Blood sample optimization device
Blood sample optimization systems and methods are described that reduce or eliminate contaminates in collected blood samples, which in turn reduces or eliminates false positive readings in blood cultures or other testing of collected blood samples. A blood sample optimization system can include a blood sequestration device located between a patient needle and a sample needle. The blood sequestration device can include a sequestration chamber for sequestering an initial, potentially contaminated aliquot of blood, and may further include a sampling channel that bypasses the sequestration chamber to convey likely uncontaminated blood between the patient needle and the sample needle after the initial aliquot of blood is sequestered in the sequestration chamber.
1. A device comprising:
an inlet port for receiving a blood sample;
an outlet port;
a chamber connected with the inlet port and the outlet port, and configured to collect a first portion of the blood sample, the chamber including a material that is air permeable and blood impermeable; and
a sampling channel connected with the inlet port and configured to convey a subsequent portion of the blood sample to the outlet port while bypassing the chamber.
2. The device in accordance with claim 1 , wherein the device is configured such that, when a drawing force is applied at the outlet port, blood is drawn into the inlet port and into the chamber.
3. The device in accordance with claim 2 , wherein the device is further configured such that an initial aliquot of blood will contact the material and back up into the chamber.
4. The device in accordance with claim 1 , wherein the material is located at a distal end of the chamber.
5. The device in accordance with claim 1 , wherein the material is a hydrophobic plug.
6. The device in accordance with claim 1 , wherein the material is a hydrophobic membrane.
7. The device in accordance with claim 1 , wherein the material is a hydrophilic membrane.
8. The device in accordance with claim 1 , wherein the sampling channel further comprises a valve configured to close off the sampling channel.
9. The device in accordance with claim 8 , wherein the valve is a clip.
10. The device in accordance with claim 1 , the device further comprising a junction connecting the inlet port and the sampling channel and the chamber.
11. The device in accordance with claim 10 , wherein the junction is configured to convey the subsequent portion of the blood sample to the outlet port while bypassing the chamber.
12. The device in accordance with claim 1 , wherein the chamber has a larger cross-sectional area than the sampling channel.
13. The device in accordance with claim 1 , further comprising a housing that defines the chamber and the sampling channel.
14. The device in accordance with claim 13 , wherein the housing comprises a bottom member mated with a top member, each of the bottom member and the top member defining a part of each of the inlet port, the outlet port, the chamber, and the sampling channel.
15. The device in accordance with claim 1 , further comprising a patient needle and a sample collection device.