IP Library › Granted Patent US 12,569,369
Granted Patent B2
US 12,569,369 · App. 17/996,814 · Granted Mar 10, 2026

System for laser-based ametropia correction, and method for the alignment thereof

Inventors: Hartmut Vogelsang (Oberweser, DE); Dan Zoltan Reinstein (London, GB); Christian Deutsch (Weimar, DE); Ingo Wundrich (Weimar, DE)
Assignee: Carl Zeiss Meditec AG
A61F9/00804A61F9/00814A61F9/009A61F2009/00846A61F2009/00851A61F2009/00857A61F2009/00872
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,569,369
App. No.
17/996,814
Granted
Mar 10, 2026
Kind
B2
Abstract

A method for aligning a system for laser-based ametropia correction relative to a patient's eye to be treated is disclosed. Predefined pre-operative measurement data which characterize at least predetermined structures of the patient's eye is provided. The predetermined structures include a part of the patient's eye to be treated. In addition, the method includes measuring at least one part of the predetermined structures of the patient's eye using an OCT system immediately before and/or during treatment for ametropia correction of the patient's eye and providing OCT measurement data, and comparing the OCT measurement data and the predefined pre-operative measurement data and preparing comparative data. The method also includes ascertaining a position and/or orientation of the part of the patient's eye to be treated relative to the system and aligning the system relative to the patient's eye using the ascertained position and/or orientation of the part of the patient's eye.

Claims (37)

1 . A method for aligning a system for laser-based vision correction relative to a patient's eye to be treated, the method comprising:

providing specified preoperative measurement data which at least characterize predetermined structures of the patient's eye, the predetermined structures including a portion of the patient's eye to be treated, wherein the provided specified preoperative measurement data are based on a measurement carried out independently of the system for laser-based vision correction;

measuring at least a portion of the predetermined structures of the patient's eye with an Optical Coherence Tomography (OCT) system immediately before and/or during a treatment for vision correction for the patient's eye and providing OCT measurement data;

comparing the OCT measurement data with the specified preoperative measurement data and providing comparison data; and

determining a positioning and/or orientation of the portion of the patient's eye to be treated relative to the system using the comparison data, and aligning the system relative to the patient's eye using the determined position and/or orientation of the portion of the patient's eye to be treated.

2 . The method as claimed in claim 1 , wherein the alignment of the system comprises a centration of the system on a vertex of the patient's eye.

3 . The method as claimed in claim 1 , wherein the alignment of the system comprises a centration of the system on an offset position that deviates from a vertex of the patient's eye and, optionally, a determination of offset coordinates of the offset position.

4 . The method as claimed in claim 3 , wherein the centration of the system on the offset position comprises a calculation of a centration-corrected fluence loss function.

5 . The method as claimed in claim 1 , wherein the system is aligned in manual, partially automated or fully automated fashion.

6 . The method as claimed in claim 1 , wherein the predetermined structures of the patient's eye, which are characterized by the specified preoperative measurement data, and the at least one portion of the predetermined structures of the patient's eye, which is measured by means of the OCT system immediately before and/or during a treatment for vision correction, comprise at least a portion of an anterior chamber of the patient's eye.

7 . The method as claimed in claim 1 , wherein the portion of the patient's eye to be treated comprises at least a portion of a cornea of the patient's eye.

8 . The method as claimed in claim 1 , further comprising:

coupling the patient's eye to a contact interface of the system for laser-based vision correction,

wherein the at least one portion of the predetermined structures of the patient's eye is measured by means of the OCT system at least once before the patient's eye is coupled to the contact interface and at least once after the patient's eye has been coupled to the contact interface.

9 . The method as claimed in claim 1 , further comprising:

verifying the positioning and/or orientation of the portion of the patient's eye to be treated relative to the system with an eye tracker, the verification optionally being implemented continually during at least a part of the treatment for vision correction for the patient's eye.

10 . The method as claimed in claim 9 , further comprising:

referencing an eye position determined with the eye tracker using the OCT measurement data, the determined eye position optionally including, or corresponding to, a pupil position and/or a limbus position.

11 . The method as claimed in claim 1 , wherein the specified preoperative measurement data comprise preoperative OCT measurement data.

12 . The method as claimed in claim 11 , wherein the comparison data comprise a lateral displacement (Δ OCT ) and/or a rotation (Δβ OCT ) and/or a tilt (Δα OCT ) of the OCT measurement data relative to the preoperative OCT measurement data.

13 . The method as claimed in claim 1 , wherein the preoperative measurement data are provided in the form of electronic data.

14 . The method as claimed in claim 1 , wherein the specified preoperative measurement data are retrieved or received via an interface of the system for laser-based vision correction.

15 . The method according to claim 1 , wherein the specified preoperative measurement data are retrieved or received from a database connected to the system for laser-based vision correction.

16 . A system for laser-based vision correction for a patient's eye, the system comprising

an Optical Coherence Tomography (OCT) system for measuring predetermined structures of the patient's eye immediately before and/or during a treatment for vision correction for the patient's eye and for providing OCT measurement data which characterize the measured predetermined structures of the patient's eye; and

a control unit configured to compare the OCT measurement data provided by the OCT system with specified preoperative measurement data and to determine a positioning and/or orientation of a portion of the patient's eye to be treated relative to the system using comparison data from the comparison between the OCT measurement data provided by the OCT system and the specified preoperative measurement data, and to align the system relative to the patient's eye using the determined position and/or orientation of the portion of the patient's eye to be treated;

wherein the provided specified preoperative measurement data are based on a measurement carried out independently of the system for laser-based vision correction.

