IP Library Granted Patent US 12,053,646
Granted Patent B2
US 12,053,646 · App. 18/329,129 · Granted Aug 6, 2024

Artificial intelligence modeling for radiation therapy dose distribution analysis

Inventors: Jarkko Peltola (Helsinki, FI); Marko Rusanen (Helsinki, FI); Ville Pietila (Helsinki, FI)
Assignee: SIEMENS HEALTHINEERS INTERNATIONAL AG
A61N5/1031G06N3/08A61N2005/1041A61N2005/1074
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Quick Facts
Patent No.
US 12,053,646
App. No.
18/329,129
Granted
Aug 6, 2024
Kind
B2
Abstract

Disclosed herein are methods and systems to optimize a radiation therapy treatment plan using dose distribution values predicted via a trained artificial intelligence model. A server trains the AI model using a training dataset comprising data associated with a plurality of previously implemented radiation therapy treatments on a plurality of previous patients and dose distributions associated with one or more organs of each previous patient. The server then executes the trained AI model to predict dose distribution for a patient. The server then displays a heat map illustrating the predicted values, transmits the predicted values to a plan optimizer to generate an optimized treatment plan for the patient, and/or transmits an alert when a treatment plan generated by a plan optimizer deviates from rules and thresholds indicated within the patient's plan objectives.

Claims (35)

1. A method comprising:

calculating, by a processor, a dose distribution value for an anatomical region of a patient; and

displaying, by the processor, a heat map having a set of segments where each segment corresponds to a first coordinate and a second coordinate of the anatomical region of the patient,

wherein a visual attribute of each segment corresponds to the calculated dose distribution value, and

wherein at least one segment corresponding to a first region exceeding a first threshold or a second region below a second threshold is visually distinct from other segments within the heat map.

2. The method of claim 1 , wherein the dose distribution value is calculated using an artificial intelligence model, wherein the artificial intelligence model is trained using a training dataset comprising data associated with a plurality of previously implemented radiation therapy treatments on a plurality of previous patients and dose distributions associated with one or more organs of each previous patient.

3. The method of claim 2 , wherein the artificial intelligence model uses a treatment plan associated with the patient to identify the dose distribution value associated with the anatomical region of the patient.

4. The method of claim 1 , wherein at least one of the first threshold or the second threshold is retrieved from a plan objective associated with the patient.

5. The method of claim 1 , further comprising:

displaying, by the processor, an input element configured to receive an acceptance or rejection of at least one of the first region or the second region.

6. The method of claim 1 , further comprising:

transmitting, by the processor, data associated with at least one of first region or the second region to a plan optimizer application.

7. The method of claim 1 , wherein the visual attribute of each segment corresponds to a color, a shading, or a visual pattern.

8. A computer system comprising:

a server comprising at least one processor and a non-transitory computer-readable medium containing instructions that when executed by the at least one processor causes the processor to perform operations comprising:

calculate a dose distribution value for an anatomical region of a patient; and

display a heat map having a set of segments where each segment corresponds to a first coordinate and a second coordinate of the anatomical region of the patient, wherein a visual attribute of each segment corresponds to the calculated dose distribution value, and wherein at least one segment corresponding to a first region exceeding a first threshold or a second region below a second threshold is visually distinct from other segments within the heat map.

9. The computer system of claim 8 , wherein the dose distribution value is calculated using an artificial intelligence model, wherein the artificial intelligence model is trained using a training dataset comprising data associated with a plurality of previously implemented radiation therapy treatments on a plurality of previous patients and dose distributions associated with one or more organs of each previous patient.

10. The computer system of claim 9 , wherein the artificial intelligence model uses a treatment plan associated with the patient to identify the dose distribution value associated with the anatomical region of the patient.

11. The computer system of claim 8 , wherein at least one of the first threshold or the second threshold is retrieved from a plan objective associated with the patient.

12. The computer system of claim 8 , wherein the instructions further cause the processor to:

display an input element configured to receive an acceptance or rejection of at least one of the first region or the second region.

13. The computer system of claim 8 , wherein the instructions further cause the processor to:

transmit data associated with at least one of first region or the second region to a plan optimizer application.

14. The computer system of claim 8 , wherein the visual attribute of each segment corresponds to a color, a shading, or a visual pattern.

15. A non-transitory machine-readable storage medium having computer-executable instructions stored thereon that, when executed by one or more processors, cause the one or more processors to perform operations comprising:

calculate a dose distribution value for an anatomical region of a patient; and

display a heat map having a set of segments where each segment corresponds to a first coordinate and a second coordinate of the anatomical region of the patient, wherein a visual attribute of each segment corresponds to the calculated dose distribution value, and wherein at least one segment corresponding to a first region exceeding a first threshold or a second region below a second threshold is visually distinct from other segments within the heat map.

16. The non-transitory machine-readable storage medium of claim 15 , wherein the dose distribution value is calculated using an artificial intelligence model, wherein the artificial intelligence model is trained using a training dataset comprising data associated with a plurality of previously implemented radiation therapy treatments on a plurality of previous patients and dose distributions associated with one or more organs of each previous patient.

17. The non-transitory machine-readable storage medium of claim 16 , wherein the artificial intelligence model uses a treatment plan associated with the patient to identify the dose distribution value associated with the anatomical region of the patient.

18. The non-transitory machine-readable storage medium of claim 15 , wherein at least one of the first threshold or the second threshold is retrieved from a plan objective associated with the patient.

19. The non-transitory machine-readable storage medium of claim 15 , wherein the instructions are further configured to:

display an input element configured to receive an acceptance or rejection of at least one of the first region or the second region.

20. The non-transitory machine-readable storage medium of claim 15 , wherein the instructions are further configured to:

transmit data associated with at least one of first region or the second region to a plan optimizer application.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 5, 2023
From: PELTOLA, JARKKO; RUSANEN, MARKO; PIETILA, VILLE
To: VARIAN MEDICAL SYSTEMS, INC.
Reel/Frame 063854/0915 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 5, 2023
From: VARIAN MEDICAL SYSTEMS, INC.
To: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG
Reel/Frame 063855/0050 →
MERGER AND CHANGE OF NAME Recorded Jun 5, 2023
From: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG; SIEMENS HEALTHINEERS INTERNATIONAL AG
To: SIEMENS HEALTHINEERS INTERNATIONAL AG
Reel/Frame 063861/0395 →
Continuity (2)
Continuation 17208748 · Mar 22, 2021
Related Publication 20230310890A1 · Oct 5, 2023