IP Library Granted Patent US 12,324,629
Granted Patent B2
US 12,324,629 · App. 18/298,077 · Granted Jun 10, 2025

Method for determination of surgical procedure access

Inventors: Frank D'Amelio (San Clemente, CA); Gianluca Parrini (Cascina, IT); Leonardo Manetti (Montevarchi, IT); Damiano Fortuna (Montevarchi, IT); Denis Mattia De Micheli (Navacchio di Cascina, IT)
Assignee: EPICA INTERNATIONAL, INC.
A61B34/10A61B34/30G06T17/20A61B2034/105A61B2034/107A61B2090/3762G06T2210/41
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Quick Facts
Patent No.
US 12,324,629
App. No.
18/298,077
Granted
Jun 10, 2025
Kind
B2
Abstract

A method for assisting in the performance of a surgical procedure on a patient is disclosed. The method includes receiving an intra-operative CT scan image, generating a three-dimensional isotropic scaffold based on the intra-operative CT scan image, fusing one or more images with the three-dimensional isotropic scaffold to form a three-dimensional model of a portion of the body of the patient, receiving information regarding the surgical procedure, determining obstacles in the path of the surgical procedure, and determining possible trajectories for the surgical procedure. The received information includes information regarding a surgical target to be operated upon, a region of access on the skin of the patient, and a surgical instrument to be used during the surgical procedure.

Claims (14)

1. A method for performing a surgical procedure on a patient, comprising:

generating a three-dimensional model of a portion of the body of the patient; and

guiding a surgical instrument within the body of the patient based on the model and real-time feedback obtained by monitoring the surgical procedure using fluoroscopy,

wherein generating the three-dimensional model comprises determining obstacles in the path of the surgical procedure by modeling light rays from a surgical target to a region of surgical access on the skin of the patient.

2. The method of claim 1 , wherein said determining obstacles in the path of the surgical procedure comprises receiving information regarding the surgical procedure.

3. The method of claim 2 , wherein, in said receiving information regarding the surgical procedure, the information includes information regarding a surgical target to be operated upon, a region of access on the skin of the patient, and a surgical instrument to be used during the surgical procedure.

4. The method of claim 1 , wherein said generating the three-dimensional model comprises:

receiving an intra-operative CT scan image;

generating a three-dimensional isotropic scaffold based on the intra-operative CT scan image; and

fusing one or more images with the three-dimensional isotropic scaffold.

5. The method of claim 4 , further comprising fusing the three-dimensional isotropic scaffold with at least one non-intra-operative CT image selected from the group consisting of a pre-operative CT image, a pre-operative MRI image, a pre-operative ultrasound image, a pre-operative SPECT image, a pre-operative PET image, and an intra-operative ultrasound image.

6. The method of claim 4 , wherein the three-dimensional isotropic scaffold comprises isotropic voxels.

7. The method of claim 4 , wherein said fusing of said one or more images with the three-dimensional isotropic scaffold reduces distortions.

8. The method of claim 4 , wherein said fusing of said one or more images with the three-dimensional isotropic scaffold creates a multi-modality anatomic model.

Assignments (3)
INTELLECTUAL PROPERTY SECURITY INTEREST AGENT AGREEMENT Recorded Mar 13, 2026
From: AVENUE VENTURE OPPORTUNITIES FUND, L.P.
To: QUANTUM SCAN HOLDINGS, INC.
Reel/Frame 075093/0287 →
SECURITY INTEREST Recorded Sep 5, 2024
From: EPICA INTERNATIONAL, INC.; EPICA MEDICAL INNOVATIONS LLC
To: AVENUE VENTURE OPPORTUNITIES FUND, L.P., AS AGENT
Reel/Frame 068503/0757 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 10, 2023
From: D'AMELIO, FRANK; PARRINI, GIANLUCA; MANETTI, LEONARDO; FORTUNA, DAMIANO; DE MICHELI, DENIS MATTIA
To: EPICA INTERNATIONAL, INC.
Reel/Frame 063282/0192 →
Continuity (4)
Division 17480107 · Sep 20, 2021
Division 16275313 · Feb 13, 2019
Provisional Application 62630612 · Feb 14, 2018
Related Publication 20230248436A1 · Aug 10, 2023
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