17 . The system as claimed in claim 16 , further comprising a laser source for providing laser radiation for the treatment, the laser source optionally being configured to emit pulsed laser radiation and the laser source including an excimer laser and/or a picosecond laser and/or a femtosecond laser or being in the form of an excimer laser, picosecond laser and/or femtosecond laser.

18 . The system as claimed in claim 17 , further comprising:

an imaging optical unit for focusing the laser radiation on the cornea of the patient's eye, the imaging optical unit being configured such that the imaging optical unit allows a detection of a back reflection of radiation radiated on the patient's eye by the imaging optical unit and at least partially reflected by the patient's eye, within an acceptance angle χ Max of at least 2.5°.

19 . The system as claimed in claim 18 , wherein the system, and in particular the imaging optical unit, are configured such that the acceptance angle χ Max is greater than 5°.

20 . The system as claimed in claim 18 , wherein the imaging optical unit is in the form of, or comprises, a microscope optical unit.

21 . The system as claimed in claim 18 , wherein the imaging optical unit has an optical opening and a given working distance, a diameter of the optical opening being greater than or equal to the given working distance.

22 . The system as claimed in claim 18 , wherein the imaging optical unit has an optical opening with a diameter of at least 50 mm, and wherein the imaging optical unit has a working distance of less than 50 mm.

23 . The system as claimed in claim 18 , wherein the detection of the back reflection of radiation comprises a detection of a back reflection of an OCT beam radiated into the patient's eye by the imaging optical unit.

24 . The system as claimed in claim 16 , further comprising a contact interface for coupling the patient's eye to the system.

25 . The system as claimed in claim 16 , further comprising an eye tracker for verifying the position and/or orientation of the patient's eye relative to the system, optionally relative to the imaging optical unit.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 29, 2023
From: VOGELSANG, HARTMUT
To: CARL ZEISS MEDITEC AG
Reel/Frame 064108/0985 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 26, 2023
From: REINSTEIN, DAN Z; DEUTSCH, CHRISTIAN; WUNDRICH, INGO
To: CARL ZEISS MEDITEC AG
Reel/Frame 064061/0279 →
Priority Claims (3)
DE 10 2020 206 423.7 · May 24, 2020 · national
DE 10 2020 206 426.1 · May 24, 2020 · national
DE 10 2020 208 676.1 · Jul 10, 2020 · national
Continuity (1)
Related Publication 20230201035A1 · Jun 29, 2023
References Cited (19)
US 9592156B2 · Huang · 2017 [cited by applicant]
US 20050024586A1 · Teiwes · 2005 [cited by examiner]
US 20110040292A1 · Riedel · 2011 [cited by examiner]
US 20130226157A1 · Huang · 2013 [cited by applicant]
US 20150031993A1 · Buckland et al. · 2015 [cited by applicant]
US 20150141972A1 · Woodley · 2015 [cited by examiner]
US 20160095752A1 · Srinivasan · 2016 [cited by examiner]
US 20170189233A1 · Dewey · 2017 [cited by examiner]
WO 2009033111A2 · 2009 [cited by applicant]
WO 2010028663A1 · 2010 [cited by applicant]
Krueger et al.: “Corneal Surface Morphology Following Excimer Laser Ablation With Humidified Gases,” Archives of Ophthalmology, vol. 111, No. 8, pp. 1011-1152, Aug. 1993. [cited by applicant]
Atchison, “Handbook of Visual Optics vol. 1,” Chapter 17, Ed. Pablo Artal, CRC Press Tayler & Francis Group, 2017. [cited by applicant]
International Preliminary Report on Patentability issued in PCT/EP2021/063616, to which this application claims priority, mailed Nov. 17, 2022, and English-language translation thereof. [cited by applicant]
U.S. Appl. No. 17/996,808, filed Oct. 21, 2022, Hartmut Vogelsang, Christian Deutsch, Ingo Wundrich, and Dan Z. Reinstein. [cited by applicant]
Nowakowski et al.: “Investigation of the isoplanatic patch and wavefront aberration along the pupillary axis compared to the line of sight in the eye,” Biomedical Optics Express 240, vol. 3, No. 2, Feb. 1, 2012. [cited by applicant]
International Search Report by the International Searching Authority in PCT/EP2021/063616, to which this application claims priority, mailed Sep. 15, 2021, and English-language translation thereof. [cited by applicant]
Written Opinion by the International Searching Authority in PCT/EP2021/063616, to which this application claims priority, mailed Sep. 15, 2021. [cited by applicant]
Intention to grant issued in EP 21 729 236.6, which is a counterpart hereof, mailed on Oct. 8, 2025, and English-language machine translation thereof. [cited by applicant]
Decision to grant issued in EP 21 729 236.6, which is a counterpart hereof, mailed on May 21, 2025, and English-language machine translation thereof. [cited by applicant]