IP Library › Granted Patent US 12,036,117
Granted Patent B2
US 12,036,117 · App. 17/959,790 · Granted Jul 16, 2024

Prosthetic valve with natural blood flow

Inventors: Shmuel Banai (Tel Aviv, IL); Kathleen Hung (New Westminster, CA); Aaron J. Chalekian (Savage, MN); Karen Tsoek-Ji Wong (Richmond, CA); Eric Soun-Sang Fung (Vancouver, CA); Connor Lucas Haberl (Vancouver, CA); David Andrew Moffatt (Richmond, CA)
Assignee: Neovasc Tiara Inc.
A61F2/2418A61F2/2412A61F2002/068A61F2/2448A61F2/2454A61F2/2463A61F2/2466
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Quick Facts
Patent No.
US 12,036,117
App. No.
17/959,790
Granted
Jul 16, 2024
Kind
B2
Abstract

A prosthetic valve may be formed to direct flow out of the outflow orifice toward a posterior portion of a heart wall. The prosthetic valve includes an expandable frame which may be covered with a cover that is suturelessly attached to the frame. The prosthetic valve may also include an outflow orifice size which is controlled. Methods of using these devices are also disclosed.

Claims (45)

1. A prosthetic valve comprising:

a radially expandable frame comprising:

an annular region defining a longitudinal axis;

an atrial flange extending from a first end of the annular region;

a ventricular skirt extending from a second end of the annular region; and

at least one anchor tab;

a covering disposed along at least a portion of the annular region; and

at least one leaflet disposed within the radially expandable frame, the at least one leaflet being angled relative to the longitudinal axis;

wherein:

the at least one leaflet comprises an anterior leaflet configured to direct blood flow therethrough toward a posterior wall of a heart of a patient;

the at least one leaflet comprises a posterior leaflet that is shorter in length than the anterior leaflet;

one of the posterior leaflet and anterior leaflet is immobile; and another of the posterior leaflet and anterior leaflet is mobile.

2. The prosthetic valve of claim 1 , wherein the covering is disposed on the ventricular skirt.

3. The prosthetic valve of claim 1 , wherein the covering is disposed on an exterior of the radially expandable frame.

4. The prosthetic valve of claim 1 , wherein the at least one leaflet is made of a flexible material.

5. The prosthetic valve of claim 1 , wherein:

an inflow edge of the anterior leaflet is disposed more anteriorly than an outflow edge; and

the outflow edge of the anterior leaflet is disposed more posteriorly than the inflow edge.

6. The prosthetic valve of claim 1 , wherein the anterior leaflet is arcuate so as to form a concave portion facing radially inward relative to the longitudinal axis.

7. The prosthetic valve of claim 1 , wherein the annular region is D-shaped.

8. The prosthetic valve of claim 1 , wherein the posterior leaflet is smaller in width than the anterior leaflet.

9. The prosthetic valve of claim 1 , wherein:

an outflow edge of the posterior leaflet extends axially away from the radially expandable frame; and

an outflow edge of the anterior leaflet extends at an angle from an anterior side of the radially expandable frame to a posterior side of the radially expandable frame.

10. The prosthetic valve of claim 1 , wherein the at least one leaflet is coupled to a commissure post.

11. The prosthetic valve of claim 1 , wherein the at least one leaflet is angled so as to be configured to direct blood flow toward a posterior wall of a heart into which the prosthetic valve is to be implanted.

12. The prosthetic valve of claim 1 , wherein the at least one leaflet is offset toward a posterior side of device relative to the longitudinal axis.

13. A method for deploying a prosthetic valve in a heart of a patient, said method comprising:

providing a prosthetic valve having a radially expandable frame with an annular region defining a longitudinal axis, an atrial flange adjacent a first end of the annular region, a prosthetic valve mechanism having an outflow orifice adjacent a second end of the annular region opposite the first end, a ventricular skirt adjacent the second end, at least one anchor tab and a covering disposed along at least a portion of the annular region;

radially expanding the frame into engagement with a native valve in the heart of the patient; and

directing fluid flow through the prosthetic valve mechanism and out the outflow orifice toward a posterior portion of the patient's heart via one or more leaflets disposed within the radially expandable frame;

wherein:

the one or more leaflets comprises an anterior leaflet configured to direct blood flow therethrough toward a posterior wall of a heart of a patient;

the one or more leaflets comprises a posterior leaflet that is shorter in length than the anterior leaflet;

one of the posterior leaflet and anterior leaflet is immobile; and

another of the posterior leaflet and anterior leaflet is mobile.

14. The method of claim 13 , wherein directing fluid flow through the prosthetic valve mechanism and out the outflow orifice toward a posterior portion of the patient's heart via one or more leaflets disposed within the radially expandable frame comprises:

curving the fluid flow with the one or more leaflets.

15. The method of claim 13 , wherein directing fluid flow through the prosthetic valve mechanism and out the outflow orifice toward a posterior portion of the patients heart via one or more leaflets disposed within the radially expandable frame comprises:

moving at least one of the one or more leaflets.

16. The method of claim 13 , wherein directing fluid flow through the prosthetic valve mechanism and out the outflow orifice toward a posterior portion of the patient's heart via one or more leaflets disposed within the radially expandable frame comprises:

directing fluid flow between the anterior leaflet and the posterior leaflet.

17. The method of claim 16 , wherein:

the frame is D-shaped in cross-section when expanded; and

the anterior leaflet and posterior leaflet form a circular cross-sectional area.

Assignments (2)
MERGER Recorded Aug 6, 2026
From: NEOVASC TIARA INC.
To: NEOVASC INC.
Reel/Frame 076131/0630 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 4, 2022
From: BANAI, SHMUEL; HUNG, KATHLEEN; CHALEKIAN, AARON J.; WONG, KAREN TSOEK-JI; FUNG, ERIC SOUN-SANG; HABERL, CONNOR LUCAS; MOFFATT, DAVID ANDREW
To: NEOVASC TIARA INC.
Reel/Frame 061308/0758 →
Continuity (3)
Continuation 16845870 · Apr 10, 2020
Provisional Application 62831922 · Apr 10, 2019
Related Publication 20230100125A1 · Mar 30, 2023
Cited By (1)
US 12,193,932