IP Library › Granted Patent US 12,589,215
Granted Patent B2
US 12,589,215 · App. 17/995,393 · Granted Mar 31, 2026

Mechanical respirator

Inventors: Kevin N. Wood (San Diego, CA); Tyler Lestak (San Diego, CA); Jack Lucas (San Diego, CA); Ener Arvizu-Munoz (San Diego, CA)
Assignee: San Diego State University (SDSU) Foundation
A61M16/125A61M16/0084A61M16/024A61M16/20A61M16/202A61M16/208A61M16/209A61M2016/0027A61M16/0063A61M16/0078A61M16/1065A61M16/204A61M16/205A61M2202/0208A61M2205/106
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Quick Facts
Patent No.
US 12,589,215
App. No.
17/995,393
Granted
Mar 31, 2026
Kind
B2
Abstract

In alternative embodiments, provided are mechanical ventilators and methods for making and using them.

Claims (41)

1 . A mechanical ventilator, comprising:

a fluid flow controller disposed to receive a mixed gas along at least a first line, the mixed gas including oxygen from an oxygen source and compressed air from a compressed air source/generator operably connected to the fluid flow controller, the fluid flow controller having a fluid flow controller output line operably connected to a patient line, the fluid flow controller being driven by an on-off valve to deliver the mixed gas to the patient line at appropriate intervals where a tidal volume (TV), inspiratory time, and/or peak inspiratory pressure (PIP) arise from fluid forced to a patient as dictated by the fluid flow controller;

a controller for the on-off valve;

a second line disposed to receive the mixed gas, the second line being configured to create a continuous, constantly flowing positive end-expiratory pressure (PEEP) for delivering the mixed gas along a PEEP output line to the patient line;

a junction combining the fluid flow controller output line and the PEEP output line, the patient line being operatively connected to and downstream of the junction; and

a uni-directional valve disposed within or upstream of the patient line and downstream of the fluid flow controller output line.

2 . The mechanical ventilator of claim 1 , wherein the fluid flow controller comprises a bag-valve-mask (BVM), the on/off valve, and a pneumatic actuator;

wherein the first line is operably connected to the BVM and is provided by a first compressed fluid output line for connecting to the compressed air source;

wherein a first oxygen output line for connecting to the oxygen source is operably connected to the BVM; and

wherein the on/off valve is disposed within the first compressed fluid output line.

3 . The mechanical ventilator of claim 1 , wherein the second line is operatively connected to a second compressed fluid output line and to a second oxygen output line;

wherein the mechanical ventilator further comprises a pressure control valve and a manometer disposed within each of the second compressed fluid output line and the second oxygen output line for controlling PEEP flow of the mixed gas along the PEEP output line.

4 . The mechanical ventilator of claim 1 , wherein the on/off valve is configured to control one or more of inspiration time or breath rate to the patient line; and

wherein the on/off valve is further configured to create a rhythmic flow of the mixed gas to the patient line.

5 . The mechanical ventilator of claim 1 , wherein the on/off valve is triggered by a pressure sensor disposed in the patient line.

6 . The mechanical ventilator of claim 1 , further comprising:

a pressure-release valve disposed within the patient line.

7 . The mechanical ventilator of claim 1 , wherein the controller is configured to control the ventilator to deliver a selected tidal volume (TV) at one or more inspiratory rates.

8 . The mechanical ventilator of claim 1 , wherein the controller is incorporated within a Printed Circuit Board Assembly (PCBA); and

wherein the fluid flow controller and the controller are contained within a housing.

9 . The mechanical ventilator of claim 8 ,

wherein the ventilator further comprises an expiratory line disposed downstream of the uni-directional valve and having an output leading to environment;

wherein the uni-directional valve comprises a three-way check valve that is operably connected to the fluid flow controller output line, the patient line, and the expiratory line; and

wherein the housing includes ports for operatively connecting to the compressed air source, the oxygen source, and the three-way valve.

10 . The mechanical ventilator of claim 1 , further comprising:

a pressure sensor disposed along one or more of the patient line, the first line, and the second line, the pressure sensor(s) being coupled to the controller; and

an audible and/or visible alarm coupled to the controller for indicating an alarm condition based on values from the pressure sensor(s).

11 . The mechanical ventilator of claim 1 , further comprising:

a display coupled to the controller for indicating a status of the mechanical ventilator.

12 . A method for operating a mechanical ventilator, the mechanical ventilator including a fluid flow controller disposed to receive a mixed gas along at least a first line, the mixed gas including oxygen from an oxygen source and compressed air from a compressed air source operably connected to the fluid flow controller, the fluid flow controller having a fluid flow controller output line operably connected to a patient line, the fluid flow controller being controlled by a pneumatic actuator powered by an on/off valve to deliver the mixed gas to the patient line at a tidal volume (TV), inspiratory time, and/or peak inspiratory pressure (PIP) provided by the fluid flow controller, a controller for controlling the on/off valve, a second line disposed to receive the mixed gas, the second line being configured to create a continuous positive end-expiratory pressure (PEEP) for delivering the mixed gas along a PEEP output line to the patient line, a junction combining the fluid flow controller output line and the PEEP output line, the patient line being operatively connected to and downstream of the junction, and a three-way valve disposed within or upstream of the patient line and downstream of the fluid flow controller output line, the method comprising:

receiving an inspiratory time, a patient pressure, and a respiratory rate;

providing a model that relates the inspiratory time, the patient pressure, a system pressure, and a patient flow pressure to a tidal volume;

determining one or more ventilator parameters to achieve delivery of desired breaths to a patient along the patient line using the model; and

controlling operation of the mechanical ventilator based on the determined ventilator parameters.

13 . The method of claim 12 , wherein the model is trained using a machine learning algorithm.

14 . The method of claim 12 , wherein controlling operation occurs according to one or more of a plurality of selectable modes;

wherein the selectable modes comprises one or more of:

Continuous Machine Ventilation (CMV);

Intermediate Machine Ventilation (IMV);

Spontaneous Continuous Respiration (SCR); or

High Flow Oxygen Therapy (HFOT).

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 19, 2025
From: WOOD, KEVIN N.; LESTAK, TYLER; LUCAS, JACK; ARVIZU-MUNOZ, ENER
To: SAN DIEGO STATE UNIVERSITY (SDSU) FOUNDATION, DBA SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION
Reel/Frame 072489/0394 →
Continuity (3)
Provisional Application 63012632 · Apr 20, 2020
Provisional Application 63005151 · Apr 3, 2020
Related Publication 20230166070A1 · Jun 1, 2023
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