IP Library › Granted Patent US 12,714,704
Granted Patent B2
US 12,714,704 · App. 18/370,069 · Granted Aug 25, 2026

Cleavable conjugates of catechol compounds and water-soluble polymers and methods of treatment using the same

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Quick Facts
Patent No.
US 12,714,704
App. No.
18/370,069
Granted
Aug 25, 2026
Kind
B2
Assignments (2)
CHANGE OF NAME Recorded Apr 12, 2024
From: SERINA THERAPEUTICS, INC.
To: SERINA THERAPEUTICS (AL), INC.
Reel/Frame 067087/0743 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 19, 2023
From: FANG, ZHIHAO; WEIMER, REBECCA; VIEGAS, TACEY; BENTLEY, MICHAEL; MOREADITH, RANDALL
To: SERINA THERAPEUTICS, INC.
Reel/Frame 064953/0905 →
Continuity (4)
Continuation 17263723
Provisional Application 62711427 · Jul 27, 2018
Provisional Application 62788790 · Jan 5, 2019
Related Publication 20240016798A1 · Jan 18, 2024
References Cited (20)
US 5624677A · El-Rashidy et al. · 1997 [cited by applicant]
US 8383093B1 · Moreadith · 2013 [cited by examiner]
US 8597633B2 · Moreadith et al. · 2013 [cited by applicant]
US 10314837B2 · Moreadith · 2019 [cited by examiner]
US 10426768B2 · Moreadith · 2019 [cited by examiner]
US 11224595B2 · Moreadith · 2022 [cited by examiner]
US 11298350B2 · Moreadith · 2022 [cited by examiner]
US 11766432B2 · Bentley · 2023 [cited by examiner]
US 11944618B2 · Moreadith · 2024 [cited by examiner]
US 20150246958A1 · Han · 2015 [cited by applicant]
US 20160303250A1 · Moreadith et al. · 2016 [cited by applicant]
WO 2013067199 · 2013 [cited by applicant]
WO 2020264505 · 2020 [cited by applicant]
Apomorphine. PubChem. Retrieved from the Internet on Oct. 6, 2024, https://pubchem.ncbi.nlm.nih.gov/compound/Apomorphine#section=2D-Structure. (Year: 2024). [cited by examiner]
Seeman P, Guan HC. Dopamine D1 and D2 receptors are sensitive to the cationic form of apomorphine. Mol Pharmacol. Dec. 1987; 32(6):760-3. PMID: 2961976. (Year: 1987). [cited by examiner]
Extended European Search Report dated Nov. 22, 2022 of corresponding European Patent Application No. 19841823.8. [cited by applicant]
Baldessarini, Ross J. et al., “Hydrolysis of Diester Prodrugs of Apomorphine”, Biochemical Pharmacology, vol. 26, pp. 1749-1756, 1977. [cited by applicant]
Di Stefano A, Sozio P, Cerasa L.S. Antiparkinson prodrugs, Molecules, Jan. 16, 2008;13(1):46-68, doi: 10.3390/molecules 13010046. PMID: 18259129; PMCID: PMC6244951. (Year: 2008). [cited by applicant]
Ashenhurst, J. Nucleophiles and Electrophiles, Master Organic Chemistry, Published Dec. 20, 2019, Retrieved from the internet on Jul. 20, 2022, https://www.studocu.com/row/document/jamaa%D8% A9-alkof%D8%A9/microelectron… [cited by applicant]
Young, Lee, “International Search Report and Written Opinion for PCT/US2019/043820” International Searching Authority; dated Oct. 24, 2019. [cited by applicant]