Granted Patent B2

US 12,232,810 · App. 18/317,549 · Granted Feb 25, 2025

Inventors: Ryo Kubota (Seattle, WA); Stephan Wyder (Bern, CH); Philip M. Buscemi (Mount Pleasant, SC); Matthias Pfister (Liebefeld-Bern, CH); Alexander Holzer (Bern, CH)

Assignee: ACUCELA INC.

A61B3/102A61B3/1225G01B9/02004G01B9/02091

Abstract

Claims (14)

1. An optical coherence tomography (OCT) system to measure a tissue layer of an eye, comprising:

an OCT interferometer comprising a light source to generate a measurement beam, a scanner for moving the measurement beam on the tissue layer in a scan pattern, a plurality of optical elements, and a detector; and

a processor operatively coupled to the scanner and configured to execute instructions to cause the scanner to move the measurement beam on the tissue layer in the scan pattern, wherein the scan pattern comprises a plurality of lobes;

wherein the scanner comprises a mirror configured to pivot about a first pivot axis and a second pivot axis transverse to the first pivot axis to move the measurement beam along the scan pattern;

wherein the scanner comprises a first resonance frequency for rotation of the mirror about the first pivot axis and a second resonance frequency for rotation of the mirror about the second pivot axis, the first resonance frequency different from the second resonance frequency by at least about 25%.

2. The OCT system of claim 1 , wherein the scan pattern comprises a rose curve.

3. The OCT system of claim 1 , wherein said plurality of lobes corresponds to a radial scan.

4. The OCT system of claim 1 , wherein the scan pattern includes between four (4) and twenty-four (24) lobes.

5. The OCT system of claim 1 , wherein the processor is configured with instructions to generate a plurality of A-scans of the tissue layer with each A-scan comprising the scanner moving the measurement beam along each of the plurality of lobes of the scan pattern, and wherein a sampling rate of the plurality of A-scans is within a range from 10 kHz to 50 kHz.

6. The OCT system of claim 5 , wherein an emitted wavelength varies in response to one or more of heating, a change of index, or an increase of length of a laser gain medium.

7. The OCT system of claim 1 , wherein a position of the mirror is altered by an application of an electrostatic force.

8. The OCT system of claim 1 , wherein the light source comprises a swept light source configured to vary an emitted wavelength.

9. The OCT system of claim 8 , wherein the swept light source comprises a vertical cavity surface emitting laser (VCSEL).

10. The OCT system of claim 1 , wherein the mirror of the scanner moves continuously with one or more rotations corresponding to a trajectory of the scan pattern and a swept source VCSEL turns on and off with a frequency in relation to a size of the measurement beam and a velocity of the measurement beam on the tissue layer such that a plurality of A-scans of the measurement beam overlap.

Assignments (1)

Continuity (5)

References Cited (400)