mmWave array and implanted susceptors for hyperthermia-based anti-cancer treatments
View Patent ↗Methods and systems for hyperthermia-based anti-cancer treatments are disclosed herein. One disclosed system for hyperthermia-based anti-cancer treatments includes an array of millimeter wave amplifier integrated circuits having an output energy, one or more medical grade implantable susceptors, and a beam steering controller for the array of millimeter wave amplifier integrated circuits that is configured to steer the output energy of the array of millimeter wave amplifier integrated circuits into the one or more medical grade implantable susceptors.
1. A system for hyperthermia-based anti-cancer treatments comprising:
an array of millimeter wave amplifier integrated circuits having an output energy;
one or more medical grade implantable susceptors, the one or more medical grade implantable susceptors including one or more radio frequency transmitters; and
a beam steering controller for the array of millimeter wave amplifier integrated circuits that is configured to steer the output energy of the array of millimeter wave amplifier integrated circuits into the one or more medical grade implantable susceptors, the beam steering controller for the array of millimeter wave amplifier integrated circuits being configured to steer the output energy using information from the one or more radio frequency transmitters.
2. The system of claim 1 , wherein:
the output energy is a total output energy of the array of millimeter wave amplifier integrated circuits;
the beam steering controller for the array of millimeter wave amplifier integrated circuits is configured to steer at least 97% of the total output energy of the array of millimeter wave amplifier integrated circuits into the one or more medical grade implantable susceptors; and
the output energy is millimeter wave energy with a frequency of 30 to 220 gigahertz.
3. The system of claim 2 , wherein:
the array of millimeter wave amplifier integrated circuits is an array of D band amplifiers.
4. The system of claim 1 , wherein:
the output energy is electromagnetic wave energy with frequencies between 20 gigahertz and one terahertz.
5. The system of claim 1 , wherein:
the one or more medical grade implantable susceptors include one or more temperature sensors; and
the beam steering controller for the array of millimeter wave amplifier integrated circuits is configured to adjust the output energy using information from the one or more temperature sensors.
6. The system of claim 5 , wherein:
the one or more medical grade implantable susceptors include one or more wireless inductive power sources for the one or more radio frequency transmitters and the one or more temperature sensors; and
the one or more wireless inductive power sources are configured to charge using the output energy.
7. The system of claim 1 , wherein the one or more medical grade implantable susceptors each comprise:
a susceptor body formed of one of stainless steel and titanium;
a temperature sensor connected to the susceptor body;
a radio frequency transmitter of the one or more radio frequency transmitters, the radio frequency transmitter being connected to the susceptor body;
a wireless inductive power source for the temperature sensor and the radio frequency transmitter; and
a polymer coating for the radio frequency transmitter, temperature sensor, and wireless inductive power source.
8. A hyperthermia-based anti-cancer method comprising:
sub-dermally implanting one or more medical grade implantable susceptors, the one or more medical grade implantable susceptors including one or more radio frequency transmitters;
generating, using an array of millimeter wave amplifier integrated circuits, an output energy;
transmitting information from the one or more radio frequency transmitters to a beam steering controller; and
steering, in a steering step and using the beam steering controller for the array of millimeter wave amplifier integrated circuits, the output energy of the array of millimeter wave amplifier integrated circuits into the one or more medical grade implantable susceptors, wherein steering the output energy uses the information from the one or more radio frequency transmitters.
9. The hyperthermia-based anti-cancer method of claim 8 , further comprising:
generating infrared radiating heat energy at the one or more medical grade implantable susceptors in response to the steering step; and
causing tumor cell denaturation using the infrared radiating heat energy.
10. The hyperthermia-based anti-cancer method of claim 8 , further comprising:
generating convection heat energy at the one or more medical grade implantable susceptors in response to the steering step; and
causing tumor cell denaturation using the convection heat energy.
11. The hyperthermia-based anti-cancer method of claim 8 , wherein:
the output energy is a total output energy of the array of millimeter wave amplifier integrated circuits;
at least 97% of the total output energy of the array of millimeter wave amplifier integrated circuits is steered into the one or more medical grade implantable susceptors in the steering step; and
the output energy is millimeter wave energy with a frequency of 30 to 220 gigahertz.
12. The hyperthermia-based anti-cancer method of claim 11 , wherein:
the array of millimeter wave amplifier integrated circuits is an array of D band amplifiers.
13. The hyperthermia-based anti-cancer method of claim 8 , wherein:
the output energy is electromagnetic wave energy with frequencies between 20 gigahertz and one terahertz.
14. The hyperthermia-based anti-cancer method of claim 8 , further comprising:
minimizing application of the output energy to healthy tissue using the information.
15. The hyperthermia-based anti-cancer method of claim 8 , wherein:
the one or more medical grade implantable susceptors include one or more temperature sensors;
the hyperthermia-based anti-cancer method further comprises transmitting temperature information from the one or more radio frequency transmitters to the beam steering controller; and
the hyperthermia-based anti-cancer method further comprises adjusting the output energy, using the beam steering controller and the temperature information from the one or more radio frequency transmitters.
16. The hyperthermia-based anti-cancer method of claim 15 , further comprising:
targeting one or more target temperatures for the one or more medical grade implantable susceptors during the adjusting.
17. The hyperthermia-based anti-cancer method of claim 8 , wherein:
the one or more medical grade implantable susceptors include one or more temperature sensors;
the hyperthermia-based anti-cancer method further comprises transmitting temperature information from the one or more radio frequency transmitters to the beam steering controller; and
the hyperthermia-based anti-cancer method further comprises steering the output energy, using the beam steering controller and the temperature information from the one or more radio frequency transmitters.
18. The hyperthermia-based anti-cancer method of claim 10 , wherein the one or more medical grade implantable susceptors each comprise:
a susceptor body formed of one of stainless steel and titanium;
a temperature sensor connected to the susceptor body;
a radio frequency transmitter of the one or more radio frequency transmitters, the radio frequency transmitter being connected to the susceptor body;
a wireless inductive power source for the temperature sensor and the radio frequency transmitter; and
a polymer coating for the radio frequency transmitter, temperature sensor, and wireless inductive power source.