IP Library › Granted Patent US 12,208,003
Granted Patent B2
US 12,208,003 · App. 18/103,671 · Granted Jan 28, 2025

Prosthetic mitral valve

Inventors: Boris Orlov (Haifa, IL); Ehud Raanani (Hod-HaSharon, IL)
Assignee: Sheba Impact Ltd.
A61F2/2409A61F2/2427A61F2/95
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Quick Facts
Patent No.
US 12,208,003
App. No.
18/103,671
Granted
Jan 28, 2025
Kind
B2
Abstract

Apparatus and methods are described herein including an expandable prosthetic mitral valve device that includes a first component configured to be deployed in a left atrium of the subject and a second component configured to be deployed in a left ventricle of the subject. At least one approximating component approximates the first and second components with respect to each other, such that, when the first and said second components are in an approximated configuration with respect to each other, one or more leaflets of the native mitral valve are trapped within the gap between a ventricular part and an annulus part. The approximating component secures the annulus part and the ventricular part in the approximated configuration. Other applications are also described.

Claims (23)

1. An apparatus comprising:

an expandable prosthetic mitral valve device comprising:

a first component configured to be deployed in a left atrium of a subject, the first component comprising an annulus part that is configured for deployment at least partially in a vicinity of a native mitral annulus of the subject;

a second component configured to be deployed in a left ventricle of the subject, the second component including a ventricular part; and

at least one elongate flexible component configured to join the first component to the second component such that:

there is a gap between the ventricular part and the annulus part upon the deployment of the first component and second component,

by sliding, the at least one elongate flexible component brings the first component and second component into an approximated configuration with respect to each other in which the gap is reduced, by pulling the ventricular part toward the annulus part such that the ventricular part at least partially encircles both a portion of the annulus part and one or more leaflets of a native mitral valve of the subject, thereby trapping the leaflets between the ventricular part and the annulus part, and

the at least one elongate flexible component secures the annulus part to the ventricular part in the approximated configuration.

2. The apparatus according to claim 1 , wherein the at least one elongate flexible component comprises a wire configured to slide when pulled.

3. The apparatus according to claim 1 , wherein the first component and/or the second component comprises one or more piercing elements configured to pierce the leaflets of the native mitral valve.

4. The apparatus according to claim 1 , wherein the first component and/or the second component comprises one or more piercing elements configured to pierce tissue surrounding the leaflets of the native mitral valve.

5. The apparatus according to claim 1 , wherein the expandable prosthetic mitral valve device is configured to be deployed in the subject's heart using a transapical approach or a vascular approach.

6. The apparatus according to claim 1 , wherein the expandable prosthetic mitral valve device is configured to be deployed in the subject's heart using a transseptal approach.

7. The apparatus according to claim 1 , wherein the annulus part comprises a valve mechanism suitable for functioning as a prosthetic mitral valve.

8. The apparatus according to claim 1 , wherein the at least one elongate flexible component comprises a first end functionally associated with the annulus part and a second end configured for securing in proximity of an apex of the subject's heart.

9. The apparatus according to claim 1 , wherein the at least one elongate flexible component comprises a first end functionally associated with said ventricular part and a second end configured for securing in proximity of an apex of the subject's heart, wherein the at least one elongate flexible component passes through the annulus part so that a pulling force applied to the second end pulls the ventricular part towards the annulus part.

10. The apparatus according to claim 1 , wherein the annulus part and/or the ventricular part comprises bending mating features that are configured to mate the first and second components to each other.

11. The apparatus according to claim 1 , wherein the elongate flexible component comprises a deployable tether.

12. The apparatus according to claim 1 ,

wherein the apparatus is for use with a deployment device, and

wherein the at least one elongate flexible component comprises a plurality of filaments, each of which is configured to extend from the deployment device such that an end of the filament is secured to the ventricular part and the filament passes through the annulus part.

13. The apparatus according to claim 12 , wherein the plurality of filaments are releasably secured to said ventricular part.

14. The apparatus according to claim 12 , wherein the plurality of filaments are fixedly secured to said ventricular part.

Assignments (2)
CHANGE OF NAME Recorded Dec 23, 2024
From: TEL HASHOMER MEDICAL RESEARCH, INFRASTRUCTURE AND SERVICES LTD.
To: SHEBA IMPACT LTD.
Reel/Frame 069762/0562 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2023
From: ORLOV, BORIS; RAANANI, EHUD
To: TEL HASHOMER MEDICAL RESEARCH, INFRASTRUCTURE AND SERVICES LTD
Reel/Frame 062546/0276 →
Continuity (4)
Continuation 16655656 · Oct 17, 2019
Division 13475994 · May 20, 2012
Provisional Application 61488180 · May 20, 2011
Related Publication 20230172707A1 · Jun 8, 2023
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