IP Library Patent Application 18088354
Patent Application
App. No. 18/088,354

NON-INTRUSIVE DELIVERY MECHANISM FOR PRODUCING PHYSIOLOGICAL EFFECTS IN LIVING ORGANISMS

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Quick Facts
Patent No.
US None
App. No.
18/088,354
Abstract

Systems and methods for producing physiological effects in response to simulated stimuli on living organisms are disclosed herein. In one example, a non-intrusive delivery of drug-simulating signals causes physiological effects on a living organism.

Claims (69)

1 . A method of producing a drug-simulating signal to simulate a physiological effect of a drug on a living organism, the method comprising:

measuring an electrostatic potential associated with a physiological system of the living organism under effect of the drug;

recording the measurement of the electrostatic potential of the physiological system to a memory of a closed system;

generating the drug-simulating signal that is configured based on the recording of the measurement of the electrostatic potential of the physiological system,

wherein the drug-simulating signal is controlled with an amplifier circuit of the closed system, and

wherein the drug-simulating signal includes an electromagnetic signal configured to simulate the effect of the drug on the living organism;

causing the amplifier circuit of the closed system to manipulate the drug-simulating signal based on feedback including measures of electrostatic potentials associated with the physiological system while being radiated with the drug-simulating signal to cause a desired physiological effect;

controlling delivery of the drug-simulating signal in the closed system in response to the feedback and based on a computer program stored in the memory within the closed system; and

responding to the feedback collected by the closed system to dynamically adapt efficacy of the drug-simulating signal toward the desired physiological effect.

2 . The method of claim 1 , wherein the closed system comprises a wearable device, a handheld device, or a combination thereof.

3 . The method of claim 1 , wherein the drug-simulating signal is enhanced by filtering and/or truncating a portion of the drug-simulating signal, wherein the drug-simulating signal causing the physiological effect is filtered through a 6 kHz filter and/or a 7 kHz filter, and wherein the portion causes the physiological effect.

4 . (canceled)

5 . The method of claim 3 , wherein the drug-simulating signal yielding the physiological effect is (1) down-sampled from about 44.1 kHz to 11 kHz or less, and (2) up-sampled to 44.1 kHz.

6 . The method of claim 5 , wherein a low-pass filter and down-sampling removes an unnecessary radio frequency (RF) energy which competes with a frequency responsible for the physiological effect, from being radiated on the living organism during delivery of the drug-simulating signal to cause the physiological effect.

7 . (canceled)

8 . The method of claim 6 , wherein the low-pass filter and down-sampling reduces a file size for the drug-simulating signal.

9 . A method of optimizing a drug-simulating signal based on data obtained following a delivery of the drug-simulating signal to a living organism, the method comprising:

detecting efficacy of a delivered drug-simulating signal to the living organism by:

generating one or more drug-simulating signals to deliver to the living organism;

measuring a physiological effect of the delivered drug-simulating signal on the living organism by a sensor; and

improving the efficacy of the delivered drug-simulating signal to the living organism by a machine learning model comprising:

creating a training dataset from the physiological effect data collected by the sensor;

enabling the drug-simulating signal to make predictions or decisions based on the training dataset; and

adapting dynamically to improve the efficacy of the drug-simulating signal.

10 . The method of claim 9 , wherein improving the efficacy of the delivered drug-simulating signal for producing the physiological effect in the living organism, is performed by a system comprising:

corresponding the drug-simulating signal to an electromagnetic signal that causes the physiological effect;

configuring a simulator to process a recording of an electrostatic potential for a drug and/or other substance collected by the sensor;

communicating the drug-simulating signal between the living organism and the simulator through a communication channel; and

administering a network portal from the simulator comprising an analytics component.

11 . (canceled)

12 . The method of claim 10 , wherein the electrostatic potential is generated from a molecule selected from the group consisting of:

a chemical molecule,

a biochemical molecule, and

a biological molecule.

13 . The method of claim 9 , wherein generating one or more drug-simulating signals to deliver to the living organism is performed by a signal generator.

14 . The method of claim 9 , wherein the sensor measures a physical property of the living organism indicative of the physiological effect of the delivered drug-simulating signal producing in the physiological effect.

15 . (canceled)

16 . The method of claim 14 , wherein the property indicative of the physiological effect of the drug-simulating signal is a temperature of the living organism.

17 . (canceled)

18 . The method of claim 14 , wherein the sensor comprises one or more sensors selected from the group consisting of:

a magnetometer,

a proximity sensor,

a barometer,

a gyroscope, and

an accelerometer.

19 . The method of claim 9 , wherein creating the training dataset from the physiological effect data collected by the sensor to improve the efficacy of the drug-simulating signal is performed by a modeling component.

20 . The method of claim 19 , wherein the modeling component comprises forecasting decisions on the efficacy of the drug-simulating signal.

21 . The method of claim 20 , wherein the forecasting decisions is based on a simulated change by a simulation component.

22 . (canceled)

23 . The method of claim 10 , wherein the analytics component comprises a continuous iterative exploration and investigation of a past performance to forecast a future performance during a different event.

24 .- 29 . (canceled)

30 . A controller to distribute and regulate a drug-simulating signal to a signal generator comprises:

a housing,

a processor,

a memory,

a visual and audio interface, or

any combination thereof.

31 . The controller of claim 30 , wherein the controller further comprises:

a microcontroller circuitry configured to operate the controller, wherein the microcontroller circuitry comprises:

a microprocessor,

a reset circuit, and

a volatile memory; and

a signal generation circuitry configured to drive a coil and cable assembly with the drug-simulating signal, wherein the signal generation circuitry further comprises:

an audio coder-decoder, configured to output an analog output drug-simulating signal;

a programmable output amplifier, configured to receive the analog output drug-simulating signal to the output amplifier; and

a current monitor, configured to determine an electrical characteristic of the coil and cable assembly, and verify that a drug-simulating signal level remains within a specified frequency threshold.

32 .- 38 . (canceled)

39 . The controller of claim 31 , wherein the programmable output amplifier comprises a low-pass filter, and is further configured to adjust an intensity level of an input drug-simulating signal received by a coil of the coil and cable assembly.

40 .- 47 . (canceled)

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 9, 2025
From: FIGUEROA, XAVIER A.; BUTTERS, BENNETT MICHAEL
To: EMULATE THERAPEUTICS, INC.
Reel/Frame 073154/0483 →
SECURITY INTEREST Recorded Sep 16, 2025
From: EMULATE THERAPEUTICS, INC.
To: STREETERVILLE CAPITAL, LLC
Reel/Frame 072271/0459 →