Cyclic thiol prodrugs
Disclosed herein are cyclic thiol prodrugs, and pharmaceutical compositions thereof. The prodrugs and pharmaceutical compositions thereof may be used to treat or prevent medical disorders such as, for example, cystinuria, cystinosis, cancer, neurodegenerative disease, Parkinson's disease, Huntington's disease, malaria, nonalcoholic fatty liver disease, radiation poisoning, arsenic poisoning, radioprotection, Wilson's disease or rheumatoid arthritis.
1. A compound having the structure:
2. A pharmaceutical composition comprising the compound of claim 1 and a pharmaceutically acceptable vehicle.
3. A compound having the structure:
4. A pharmaceutical composition comprising the compound of claim 3 and a pharmaceutically acceptable vehicle.
5. A compound having the structure:
6. A pharmaceutical composition comprising the compound of claim 5 and a pharmaceutically acceptable vehicle.