IP Library › Granted Patent US 12,209,159
Granted Patent B2
US 12,209,159 · App. 18/189,277 · Granted Jan 28, 2025

Processable, tunable thiol-ene crosslinked polyurethane shape memory polymers

Inventors: Keith Hearon (Boston, MA); Landon D. Nash (Sunnyvale, CA); Thomas Wilson (San Leandro, CA); Duncan J. Maitland (College Station, TX); Mark A. Wierzbicki (College Station, TX)
Assignees: Lawrence Livermore National Security, LLC; The Texas A&M University System
C08G18/3206C08G18/3212C08G18/6715C08G18/675C08G18/73C08G18/758C08L75/04C08L75/16C08L81/02B29K2105/04
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Quick Facts
Patent No.
US 12,209,159
App. No.
18/189,277
Granted
Jan 28, 2025
Kind
B2
Abstract

An embodiment includes a platform shape memory polymer system. Such an embodiment exhibits a blend of tunable, high performance mechanical attributes in combination with advanced processing capabilities and good biocompatibility. A post-polymerization crosslinking synthetic approach is employed that combines polyurethane and thiol-ene synthetic processes. Other embodiments are described herein.

Claims (31)

1. A method of manufacturing a polyurethane shape memory polymer composition, comprising the steps of:

mixing a polyol monomer with a diisocyanate monomer and trimethylolpropane allyl ether (TMPAE);

initiating polymerization of the polyol and diisocyanate monomers to form a thermoplastic polymer;

blending the thermoplastic polymer with a polythiol crosslinking agent and an initiator dopant; and

initiating crosslinking of the thermoplastic polymer, with at least one of light, heat, or combinations thereof, to form a thermoset polymer.

2. The method of claim 1 comprising fabricating the thermoplastic polymer into a porous structure by at least one of freeze drying, high inverse phase emulsion foaming, physical blowing, pore templating utilizing a solid or liquid pore former, solution spinning, stereolithographic patterning, micro-extrusion or ink pen printing, 3D microdot-based printing, laser machining, electrospinning, cryogelation, supercritical gas foaming, or combinations thereof.

3. The method of claim 1 , wherein:

the initiator dopant is at least one of photoactivated, thermally initiated, or combinations thereof; and

the method comprises irradiating the blended polymer with UV light, heating, or combinations thereof to form the thermoset polymer.

4. The method of claim 3 comprising processing the thermoplastic polymer using at least one of solution casting, solution spinning, dip coating, thermoforming, compression molding, injection molding, extrusion, film blowing, or combinations thereof.

5. The method of claim 4 , wherein the thermoset polymer has a primary shape and the method further comprises:

applying force to the thermoset polymer at a temperature above an actuation transition temperature of the thermoset polymer;

holding the thermoset polymer in a secondary shape at the temperature above the actuation transition temperature; and

cooling the thermoset polymer to a temperature below the actuation transition temperature while the thermoset polymer is in the secondary shape.

6. The method of claim 5 , wherein the thermoset polymer is a foam, the method further comprising axially crimping the foam.

7. The method of claim 4 , wherein the thermoset polymer has shape memory.

8. The method of claim 4 comprising initiating a thiol-ene reaction and forming the thermoset polymer in reaction to the thiol-ene reaction.

9. The method of claim 4 , wherein the thermoset polymer is a poly (thioether-co-urethane).

10. The method of claim 2 , wherein the thermoset polymer includes a poly (thioether-co-ester).

11. The method of claim 4 , wherein the thermoset polymer includes a poly (thioether-co-ester).

12. The method of claim 1 , wherein the diisocyanate monomer includes at least one of Hexamethylene diisocyanate (HDI), trimethylhexamethylene diisocyanate (TMHDI), dicyclohexylmethane 4,4′-diisocyanate (DCHMDI), Isophorone diisocyanate (IPDI), or combinations thereof.

13. The method of claim 12 , wherein the polyol monomer includes at least one of 2-butene-1,4-diol (2-but), diethylene glycol (DEG), diethanolamine (DEA), 4-dimethylaminopyridine (DMAP), allyl alcohol (AA), 3-methyl-1,5-pentanediol (3-MPD), diethylene glycol (DEG), 3 methylpentanediol (3-MPD), 1,4-butanediol (1,4-BD), 2-methylpropanediol (2-MPD), 2,2′-dimethylpropanediol (2,2-DMPD), 1,4-cyclohexanedimethanol (CHDM), or combinations thereof.

14. The method of claim 13 , wherein the polythiol crosslinking agent includes at least one of ethylene glycol bis(3-mercaptopropionate) (EGBMP), dipentaerythritol hexakis(3-mercaptopropionate) (D PHMP), tris [2-(3-mercaptopropionyloxy)ethyl] isocyanurate (3TI), pentaerythritol tetrakis(3-mercaptopropionate) (PETMP), or combinations thereof.

15. The method of claim 1 , wherein the initiator dopant includes a UV photoinitiator.

16. The method of claim 1 comprising initiating crosslinking of the thermoplastic polymer with light.

17. The method of claim 1 comprising initiating crosslinking of the thermoplastic polymer with heat.

18. The method of claim 1 , wherein the initiator dopant is photoactivated and the method comprises irradiating the blended polymer with UV light.

19. The method of claim 1 , wherein the initiator dopant is thermally initiated and the method comprises heating the blended polymer.

20. The method of claim 1 , wherein:

the thermoset polymer includes a proximal portion, a distal portion, and a middle portion coupling the proximal portion to the distal portion;

the initiator dopant is distributed among the proximal, middle, and distal portions.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 26, 2026
From: WILSON, THOMAS
To: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
Reel/Frame 074754/0780 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 26, 2026
From: HEARON, KEITH; NASH, LANDON D.; MAITLAND, DUNCAN J.; WIERZBICKI, MARK A.
To: THE TEXAS A&M UNIVERSITY SYSTEM
Reel/Frame 075626/0140 →
CONFIRMATORY LICENSE Recorded Jul 18, 2024
From: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
To: US DEPARTMENT OF ENERGY
Reel/Frame 068018/0100 →
Continuity (5)
Continuation 16924819 · Jul 9, 2020
Continuation 15548212
Provisional Application 62111233 · Feb 3, 2015
Provisional Application 62144819 · Apr 8, 2015
Related Publication 20230250212A1 · Aug 10, 2023
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