IP Library Granted Patent US 12,509,373
Granted Patent B2
US 12,509,373 · App. 17/921,999 · Granted Dec 30, 2025

Composition and method for the removal of biofilm

Inventors: Rishi Trivedi (Wilmington, DE); Bei Yin (Wilmington, DE)
C02F1/50A01N35/02A01N43/16A01P1/00A01N2300/00C02F2103/365C02F2303/04
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Quick Facts
Patent No.
US 12,509,373
App. No.
17/921,999
Granted
Dec 30, 2025
Kind
B2
Abstract

The present invention relates to a synergistic composition and method for removing biofilm using glutaraldehyde and analogs of mannose.

Claims (16)

1 . A synergistic composition useful for the removal of biofilm comprising:

i) glutaraldehyde; and

ii) 2-deoxy-D-glucose.

2 . The synergistic composition of claim 1 wherein the weight ratio of glutaraldehyde to 2-deoxy-D-glucose is 2.5:1 to 1:60.

3 . A method to remove biofilm comprising:

i. providing an aqueous system that comprises a biofilm with at least one sulfate-reducing prokaryote; and

ii. contacting the biofilm with the synergistic composition of claim 1 .

4 . The method of claim 3 wherein the sulfate-reducing prokaryote comprises Desulfovibrio vulgaris.

5 . A synergistic composition useful for the removal of biofilm comprising:

i) glutaraldehyde; and

ii) α-methyl-mannoside.

6 . The synergistic composition of claim 5 wherein the weight ratio of glutaraldehyde to α-methyl-mannoside is 2.5:1 to 1:60.

7 . A method to remove biofilm comprising:

i. providing an aqueous system that comprises at least one sulfate-reducing prokaryote; and

ii. contacting the aqueous system with the synergistic composition of claim 5 .

8 . The method of claim 7 wherein the sulfate-reducing prokaryote comprises Desulfovibrio vulgaris.

Assignments (6)
NUNC PRO TUNC ASSIGNMENT Recorded Oct 13, 2025
From: YIN, BEI; TRIVEDI, RISHI
To: DDP SPECIALTY ELECTRONIC MATERIALS US, LLC
Reel/Frame 072550/0031 →
CHANGE OF NAME Recorded Oct 13, 2025
From: DDP SPECIALTY ELECTRONIC MATERIALS US, INC.
To: DDP SPECIALTY ELECTRONIC MATERIALS US, LLC
Reel/Frame 073066/0875 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 13, 2025
From: MC (US) 3 LLC
To: LANXESS CORPORATION
Reel/Frame 073067/0076 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 13, 2025
From: DDP SPECIALTY ELECTRONIC MATERIALS US, LLC
To: NUTRITION & BIOSCIENCES USA 1, LLC
Reel/Frame 073086/0156 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 17, 2025
From: NUTRITION & BIOSCIENCES USA 1, LLC
To: MC (US) 3 LLC
Reel/Frame 072903/0129 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 10, 2023
From: NUTRITION & BIOSCIENCES USA 1, LLC
To: MC (US) 3 LLC
Reel/Frame 062650/0041 →
Continuity (2)
Provisional Application 63017415 · Apr 29, 2020
Related Publication 20230183108A1 · Jun 15, 2023
References Cited (6)
US 7060486B2 · Wood et al. · 2006 [cited by applicant]
US 20100305132A1 · Yin · 2010 [cited by examiner]
US 20170223955A1 · Yin · 2017 [cited by examiner]
US 20200138024A1 · Yin · 2020 [cited by examiner]
Kull, F.C.; Eisman, P.C.; Sylwestrowicz, H.D. and Mayer, R.L., in Applied Microbiology 9:538-541 (1961). [cited by applicant]
International Search Report from corresponding International Application No. PCT/US2021/028741 , dated Jul. 1, 2021, two pages. [cited by applicant]