IP Library Granted Patent US 12,540,991
Granted Patent B2
US 12,540,991 · App. 18/225,556 · Granted Feb 3, 2026

Static and dynamic non-localized efficiency radio frequency shimming for parallel transmission in magnetic resonance imaging

Inventors: Gregory J. Metzger (Minneapolis, MN); Xiaoxuan He (Minneapolis, MN); Simon Schmidt (Minneapolis, MN)
Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
G01R33/543G01R33/4818G01R33/5608
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Quick Facts
Patent No.
US 12,540,991
App. No.
18/225,556
Granted
Feb 3, 2026
Kind
B2
Abstract

A non-localized efficiency shimming technique is used to generate radio frequency (RF) shimming values for imaging with a multi-channel transmit RF coil that minimizes subject-specific imperfections in the transmit magnetic field (B1+) and reduces or eliminates signal dropout in the acquired images, while keeping the coil working in an optimal mode with a high transmit efficiency. The non-localized efficiency shimming can be used for both small and large fields-of-view where a specific ROI does not need to be specified. The static non-localized efficiency shim is advantageous for turbo spin echo (TSE) imaging of smaller anatomical targets, whereas the dynamic non-localized efficiency shim is advantageous for larger fields-of-view, such as in human torsos.

Claims (24)

1 . A method for generating radio frequency (RF) shimming values for use with a magnetic resonance imaging system, the method comprising:

(a) accessing RF transmit sensitivity profile data with a computer system;

(b) generating RF shimming values with the computer system by:

inputting the RF transmit sensitivity profile data to a non-localized efficiency shimming cost function that penalizes under-flipping based on a minimum flip angle tuning parameter; and

optimizing the non-localized efficiency shimming cost function, generating an output as the RF shimming values, wherein the RF shimming values minimize destructive B1+ interferences within an entire imaging field-of-view; and

(c) storing the RF shimming values for use with an MRI system.

2 . The method of claim 1 , wherein the non-localized efficiency shimming cost function further optimizes for maximum flip angle across modes.

3 . The method of claim 1 , wherein optimizing the non-localized efficiency shimming cost function includes setting at least one constraint on the non-localized efficiency shimming cost function while the non-localized efficiency shimming cost function is being optimized.

4 . The method of claim 1 , wherein the non-localized efficiency shimming cost function penalizes under-flipping without explicitly constraining over-flipping.

5 . The method of claim 1 , further comprising:

accessing the RF shimming values with an MRI system;

controlling the MRI system to acquire k-space data using a pulse sequence that implements the RF shimming values; and

reconstructing an image from the k-space data.

6 . The method of claim 5 , wherein the pulse sequence includes a gradient-recalled echo (GRE) acquisition.

7 . The method of claim 1 , wherein the RF transmit sensitivity profile data comprises RF transmit sensitivity profiles for a plurality of subjects and the non-localized efficiency shimming cost function incorporates the RF transmit sensitivity profiles for a plurality of subjects to generate universal modes.

8 . The method of claim 2 , wherein the non-localized efficiency shimming cost function further optimizes for maximum flip angle across modes based in part on a maximum flip angle tuning parameter.

9 . The method of claim 3 , wherein the at least one constraint comprises a constraint for a desired efficiency in a local region-of-interest using a Rayleigh quotient.

10 . The method of claim 3 , wherein the at least one constraint comprises a constraint for local specific absorption rate (SAR) based on virtual observation points.

11 . The method of claim 5 , wherein the pulse sequence includes a spin echo acquisition.

12 . The method of claim 7 , wherein the non-localized efficiency shimming cost function is optimized across the plurality of subjects.

13 . The method of claim 9 , wherein the Rayleigh quotient is used as a starting point for performing a phase-only RF shim.

14 . The method of claim 11 , wherein the spin echo acquisition is a turbo spin echo (TSE) acquisition.

15 . The method of claim 11 , wherein the spin echo acquisition is a fast spin echo (FSE) acquisition.

16 . The method of claim 12 , wherein optimizing the non-localized efficiency shimming cost function across the plurality of subjects includes constructing a plurality of non-localized efficiency shimming cost functions comprises a different non-localized efficiency shimming cost function for each of the plurality of subjects, and minimizing a Euclidian norm of the plurality of non-localized efficiency shimming cost functions.

