System for targeted medical intervention using a magnetic field
View Patent ↗A system for steering magnetotactic entities in a subject having a propulsion system for navigating in a body of the subject using a magnetic field sufficient for influencing the direction of the magnetotactic entities while not without inducing a displacement force on the magnetotactic entities; it has a table for receiving a subject; three pairs of magnetic heads for generating the magnetic field for influencing a direction of the magnetotactic entities in a subject; and a support structure, surrounding the table, for supporting each of the magnetic heads of the three pairs of magnetic heads in a configuration wherein each pair is aligned along one of three axes and wherein each of the magnetic heads of each pair of the three pairs are facing one another, wherein the magnetic heads of the three pairs surround the table.
1 . The application has been amended as follows:
system for steering magnetotactic entities in a subject, the magnetotactic entities having a propulsion system for navigating in a body of the subject using a magnetic field sufficient for influencing the direction of the magnetotactic entities, comprising:
a table for receiving a subject;
three pairs of magnetic heads for generating the magnetic field for influencing a direction of the magnetotactic entities in a subject; and
a support structure, surrounding the table, for supporting each of the magnetic heads of the three pairs of magnetic heads in a configuration wherein each pair is aligned along one of three axes and wherein each of the magnetic heads of each pair of the three pairs are facing one another, wherein the magnetic heads of the three pairs surround the table,
wherein a first magnetic head of a first pair of the three pairs is placed under the table,
joined to a portion of the support structure, wherein the first magnetic head of the first pair of the three pairs is at an angle with an axis that is orthogonal with a length of the table, and
wherein the support structure comprises a support arch for receiving a first magnetic head of a second pair of the three pairs of magnetic heads, a first magnetic head of a third pair of the three pairs of magnetic heads and a second magnetic head of the first pair of the three pairs of magnetic heads.
2 . The system as defined in claim 1 , wherein legs of the support arch are oriented with respect to one another to create an angle of 90 degrees.
3 . The system as defined in claim 1 , wherein the first magnetic head of the second pair of the three pairs of magnetic heads is received at or near a bottom of a first leg portion of the support arch and the first magnetic head of the third pair of the three pairs of magnetic heads is received at or near a bottom of a second leg portion of the support arch.
4 . The system as defined in claim 1 , wherein the support structure comprises two support arms, wherein a first of the two support arms receives a second magnetic head of a second pair of the three pairs of magnetic heads and a second of the two support arms receives a second magnetic head of a third pair of the three pairs of magnetic heads.
5 . The system as defined in claim 4 , wherein the first of the two support arms receives the second magnetic head of a second pair of the three pairs of magnetic heads at or near a top of the first of the two support arms and the second of the two support arms receives a second magnetic head of a third pair of the three pairs of magnetic heads at a top of the second of the two support arms.
6 . The system as defined in claim 1 , wherein the support structure comprises:
a support arch for receiving a first magnetic head of a first pair of the three pairs of magnetic heads, a first magnetic head of a second pair of the three pairs of magnetic heads, and a first magnetic head of a third pair of the three pairs; and
two support arms, wherein a first of the two support arms receives a second magnetic head of the second pair of the three pairs of magnetic heads and a second of the two support arms receives a second magnetic head of the third pair of the three pairs of magnetic heads.
7 . The system as defined in claim 5 , wherein the two support arms are each positioned on opposite sides at or near a first end of the table and the support arch is positioned at or near a second end of the table opposite the first end of the table.
8 . The system as defined in claim 6 , further comprising an x-ray image intensifier located between the support arch and one of the two support arms for generating imaging information of the subject.
9 . The system as defined in claim 1 , further comprising an actuator for displacing the table along at least one of the three axes.
10 . The system as defined in claim 9 , wherein the actuator is configured to displace the table vertically.
11 . The system as defined in claim 8 , wherein the actuator is configured to rotate the table.
12 . The system as defined in claim 1 , wherein the three pairs of magnetic heads are configured to generate a 3D convergence point that is a point, unbounded in space, to which the magnetotactic entities following a direction of the magnetic field in an aggregation zone will move to and aggregate in the body of the subject.
13 . A system for steering self-propelled magnetotactic entities in a body of a subject, the system comprising:
a first vertical support oriented in a transverse direction (y-axis) and having an upper portion in communication with a first lower portion (+y) and a second lower portion (−y);
a second vertical support spaced from the first lower portion (+y) of the first vertical support in a longitudinal direction (+x);
a third vertical support spaced from the second lower portion (−y) of the first vertical support in the longitudinal direction (+x) and spaced from the second vertical support in the transverse direction (y-axis); and
a first pair of opposing magnetic heads arranged along a first axis, a first magnetic head of the first pair of opposing magnetic heads being affixed to the upper portion of the first vertical support and a second magnetic head of the first pair of opposing magnetic heads being affixed to a floor, the first axis forming an acute angle with respect to a plane of the floor;
a second pair of opposing magnetic heads arranged along a second axis substantially orthogonal to the first axis, a first magnetic head of the second pair of opposing magnetic heads being affixed to the second lower portion (−y) of the first vertical support and a second magnetic head of the second pair of opposing magnetic heads being affixed to an upper portion of the second vertical support (+y); and
a third pair of opposing magnetic heads arranged along a third axis substantially orthogonal to the first axis and the second axis, a first magnetic head of the third pair of opposing magnetic heads being affixed to the first lower portion (+y) of the first vertical support and a second magnetic head of the third pair of opposing magnetic heads being affixed to an upper portion of the third vertical support.