between about 2.4 GHz to 9.2 GHz.

13. The method of claim 11 , wherein the cooling plate cools the skin tissue and physically separates the skin tissue from the array of microwave antennas.

14. The method of claim 11 , wherein the suction element comprises a suction chamber, the method further comprising using the suction chamber to elevate target tissue comprising a portion of the skin tissue from underlying tissue.

15. The method of claim 11 , further comprising providing a temperature sensor having a thermocouple, wherein the thermocouple monitors the temperature of the skin tissue.

16. The method of claim 11 , wherein the cooling plate comprises a thermally-conductive cooling plate substantially transparent to the microwave energy.

17. The method of claim 16 , wherein the thermally-conductive cooling plate comprises a ceramic plate.

18. The method of claim 11 , wherein the liquid coolant is selected from the group consisting of water, distilled water, deionized water, alcohol, and oil.

19. The method of claim 11 , wherein the one or more waveguide antennas being configured for simultaneous or sequential treatment of multiple sections of the skin tissue and to radiate electromagnetic radiation in the lowest-order Transverse Electric modes.

20. A system for treating a skin tissue of a patient comprising:

a microwave energy generator configured to deliver microwave energy at a frequency of between about 2.4 GHz to 9.2 GHz;

an array of microwave antennas configured for placement proximate to the skin tissue, wherein the array of microwave antennas includes one or more waveguide antennas with a cross-sectional size configured to a desired operational frequency and with a field configuration of a waveguide depending on a desired clinical objective and a geometry of a particular anatomical area to be treated;

a cooling plate configured for placement in contact with the skin tissue and protectively cool a layer of skin above a target layer, wherein the cooling plate comprises a thermally-conductive cooling plate substantially transparent to the microwave energy;

a cooling fluid circuit configured for placement adjacent to the cooling plate, wherein the cooling plate further comprises a flow chamber configured to retain a liquid coolant between the cooling plate and the array of microwave antennas; and

a suction element configured for elevating the skin tissue and placing the skin tissue in contact with the cooling plate, wherein the suction element is operatively coupled to a vacuum source,

wherein the array of microwave antennas is configured to deliver the microwave energy to the skin tissue sufficient to create a thermal effect in a target tissue within the skin tissue,

wherein a distal end of the waveguide of the one or more waveguide antennas is operably connected to the cooling fluid circuit at least partially superimposed on the cooling plate, and

wherein the one or more waveguide antennas being configured for simultaneous or sequential treatment of multiple sections of the skin tissue and to radiate electromagnetic radiation in the lowest-order Transverse Electric modes.

Assignments (5)
SECURITY INTEREST Recorded Oct 1, 2024
From: MIRADRY, INC.
To: WESTERN ALLIANCE BANK
Reel/Frame 068752/0533 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 12, 2022
From: DEEM, MARK E.; GIFFORD, HANSON; KIM, STEVEN; SALAMINI, ALEXEY
To: THE FOUNDRY, INC.
Reel/Frame 061059/0362 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 12, 2022
From: THE FOUNDRY, INC.
To: MIRAMAR LABS, INC.
Reel/Frame 061059/0434 →
CHANGE OF NAME Recorded Sep 12, 2022
From: MIRAMAR LABS, INC.
To: MIRAMAR TECHNOLOGIES, INC.
Reel/Frame 061409/0070 →
CHANGE OF NAME Recorded Sep 12, 2022
From: MIRAMAR TECHNOLOGIES, INC.
To: MIRADRY, INC.
Reel/Frame 061409/0073 →
Continuity (7)
Continuation 16673665 · Nov 4, 2019
Continuation 15288949 · Oct 7, 2016
Continuation 12450860
Provisional Application 61045937 · Apr 17, 2008
Provisional Application 61013274 · Dec 12, 2007
Provisional Application 60912899 · Apr 19, 2007
Related Publication 20230019979A1 · Jan 19, 2023
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