Compounds and compositions for treating conditions associated with LPA receptor activity
The present disclosure provides LPA antagonists, as well as pharmaceutical compositions comprising the compounds disclosed herein. Also provided are methods for treating LPA-associated diseases, disorders, and conditions.
1. A compound which is:
or a pharmaceutically acceptable salt thereof.
2. A pharmaceutical composition comprising a compound of claim 1 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
3. A compound which is:
or a pharmaceutically acceptable salt thereof.
4. A pharmaceutical composition comprising a compound of claim 3 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
5. A compound, which is:
or a pharmaceutically acceptable salt thereof.
6. A compound, which is:
or a pharmaceutically acceptable salt thereof.
7. A compound, which is:
or a pharmaceutically acceptable salt thereof.
8. A compound, which is:
or a pharmaceutically acceptable salt thereof.
9. A compound, which is:
or a pharmaceutically acceptable salt thereof.
10. A compound, which is:
or a pharmaceutically acceptable salt thereof.
11. A compound, which is:
or a pharmaceutically acceptable salt thereof.
12. A compound, which is:
or a pharmaceutically acceptable salt thereof.
13. A compound, which is:
or a pharmaceutically acceptable salt thereof.
14. A compound, which is:
or a pharmaceutically acceptable salt thereof.
15. A pharmaceutical composition comprising a compound of claim 5 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
16. A pharmaceutical composition comprising a compound of claim 6 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
17. A pharmaceutical composition comprising a compound of claim 7 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
18. A pharmaceutical composition comprising a compound of claim 8 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
19. A pharmaceutical composition comprising a compound of claim 9 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
20. A pharmaceutical composition comprising a compound of claim 10 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
21. A pharmaceutical composition comprising a compound of claim 11 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
22. A pharmaceutical composition comprising a compound of claim 12 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
23. A pharmaceutical composition comprising a compound of claim 13 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
24. A pharmaceutical composition comprising a compound of claim 14 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
25. A compound, which is:
26. A compound, which is:
27. A compound, which is:
28. A compound, which is:
29. A compound, which is:
30. A compound, which is:
31. A compound, which is:
32. A compound, which is:
33. A compound, which is:
34. A compound, which is: