Measuring electrode for ECG epicardial monitoring and measuring system for ECG epicardial monitoring comprising such electrode
The invention relates to a measuring probe for epicardial ECG monitoring comprising the measuring element ( 2 ) for measuring an electric signal from a heart and the connecting element ( 3 ) arranged to output the measured heart signal, the measuring element ( 2 ) being electrically connected with the connecting element ( 3 ). The measuring element ( 2 ) and the connecting element ( 3 ) are layered elements. The invention relates also to a measuring system for epicardial ECG monitoring comprising the probe ( 1 ) connected by the signal cable ( 5 ) with a display device.
1. A measuring probe for epicardial ECG monitoring, comprises a measuring element ( 2 ) for measuring electric signal from a heart, a connecting fragment ( 4 ) and a connecting element ( 3 ) arranged to output the measured heart signal through the connecting fragment ( 4 ), where the measuring element ( 2 ) is electrically connected with the connecting element ( 3 ), and the connecting element ( 3 ) is a layered element containing a conductive layer ( 32 ), a dielectric layer ( 33 ) insulating the conductive layer ( 32 ) and a base layer ( 21 ) extending over the entire surface of the connecting element ( 3 ), characterized in that the measuring element ( 2 ) is a layered element containing a signal-collecting layer ( 22 ) located over at least a part of the measuring element ( 2 ), and the base layer ( 21 ) extending over the entire surface of the measuring element ( 2 ), wherein the signal-collecting layer ( 22 ) of the measuring element ( 2 ) is simultaneously an adhesive layer ( 23 ), which allows to fix the probe ( 1 ) to the heart, wherein the connecting fragment ( 4 ) provided at the end of the connecting element ( 3 ), opposite to the measuring element ( 2 ), is a layered element containing the conductive layer ( 32 ) and the base layer ( 21 ), with a maximum dimension of the measuring element ( 2 ) perpendicular to its thickness being 30 mm,
wherein in the measuring element ( 2 ), the base layer ( 21 ) is located over the signal-collecting layer ( 22 ), and in the connecting element ( 3 ), the base layer ( 21 ) is located over the conductive layer ( 32 ) which is arranged over the dielectric layer ( 33 ), wherein the signal-collecting layer ( 22 ) of the measuring element ( 2 ) and the conductive layer ( 32 ) of the connecting element ( 3 ) constitute a continuous layer extending across the measuring element ( 2 ) and the connecting element ( 3 ).
2. The probe according to claim 1 , characterized in that the measuring element ( 2 ) between the signal-collecting layer ( 22 ) and the base layer ( 21 ) comprises the conductive layer ( 32 ), while in the connecting element ( 3 ), over the dielectric layer ( 33 ), the conductive layer ( 32 ) is arranged, over which the base layer ( 21 ) is located, wherein the conductive layer ( 32 ) of the measuring element ( 2 ) and the conductive layer ( 32 ) of the connecting element ( 3 ) constitute a continuous conductive layer extending across the measuring element ( 2 ) and the connecting element ( 3 ).
3. The probe according to claim 1 , characterized in that in the measuring element ( 2 ), the base layer ( 21 ) is located over the signal-collecting layer ( 22 ), while in the connecting element ( 3 ), over the dielectric layer ( 33 ), the conductive layer ( 32 ) is arranged, over which the base layer ( 21 ) is located, wherein the conductive layer ( 32 ) of the connecting element ( 3 ) at the section adjacent to the measuring element ( 2 ) is made of the same material as the signal-collecting layer ( 22 ) of the measuring element ( 2 ), the remaining portion being made of another conductive material.
4. The probe according to claim 1 , characterized in that the adhesive layer ( 23 ) comprises a polymer and an adhesion promoter.
5. The probe according to claim 1 , characterized in that the conductive layer ( 32 ) in the connecting element ( 3 ) is a graphene layer.
6. The probe according to claim 1 , characterized in that the conductive layer ( 32 ) in the connecting element ( 3 ) is a graphene-PMMA layer comprising graphene and poly(methyl methacrylate) in butyl carbitol acetate.
7. The probe according to claim 1 , characterized in that the signal-collecting layer ( 22 ) in the measuring element ( 2 ) is a graphene layer.
8. The probe according to claim 1 , characterized in that the measuring element ( 2 ) and the connecting element ( 3 ) are located in a same plane.
9. The probe according to claim 1 , characterized in that the dielectric layer ( 33 ) and the base layer ( 21 ) are made of the same material.
10. The probe according to claim 1 , characterized in that the signal-collecting layer ( 22 ) comprises at least one carrier, a conductive substance and at least one adhesion promoter.
11. The probe according to claim 10 , characterized in that the adhesion promoter comprises one substance selected from: lanolin, agar, sodium alginate, collagen, gelatin, and starch and cellulose, and derivatives thereof, carboxymethyl cellulose, carboxymethyl starch, hydroxypropyl starch or a mixture thereof.
12. The probe according to claim 10 , characterized in that the conductive substance is at least one selected from: Au, Ag, PdAg, graphite, graphene, RuO 2 , IrO 2 , Bi 2 Ru 2 O 7 , ITO or a mixture thereof.
13. The probe according to claim 10 , characterized in that the carrier is a polymer compound with a solvent, or a resin with a solvent,
wherein the polymer is one selected from: ethylcellulose, polypropylene, polyethylene, polyesters and polystyrenes, poly(methyl methacrylate) (PMMA), a thermoplastic polyurethane elastomer (TPU), polylactic acid (PLA) or a mixture thereof,
wherein the solvent is one selected from: acetone, dimethylformamide (DMF), butyl carbitol acetate (OKB), chloroform or a mixture thereof.
14. The probe according to claim 1 , characterized in that the base layer ( 21 ) comprises one material selected from: polyethylene terephthalate (PET), polyethylene naphthalate (PEN), polyetheretherketone (PEEK), polycarbonate (PC), polyethersulfone (PES), polarylate (PAR), polycyclic olefin (PCO) or polynorbornene (PNB), polyimide (PI), a fluoric polyester or copolymers thereof.
15. The probe according to claim 1 , characterized in that the thickness of each of the following layers: the dielectric layer ( 33 ), the signal-collecting layer ( 22 ), the connecting layer ( 32 ), is in a range of 10-15 μm.
16. A measuring probe for epicardial ECG monitoring, comprises a measuring element ( 2 ) for measuring electric signal from a heart, a connecting fragment ( 4 ) and a connecting element ( 3 ) arranged to output the measured heart signal through the connecting fragment ( 4 ), where the measuring element ( 2 ) is electrically connected with the connecting element ( 3 ), and the connecting element ( 3 ) is a layered element containing a conductive layer ( 32 ), a dielectric layer ( 33 ) insulating the conductive layer ( 32 ) and a base layer ( 21 ) extending over the entire surface of the connecting element ( 3 ), characterized in that the measuring element ( 2 ) is a layered element containing a signal-collecting layer ( 22 ) located over at least a part of the measuring element ( 2 ), and the base layer ( 21 ) extending over the entire surface of the measuring element ( 2 ), wherein the signal-collecting layer ( 22 ) of the measuring element ( 2 ) is simultaneously an adhesive layer ( 23 ), which allows to fix the probe ( 1 ) to the heart, wherein a connecting fragment ( 4 ) provided at the end of the connecting element ( 3 ), opposite to the measuring element ( 2 ), is a layered element containing the conductive layer ( 32 ) and the base layer ( 21 ), with the maximum dimension of the measuring element ( 2 ) perpendicular to its thickness being 30 mm, and
wherein in the measuring element ( 2 ), the adhesive layer ( 23 ) is a graphene-TPU layer comprising graphene, hydroxypropyl starch and a thermoplastic polyurethane elastomer in dimethylformamide.
17. The probe according to claim 16 , characterized in that the graphene-TPU layer comprises 10% by weight of graphene, 10% by weight of hydroxypropyl starch and 80% of a thermoplastic polyurethane elastomer in dimethylformamide.
18. The probe according to claim 16 , characterized in that the conductive layer ( 32 ) in the connecting element ( 3 ) is a graphene layer.
19. The probe according to claim 16 , characterized in that the signal-collecting layer ( 22 ) in the measuring element ( 2 ) is a graphene layer.
20. The probe according to claim 16 , characterized in that the measuring element ( 2 ) and the connecting element ( 3 ) are located in a same plane.
21. The probe according to claim 16 , characterized in that the signal-collecting layer ( 22 ) comprises at least one carrier, a conductive substance and at least one adhesion promoter.
22. The probe according to claim 21 , characterized in that the adhesion promoter comprises one substance selected from: lanolin, agar, sodium alginate, collagen, gelatin, and starch and cellulose, and derivatives thereof, carboxymethyl cellulose, carboxymethyl starch, hydroxypropyl starch or a mixture thereof.
23. The probe according to claim 21 , characterized in that the conductive substance is at least one selected from: Au, Ag, PdAg, graphite, graphene, RuO 2 , IrO 2 , Bi 2 Ru 2 O 7 , ITO or a mixture thereof.
24. The probe according to claim 21 , characterized in that the carrier is a polymer compound with a solvent, or a resin with a solvent,
wherein the polymer is one selected from: ethylcellulose, polypropylene, polyethylene, polyesters and polystyrenes, poly(methyl methacrylate) (PMMA), a thermoplastic polyurethane elastomer (TPU), polylactic acid (PLA) or a mixture thereof,
wherein the solvent is one selected from: acetone, dimethylformamide (DMF), butyl carbitol acetate (OKB), chloroform or a mixture thereof.
25. The probe according to claim 16 , characterized in that the base layer ( 21 ) comprises one material selected from: polyethylene terephthalate (PET), polyethylene naphthalate (PEN), polyetheretherketone (PEEK), polycarbonate (PC), polyethersulfone (PES), polarylate (PAR), polycyclic olefin (PCO) or polynorbornene (PNB), polyimide (PI), a fluoric polyester or copolymers thereof.
26. The probe according to claim 16 , characterized in that the thickness of each of the following layers: the dielectric layer ( 33 ), the signal-collecting layer ( 22 ), the connecting layer ( 32 ), is in a range of 10-15 μm.