IP Library › Granted Patent US 12,318,091
Granted Patent B2
US 12,318,091 · App. 18/214,676 · Granted Jun 3, 2025

Filamentary devices for treatment of vascular defects

Inventors: Todd J. Hewitt (Laguna Niguel, CA); Brian E. Merritt (San Clemente, CA); William R. Patterson (Huntington Beach, CA)
Assignee: MICROVENTION, INC.
A61B17/12113A61B17/12013A61B17/12031A61B17/12118A61B17/12145A61B17/12172A61B17/12177A61B17/12186A61B2017/00292A61B2017/00526A61B2017/00539A61B2017/00778A61B2017/00862A61B2017/00867A61B2017/1205A61B2017/12068A61B2017/1209A61B2017/12095A61B2090/3966
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Quick Facts
Patent No.
US 12,318,091
App. No.
18/214,676
Granted
Jun 3, 2025
Kind
B2
Abstract

Devices and methods for treatment of a patient's vasculature may include a resilient self-expanding permeable implant having a plurality of elongate filaments secured in a hub at a proximal end of the permeable implant. Each of the plurality of elongate filaments may have a diameter between about 0.0005 and about 0.005 inches. The implant includes at least some filaments consisting of nitinol and at least some composite filaments that are drawn filled tube wires comprising an external nitinol tube and a radiopaque material concentrically disposed within the external tube. The implant has at least about 40% composite filaments relative to a total number of filaments, and wherein a total number of filaments is about 10 to about 300.

Claims (26)

1. A device for treatment of a patient's vasculature, comprising:

a resilient self-expanding permeable implant comprising a plurality of elongate filaments secured in a hub at a proximal end of the permeable implant, wherein the plurality of elongate filaments have a diameter between about 0.0005 inches to about 0.005 inches, the permeable implant comprising at least some filaments consisting of nitinol and at least some composite filaments, the composite filaments comprising drawn filled tube wires each comprising an external nitinol tube and a radiopaque material concentrically disposed within the external tube, and wherein the permeable implant has at least about 40% composite filaments relative to a total number of filaments, and wherein a total number of filaments is about 10 to about 300.

2. The device of claim 1 , wherein the drawn filled tube wires have a fill ratio of cross sectional area selected from the group consisting of between about 10% and about 50%, between about 20% and about 40%, and between about 25% and about 35%.

3. The device of claim 1 , wherein the radiopaque material of the composite filaments comprises a material selected from the group consisting of tantalum, platinum, and gold.

4. The device of claim 1 , wherein each of the composite filaments has a diameter selected from the group consisting of 0.00075″, 0.001″, 0.0015″, and 0.00125″.

5. The device of claim 1 , wherein the permeable shell has an expanded state having a globular configuration.

6. The device of claim 1 , wherein the plurality of elongate filaments are further secured in a distal hub at a distal end of the permeable implant.

7. The device of claim 1 , wherein the total number of filaments is selected from the group consisting of about 70 to about 300, about 10 to about 100, about 60 to about 80, about 100 to about 200, and about 80 to about 180.

8. The device of claim 1 , wherein each filament of the plurality of elongate filaments has a diameter selected from the group consisting of between about 0.0008 inches to about 0.004 inches, between about 0.001 inches to about 0.003 inches, and between about 0.0004 inches to about 0.002 inches.

9. The device of claim 1 , further comprising a tether coupled to the proximal end of the permeable implant, wherein the tether is configured to be releasably coupled to a delivery apparatus.

10. A method for treating a patient's vasculature, comprising the steps of:

advancing a resilient self-expanding permeable implant coupled to a pusher within a catheter to a region of interest within the patient's vasculature,

wherein the permeable implant comprises a plurality of elongate filaments secured in a hub at a proximal end of the permeable implant, wherein each of the plurality of elongate filaments has a diameter between about 0.0005 inches to about 0.005 inches, wherein the permeable implant comprises at least some filaments consisting of nitinol and at least some composite filaments, the composite filaments comprising drawn filled tube wires each comprising an external nitinol tube and a radiopaque material concentrically disposed within the external tube, and wherein the permeable implant has at least about 40% composite filaments relative to a total number of filaments, wherein a total number of filaments is about 10 to about 300;

deploying the permeable implant in the region of interest, wherein the permeable implant expands to an expanded state; and

detaching the permeable implant from the pusher.

11. The method of claim 10 , further comprising the step of withdrawing the catheter from the region of interest after detaching the permeable implant, wherein the permeable implant is in the expanded state after the permeable implant is detached from the pusher.

12. The method of claim 11 , wherein the drawn filled tube wires each have a fill ratio of cross sectional area selected from the group consisting of between about 10% and about 50%, between about 20% and about 40%, and between about 25% and about 35%.

13. The method of claim 11 , wherein the radiopaque material of the composite filaments comprises a material selected from the group consisting of tantalum, platinum, and gold.

14. The method of claim 11 , wherein each of the composite filaments has a diameter selected from the group consisting of 0.00075″, 0.001″, 0.0015″, and 0.00125″.

15. The method of claim 11 , wherein the expanded state has a globular configuration.

16. The method of claim 11 , wherein the plurality of elongate filaments are further secured in a distal hub at a distal end of the permeable implant.

17. The method of claim 11 , wherein the plurality of elongate filaments are secured relative to each other at a proximal end of the permeable implant.

18. The method of claim 11 , wherein the region of interest is a cerebral aneurysm.

19. The method of claim 11 , wherein the region of interest is a vessel.

20. The method of claim 11 , wherein the total number of filaments is selected from the group consisting of about 70 to about 300, about 10 to about 100, about 60 to about 80, about 100 to about 200, and about 80 to about 180.

21. The method of claim 11 , wherein each filament of the plurality of elongate filaments has a diameter selected from the group consisting of between about 0.0008 inches to about 0.004 inches, between about 0.001 inches to about 0.003 inches, and between about 0.0004 inches to about 0.002 inches.

Continuity (9)
Continuation 17028037 · Sep 22, 2020
Continuation 16163287 · Oct 17, 2018
Continuation 15336634 · Oct 27, 2016
Continuation 15071632 · Mar 16, 2016
Continuation 14871352 · Sep 30, 2015
Continuation 14743627 · Jun 18, 2015
Continuation 14459638 · Aug 14, 2014
Provisional Application 61866993 · Aug 16, 2013
Related Publication 20230338035A1 · Oct 26, 2023
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