Assignments (2)
CONFIRMATORY LICENSE Recorded Jan 17, 2024
From: UNIVERSITY OF MINNESOTA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 066339/0591 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 21, 2023
From: METZGER, GREGORY J.; HE, XIAOXUAN; SCHMIDT, SIMON
To: REGENTS OF THE UNIVERSITY OF MINNESOTA
Reel/Frame 065640/0532 →
Continuity (2)
Provisional Application 63369119 · Jul 22, 2022
Related Publication 20240027556A1 · Jan 25, 2024
References Cited (31)
US 20150309132A1 · Brown et al. · 2015 [cited by applicant]
US 20160171670A1 · Koehler · 2016 [cited by examiner]
US 20200011953A1 · Tomi-Tricot et al. · 2020 [cited by applicant]
DE 102006017439B3 · 2007 [cited by examiner]
EP 2461175A1 · 2012 [cited by examiner]
GB 2320579A · 1998 [cited by examiner]
WO WO2011107951A1 · 2011 [cited by examiner]
WO WO2014116986A1 · 2014 [cited by examiner]
JP H1156805 A (Miyoshi) (Year: 1999). [cited by examiner]
Adriany, Gregor, et al. “Transmit and receive transmission line arrays for 7 Tesla parallel imaging.” Magnetic Resonance in Medicine: An Official Journal of the International Society for Magnetic Resonance in Medicine 5… [cited by applicant]
Adriany, Gregor, et al. “A geometrically adjustable 16-channel transmit/receive transmission line array for improved RF efficiency and parallel imaging performance at 7 Tesla.” Magnetic Resonance in Medicine: An Officia… [cited by applicant]
Aigner, Christoph Stefan, et al. “Calibration-free pTx of the human heart at 7T via 3D universal pulses.” Magnetic resonance in medicine 87.1 (2022): 70-84. [cited by applicant]
Brunheim, Sascha, et al. “Fast and accurate multi-channel B1+ mapping based on the TIAMO technique for 7T UHF body MRI.” Magnetic resonance in medicine 79.5 (2018): 2652-2664. [cited by applicant]
Chung, Sohae, et al. “Rapid B1+ mapping using a preconditioning RF pulse with TurboFLASH readout.” Magnetic resonance in medicine 64.2 (2010): 439-446. [cited by applicant]
Cloos, M. A., et al. “KT-points: short three-dimensional tailored RF pulses for flip-angle homogenization over an extended volume.” Magnetic resonance in medicine 67.1 (2012): 72-80. [cited by applicant]
Dietrich, Sebastian, et al. “3D free-breathing multichannel absolute mapping in the human body at 7T.” Magnetic resonance in medicine 85.5 (2021): 2552-2567. [cited by applicant]
Eichfelder, Gabriele, and Matthias Gebhardt. “Local specific absorption rate control for parallel transmission by virtual observation points.” Magnetic resonance in medicine 66.5 (2011): 1468-1476. [cited by applicant]
Gras, V, Vignaud, A, Amadon, A, Le Bihan, D, Boulant, N (2017), Universal pulses: A new concept for calibra on-free parallel transmission. Magn. Reson. Med., 77: 635-643. [cited by applicant]
Grissom, William, et al. “Spatial domain method for the design of RF pulses in multicoil parallel excitation.” Magnetic Resonance in Medicine: An Official Journal of the International Society for Magnetic Resonance in M… [cited by applicant]
He, Xiaoxuan, et al. “Improved TSE imaging at ultrahigh field using nonlocalized efficiency RF shimming and acquisition modes optimized for refocused echoes (AMORE).” Magnetic resonance in medicine 88.4 (2022): 1702-171… [cited by applicant]
Katscher, Ulrich, et al. “Transmit sense.” Magnetic Resonance in Medicine: An Official Journal of the International Society for Magnetic Resonance in Medicine 49.1 (2003): 144-150. [cited by applicant]
Liebert, Andrzej, et al. “Multiple interleaved mode saturation (MIMOSA) for B1+ inhomogeneity mitigation in chemical exchange saturation transfer.” Magnetic resonance in medicine 82.2 (2019): 693-705. [cited by applicant]
Malik, Shaihan J., et al. “Tailored excitation in 3D with spiral nonselective (SPINS) RF pulses.” Magnetic resonance in medicine 67.5 (2012): 1303-1315. [cited by applicant]
Mao W, Smith MB, Collins CM. Exploring the limits of RF shimming for high-field MRI of the human head. Magn Reson Med 2006;56(4):918-922. [cited by applicant]
Metzger, Gregory J., et al. “Dynamically applied B1+ shimming solutions for non-contrast enhanced renal angiography at 7.0 Tesla.” Magnetic resonance in medicine 69.1 (2013): 114-126. [cited by applicant]
Mooiweer, Ronald, et al. “Universal pulses for homogeneous excitation using single channel coils.” Magnetic resonance imaging 92 (2022): 180-186. [cited by applicant]
Orzada, Stephan, et al. RF excitation using time interleaved acquisition of modes (TIAMO) to address B1 inhomogeneity in high-field MRI. Magn Reson Med 2010;64(2):327-333. [cited by applicant]
Orzada, Stephan, et al. “Time-interleaved acquisition of modes: an analysis of SAR and image contrast implications.” Magn Reson Med 67.4 (2012): 1033-1041. [cited by applicant]
Saekho S, Yip CY, Noll DC, Boada FE, Stenger VA. Fast-kz three-dimensional tailored radiofrequency pulse for reduced B1 inhomogeneity. Magn Reson Med 2006;55(4):719-724. [cited by applicant]
Setsompop, K., L. L. Wald, and E. Adalsteinsson. “Reduced-voltage RF shimming for adiabatic pulse design in parallel transmission.” Proceedings of the 15th Scientific Meeting, ISMRM. Berlin. 2007, 1 page. [cited by applicant]
Van de Moortele, Pierre-François, et al. “B1 destructive interferences and spatial phase patterns at 7 T with a head transceiver array coil.” Magnetic resonance in medicine 54.6 (2005): 1503-1518. [cited by applicant]