Composition and method for the removal of biofilm
View Patent ↗The present invention relates to a synergistic composition and method for removing biofilm using glutaraldehyde and analogs of mannose.
1 . A synergistic composition useful for the removal of biofilm comprising:
i) glutaraldehyde; and
ii) 2-deoxy-D-glucose.
2 . The synergistic composition of claim 1 wherein the weight ratio of glutaraldehyde to 2-deoxy-D-glucose is 2.5:1 to 1:60.
3 . A method to remove biofilm comprising:
i. providing an aqueous system that comprises a biofilm with at least one sulfate-reducing prokaryote; and
ii. contacting the biofilm with the synergistic composition of claim 1 .
4 . The method of claim 3 wherein the sulfate-reducing prokaryote comprises Desulfovibrio vulgaris.
5 . A synergistic composition useful for the removal of biofilm comprising:
i) glutaraldehyde; and
ii) α-methyl-mannoside.
6 . The synergistic composition of claim 5 wherein the weight ratio of glutaraldehyde to α-methyl-mannoside is 2.5:1 to 1:60.
7 . A method to remove biofilm comprising:
i. providing an aqueous system that comprises at least one sulfate-reducing prokaryote; and
ii. contacting the aqueous system with the synergistic composition of claim 5 .
8 . The method of claim 7 wherein the sulfate-reducing prokaryote comprises Desulfovibrio vulgaris.