IP Library Patent Application 18049220
Patent Application
App. No. 18/049,220

SYSTEMS AND METHODS TO PROCESS ELECTRONIC IMAGES FOR DETERMINING TREATMENT

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Patent No.
US None
App. No.
18/049,220
Abstract

A computer-implemented method for processing digital pathology images, the method including receiving a plurality of digital pathology images of at least one pathology specimen, the pathology specimen being associated with a patient. The method may further include determining receiving metadata corresponding to the plurality of digital pathology images, the metadata comprising data regarding previous medical treatment of the patient. Next, the method may include providing the medical images and metadata as input to a machine learning system, the machine learning system having been trained by receiving as input historical treatment information and digital images labeled with a predicted treatment regimen. Lastly, the method may include outputting, by the machine learning system, a treatment effectiveness assessment.

Claims (43)

1 . A computer-implemented method for processing digital pathology images to determine a treatment for one or more patients, comprising:

receiving a plurality of medical images of at least one pathology specimen, the pathology specimen being associated with a patient;

receiving metadata corresponding to the plurality of medical images, the metadata comprising data regarding previous medical treatment of the patient;

providing the medical images and metadata as input to a machine learning system, the machine learning system having been trained by receiving as input historical treatment information and digital images labeled with a predicted treatment regimen; and

outputting, by the machine learning system, a treatment effectiveness assessment.

2 . The method of claim 1 , further comprising:

providing the plurality of medical images and metadata to a trained embedding system capable of outputting a single embedding that may be received by the machine learning system.

3 . The method of claim 2 , the trained embedding system performing steps comprising inferring one or more missing data points to construct a universal embedding, the universal embedding being received by the trained machine learning system.

4 . The method of claim 1 , wherein the trained system outputs the plurality of medical images with marking to display the predicted effects of the treatment effectiveness assessment.

5 . The method of claim 1 , wherein the metadata may further include information describing a tissue type of the pathology specimen for the medical specimen.

6 . The method of claim 1 , further comprising:

inputting the received medical images that correspond to previously treated medical specimen into a second trained system; and

determining a score to measure the effectiveness of past treatment, wherein the score defines a damage of previously healthy slides and additional damage to previously cancerous regions of the inputted slides.

7 . The method of claim 1 , wherein the treatment effectiveness assessment comprises a treatment type and a treatment dosage for the patient.

8 . A system for processing electronic medical images, the system comprising:

at least one memory storing instructions; and

at least one processor configured to execute the instructions to perform operations comprising:

receiving a plurality of medical images of at least one pathology specimen, the pathology specimen being associated with a patient;

receiving metadata corresponding to the plurality of medical images, the metadata comprising data regarding previous medical treatment of the patient;

providing the medical images and metadata as input to a machine learning system, the machine learning system having been trained by receiving as input historical treatment information and digital images labeled with a predicted treatment regimen; and

outputting, by the machine learning system, a treatment effectiveness assessment.

9 . The system of claim 8 , further comprising:

providing the plurality of medical images and metadata to a trained embedding system capable of outputting a single embedding that may be received by the machine learning system.

10 . The system of claim 9 , the trained embedding system performing steps comprising inferring one or more missing data points to construct a universal embedding, the universal embedding being received by the trained machine learning system.

11 . The system of claim 8 , wherein the trained system outputs the plurality of medical images with marking to display the predicted effects of the treatment effectiveness assessment.

12 . The system of claim 8 , wherein the metadata may further include information describing a tissue type of the pathology specimen for the medical specimen.

13 . The system of claim 8 , further comprising:

inputting the received medical images that correspond to previously treated medical specimen into a second trained system; and

determining a score to measure the effectiveness of past treatment, wherein the score defines a damage of previously healthy slides and additional damage to previously cancerous regions of the inputted slides.

14 . The system of claim 8 , wherein the treatment effectiveness assessment comprises a treatment type and a treatment dosage for the patient.

15 . A non-transitory computer-readable medium storing instructions that, when executed by a processor, perform operations processing electronic medical images, the operations comprising:

receiving a plurality of medical images of at least one pathology specimen, the pathology specimen being associated with a patient;

receiving metadata corresponding to the plurality of medical images, the metadata comprising data regarding previous medical treatment of the patient;

providing the medical images and metadata as input to a machine learning system, the machine learning system having been trained by receiving as input historical treatment information and digital images labeled with a predicted treatment regimen; and

outputting, by the machine learning system, a treatment effectiveness assessment.

16 . The computer-readable medium of claim 15 , further comprising:

providing the plurality of medical images and metadata to a trained embedding system capable of outputting a single embedding that may be received by the machine learning system.

17 . The computer-readable medium of claim 16 , the trained embedding system performing steps comprising inferring one or more missing data points to construct a universal embedding, the universal embedding being received by the trained machine learning system.

18 . The computer-readable medium of claim 15 , wherein the trained system outputs the plurality of medical images with marking to display the predicted effects of the treatment effectiveness assessment.

19 . The computer-readable medium of claim 15 , wherein the metadata may further include information describing a tissue type of the pathology specimen for the medical specimen.

20 . The computer-readable medium of claim 15 , further comprising:

inputting the received medical images that correspond to previously treated medical specimen into a second trained system; and

determining a score to measure the effectiveness of past treatment, wherein the score defines a damage of previously healthy slides and additional damage to previously cancerous regions of the inputted slides.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded May 14, 2026
From: ARES CAPITAL CORPORATION, AS COLLATERAL AGENT
To: PAIGE.AI, INC.
Reel/Frame 075589/0752 →
SECURITY INTEREST Recorded Oct 21, 2025
From: PAIGE.AI, INC.
To: ARES CAPITAL CORPORATION, AS COLLATERAL AGENT
Reel/Frame 073216/0876 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 26, 2022
From: KUNZ, JEREMY DANIEL; THIAGARAJAN, DILIP
To: PAIGE.AI, INC.
Reel/Frame 061538/0409 →