Device and method for intravascular imaging and sensing
An intravascular sensor device can be used to guide treatment of a diseased blood vessel in the body of a patient. In some examples, the intravascular sensor device includes a pressure sensor and an ultrasound transducer. The intravascular sensor device is used to measure a pressure within the diseased blood vessel and acquire an ultrasound image of the diseased blood vessel. The pressure may be measured during hyperemic blood flow that is caused by a pharmacologic vasodilator drug. The measured pressure can be used to calculate a fractional flow reserve value. The ultrasound image can be used to determine a physical dimension of the blood vessel, such as cross-sectional area. The fractional flow reserve value and physical dimensions of the blood vessel can be used to optimize patient treatment.
1. A sensing catheter for insertion into a blood vessel, the sensing catheter comprising:
a first portion including:
a lumen structured for receiving a guide wire having an outer diameter of 0.014 inches; and
a sensor assembly surrounding the lumen, the sensor assembly including:
at least one ultrasound transducer array; and
a pressure sensor; and
a second portion extending from a proximal end of the first portion, the second portion including the lumen, and the second portion housing a flexible circuit assembly connected to the sensor assembly, wherein the second portion has an outer diameter less than an outer diameter of the first portion, and wherein the outer diameter of the second portion is 0.023 inches or less.
2. The sensing catheter of claim 1 , wherein the at least one ultrasound transducer array and the pressure sensor are positioned on a substrate.
3. The sensing catheter of claim 1 , wherein the sensor assembly includes a set of sensor subassemblies positioned around the lumen, and the flexible circuit assembly further includes flexible circuit arms each connected to a sensor subassembly of the set of sensor subassemblies.
4. The sensing catheter of claim 1 , wherein the lumen has an inner diameter of about 0.0165 inches.
5. The sensing catheter of claim 1 , wherein the lumen includes a material that reduces friction between the lumen and the guide wire.
6. The sensing catheter of claim 5 , wherein the material includes polytetrafluoroethylene (PTFE).
7. The sensing catheter of claim 1 , wherein the first portion includes a side port for the sensor assembly to acquire a measurement of the blood vessel.