IP Library › Granted Patent US 12,396,838
Granted Patent B2
US 12,396,838 · App. 18/421,621 · Granted Aug 26, 2025

Methods of transmitting neural activity

Inventors: Nicholas Lachlan Opie (Parkville, AU); Thomas James Oxley (New York, NY); Gil Simon Rind (Parkville, AU); Stephen Michael Ronayne (Parkville, AU); Sam Emmanuel John (Parkville, AU)
Assignee: The University of Melbourne
A61F2/06A61B5/24A61B5/283A61B5/291A61B5/4052A61B5/4064A61B5/6862A61F2/90A61N1/0529A61B5/0215A61B5/4836A61B5/7207A61B2505/09A61F2/88A61F2230/0067A61F2250/0001
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Quick Facts
Patent No.
US 12,396,838
App. No.
18/421,621
Granted
Aug 26, 2025
Kind
B2
Abstract

Devices, methods and systems for transmitting signals through a device located in a blood vessel of an animal, for stimulating and/or sensing activity of media proximal to the device, wherein the media includes tissue and/or fluid.

Claims (30)

1. A method of transmitting neural activity of a patient, the method comprising:

receiving a signal representative of neural activity from a support structure that maintains, carries, supports or incorporates one or more electrodes and is configured for navigation through a vessel into a brain of the patient, where the support structure comprises a first strut having a first conductive path and a second strut having a second conductive path, where the first conductive path is embedded in the first strut, where the second conductive path is embedded in the first strut and in the second strut, where the first conductive path and the second conductive path extend between a first end and a second end of the first strut, and where the first conductive path and the second conductive path are independent data channels, the method further comprising transmitting or receiving first data via the first conductive path and transmitting or receiving second data different from the first data via the second conductive path;

generating data representing the neural activity using the signal;

transmitting said data to a control unit;

generating a control signal from the control unit; and

transmitting the control signal to an apparatus coupled to the patient.

2. The method of claim 1 , where the one or more electrodes are arranged around a circumference of the support structure, where the support structure has a contracted configuration and an expanded configuration, where when the support structure is in the contracted configuration, the first conductive path and the second conductive path are separated by a first distance, where when the support structure is in the expanded configuration, the first conductive path and the second conductive path are separated by a second distance, and where the second distance is greater than the first distance.

3. The method of claim 1 , where the first strut has a first embedded electrode where the first conductive path is exposed, and where the second strut has a second embedded electrode where the second conductive path is exposed.

4. The method of claim 3 , where the first embedded electrode is located where the first strut intersects the second strut.

5. The method of claim 1 , where the support structure is positioned in the vessel selected from either a vessel in a superior sagittal sinus or a branching cortical vein.

6. The method of claim 1 , where the support structure is positioned in the vessel located adjacent to a visual cortex of a patient.

7. The method of claim 1 , wherein the vessel is located in a muscle for direct muscular stimulation or recording.

8. The method of claim 1 , wherein the vessel adjacent to a peripheral nerve for stimulation or recording.

9. The method of claim 1 , wherein the vessel is adjacent to a sympathetic or parasympathetic nerve.

10. The method of claim 1 , where the signal travels from a first electrode through the first conductive path and through a lead coupled to the first conductive path to the control unit.

11. The method of claim 1 , where at least one of the first strut or second strut has three embedded conductive paths.

12. A method of transmitting neural activity of a patient using a transvascular system, the method comprising:

receiving a signal representative of neural activity from a support structure of the transvascular system, wherein the support structure maintains, carries, supports or incorporates one or more electrodes and is configured for navigation through a vessel into a brain of the patient, where the support structure comprises a first strut having a first conductive path and a second strut having a second conductive path, where the first conductive path is embedded in the first strut, where the second conductive path is embedded in the first strut and in the second strut, where the first conductive path and the second conductive path extend between a first end and a second end of the first strut, and where the first conductive path and the second conductive path are independent data channels, the method further comprising transmitting or receiving first data via the first conductive path and transmitting or receiving second data different from the first data via the second conductive path;

generating data representing the neural activity using the signal;

transmitting said data to a control unit;

generating a control signal from the control unit; and

transmitting the control signal to an apparatus coupled to the patient.

13. The method of claim 12 , where the one or more electrodes are arranged around a circumference of the support structure, where the support structure has a contracted configuration and an expanded configuration, where when the support structure is in the contracted configuration, the first conductive path and the second conductive path are separated by a first distance, where when the support structure is in the expanded configuration, the first conductive path and the second conductive path are separated by a second distance, and where the second distance is greater than the first distance.

14. The method of claim 12 , where the first strut has a first embedded electrode where the first conductive path is exposed, and where the second strut has a second embedded electrode where the second conductive path is exposed.

15. The method of claim 14 , where the first embedded electrode is located where the first strut intersects the second strut.

16. The method of claim 12 , where the support structure is positioned in a vessel selected from either a vessel in a superior sagittal sinus or a branching cortical vein.

17. The method of claim 12 , wherein the vessel is located in a muscle for direct muscular stimulation or recording.

18. The method of claim 12 , wherein the vessel adjacent to a peripheral nerve for stimulation or recording.

19. The method of claim 12 , wherein the vessel is adjacent to a sympathetic or parasympathetic nerve.

20. The method of claim 12 , wherein the transvascular system comprises a coil that extends through a wall in the vessel.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 24, 2024
From: OPIE, NICHOLAS LACHLAN; OXLEY, THOMAS JAMES; RIND, GIL SIMON; RONAYNE, STEPHEN MICHAEL; JOHN, SAM EMMANUEL
To: THE UNIVERSITY OF MELBOURNE
Reel/Frame 066368/0080 →
Priority Claims (2)
AU 2015904302 · Oct 20, 2015 · national
AU 2015905045 · Dec 4, 2015 · national
Continuity (7)
Continuation 18528484 · Dec 4, 2023
Continuation 16943883 · Jul 30, 2020
Continuation 15955412 · Apr 17, 2018
Continuation In Part PCTUS2016057768 · Oct 19, 2016
Provisional Application 62486851 · Apr 18, 2017
Provisional Application 62379625 · Aug 25, 2016
Related Publication 20240207034A1 · Jun 27, 2024
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