IP Library Granted Patent US 12,193,864
Granted Patent B2
US 12,193,864 · App. 18/330,502 · Granted Jan 14, 2025

Method for determining a property of an object and associated device

Inventors: Jean Provost (Paris, FR); Anikitos Garofalakis (Paris, FR); Mathieu Pernot (Paris, FR); Mickaël Tanter (Paris, FR); Bertrand Tavitian (Paris, FR); Thomas Viel (Paris, FR)
Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE; SORBONNE UNIVERSITE; UNIVERSITÉ PARIS CITÉ; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS); ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS; ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
A61B6/5247A61B6/032A61B6/037A61B6/4258A61B6/4417A61B8/06A61B8/4416A61B8/488A61B8/5261A61N7/00
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Quick Facts
Patent No.
US 12,193,864
App. No.
18/330,502
Granted
Jan 14, 2025
Kind
B2
Abstract

The invention relates to a method for determining at least one property of an object, the method comprising a step of: a) obtaining first data relative to the object by an ultrasound imaging technique imaging the object at a frame rate superior to 300 Hz, characterized in that the method further comprises a step of: b) obtaining second data relative to the object by imaging the object with at least one of a X-ray and a γ-ray, and c) determining the at least one property of the object based on the first data and the second data.

Claims (40)

1. A method for determining at least one property of an object, the method comprising steps of:

a) obtaining first data relative to the object by imaging the object according to a first imaging modality, the first imaging modality being an ultrasound imaging technique imaging the object at a frame rate superior to 300 Hz with ultrasound waves, wherein the first imaging modality is carried out with an ultrasound probe which is maintained in a stable position using a support and without an operator holding the ultrasound probe or support, and wherein at least one of the following properties is fulfilled for the first imaging modality:

the first imaging modality comprises applying unfocused ultrasound waves,

the first imaging modality comprises applying multiple ultrasound plane waves simultaneously,

the ultrasound imaging technique is chosen from a group consisting of functional ultrasound imaging, electromechanical wave imaging, shear-wave imaging, three-dimensional ultrafast ultrasound imaging, and four-dimensional ultrafast ultrasound imaging,

b) obtaining second data relative to the object by imaging the object according to a second imaging modality based on detection of rays, each detected ray being an X-ray or a γ-ray,

c) determining the at least one property of the object based on the first data and the second data,

d) evaluating an attenuation of at least one of the detected γ-rays by the ultrasound waves, and

e) compensating the evaluated attenuation by using a computed tomography technique,

wherein images are obtained at step b), the first data being a movement of the object, and wherein step c) comprises correcting the images obtained at step b) based on the first data, to obtain reconstructed images.

2. The method according to claim 1 , wherein the support is displaceable.

3. The method according to claim 1 , wherein the support is a rod maintained by a positioner.

4. The method according to claim 1 , wherein step a) comprises displacing the ultrasound probe in function of a movement of the object from one image to another image.

5. The method according to claim 1 , wherein step a) further comprises displacing the ultrasound probe in function of hemodynamics data.

6. The method according to claim 1 , wherein at step b), at least one of the following properties is fulfilled:

step b) is carried out by using a computed tomography technique;

step b) is carried out by using a γ-scintigraphy technique;

step b) is carried out by using a positron emission tomography technique;

γ-rays are detected, the detection of γ-ray being in coincidence; and

step a) being carried out at a first plurality of time instants, step b) is carried out at a second plurality of time instants, and wherein at least one time instant of the first plurality being equal to one time instant of the second plurality.

7. The method according to claim 1 , wherein step b) and step e) are carried out simultaneously.

8. The method according to claim 1 , wherein the object is a biological object studied and the determined properties enables achieving an angiography of the object.

9. A device for determining at least one property of an object, the device comprising:

a first imager adapted to image an object according to a first imaging modality, the first imaging modality being an ultrasound imaging technique imaging the object at a frame rate superior to 300 Hz with ultrasound waves, the first imager comprising an ultrasound probe configured to carry out the first imaging modality and a support configured to maintain the ultrasound probe in a stable position without an operator holding the ultrasound probe or support, wherein at least one of the following properties is fulfilled for the first imaging modality:

the first imaging modality comprises applying unfocused ultrasound waves,

the first imaging modality comprises applying multiple ultrasound plane waves simultaneously, and

the ultrasound imaging technique is chosen from a group consisting of functional ultrasound imaging, electromechanical wave imaging, shear-wave imaging, three-dimensional ultrafast ultrasound imaging, and four-dimensional ultrafast ultrasound imaging,

a controller adapted to control the first imager to obtain first data relative to the object, wherein the first data is a movement of the object based on images obtained with the first imager, and

a second imager adapted to image the object according to a second imaging modality based on the detection of rays, each detected ray being an X-ray or a γ-ray,

the controller being further adapted to control the second imager to obtain second data relative to the object,

the controller being further adapted to determine the at least one property of the object based on the first data and the second data, wherein the controller is adapted to correct images obtained with the second imager based on the first data to obtain reconstructed images,

the device being further adapted to evaluate an attenuation of at least one of the detected γ-rays by the ultrasound waves, and compensate the evaluated attenuation by using a computed tomography technique.

10. The device according to claim 9 , wherein the second imager is a computed tomography imager or a γ-scintigraphy imager.

11. A method for treating a disease of an area of a subject, the method comprising the steps of:

applying ultrasound waves in a continuous way on the area to be treated, the step of applying being carried out with an ultrasound probe which is maintained in a stable position using a support and without the operator holding the ultrasound probe or support,

imaging the area of the subject according to a modality based on detection of rays, each detected ray being an X-ray or a γ-ray, to obtain images,

correcting the images obtained during the imaging step based on data related to a movement over the area to be treated in the applying step to obtain reconstructed images,

using the images to control the application of the ultrasound waves,

evaluating an attenuation of at least one of the detected γ-rays by the ultrasound waves, and

compensating the evaluated attenuation by using a computed tomography technique.

Assignments (3)
MERGER AND CHANGE OF NAME Recorded Mar 25, 2024
From: UNIVERSITE PARIS DESCARTES; UNIVERSITÉ PARIS DIDEROT - PARIS 7; UNIVERSITE DE PARIS
To: UNIVERSITE DE PARIS
Reel/Frame 066888/0673 →
CHANGE OF NAME Recorded Mar 25, 2024
From: UNIVERSITE DE PARIS
To: UNIVERSITÉ PARIS CITÉ
Reel/Frame 066888/0729 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 21, 2023
From: PROVOST, JEAN; GAROFALAKIS, ANIKITOS; PERNOT, MATHIEU; TANTER, MICKAEL; TAVITIAN, BERTRAND; VIEL, THOMAS
To: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM); SORBONNE UNIVERSITE; UNIVERSITE PARIS DIDEROT - PARIS 7; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS; UNIVERSITE PARIS DESCARTES; ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS
Reel/Frame 064341/0749 →
Priority Claims (1)
EP 15306533 · Sep 29, 2015 · regional
Continuity (2)
Continuation 15763938
Related Publication 20230309944A1 · Oct 5, 2023
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