IP Library Granted Patent US 12,090,131
Granted Patent B2
US 12,090,131 · App. 17/903,372 · Granted Sep 17, 2024

Therapeutic use of compounds

Inventors: Robin Simon Brooke Williams (Egham, GB); Matthew Walker (London, GB)
Assignee: UCL BUSINESS LTD
A61K31/20
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Quick Facts
Patent No.
US 12,090,131
App. No.
17/903,372
Granted
Sep 17, 2024
Kind
B2
Abstract

A compound having the formula (I) R1-COOH. R1 is an alkyl or alkenyl group having a C 7-11 backbone, optionally branched with a C 1-6 alkyl group at any C position in the backbone, or a pharmaceutically acceptable salt, amide or ester thereof. The backbone of the alkyl or alkenyl group, and/or the branched alkyl groups, are optionally interrupted by one or more heteroatoms, provided that when R1 is an alkyl group having a C 7 backbone, the branching does not consist only of a hexyl group at the a carbon of R1, or only of a methyl group at the γ carbon of R1, or of only single methyl groups at both the β and ω-1 carbons of R1, and provided that when R1 is an alkyl group having a C 8 or C 11 backbone, the branching does not consist only of a propyl group at the a carbon of R1.

Claims (1)

1. A method of treatment of chorea in a subject in need thereof, the method comprising administering an effective amount of decanoic acid and/or a pharmaceutically acceptable salt or ester thereof to the subject.

Assignments (2)
CHANGE OF NAME Recorded Aug 19, 2024
From: UCL BUSINESS PLC
To: UCL BUSINESS LTD
Reel/Frame 068688/0182 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 8, 2022
From: WILLIAMS, ROBIN SIMON BROOKE; WALKER, MATTHEW
To: UCL BUSINESS PLC
Reel/Frame 061022/0249 →
Priority Claims (1)
GB 1020133 · Nov 26, 2010 · national
Continuity (3)
Continuation 16722340 · Dec 20, 2019
Continuation 13989360
Related Publication 20230146709A1 · May 11, 2023