IP Library Granted Patent US 12,564,365
Granted Patent B2
US 12,564,365 · App. 18/469,775 · Granted Mar 3, 2026

System and method for generating and displaying tomosynthesis image slabs

Inventors: Nikolaos Gkanatsios (Newtown, CT); Haili Chui (Fremont, CA); Xiangwei Zhang (Fremont, CA)
Assignee: Hologic, Inc.
A61B6/502A61B6/025A61B6/5223G06T11/008G06T11/60G06T2207/10081G06T2207/20021G06T2207/20076G06T2207/30068G06T2210/41
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Quick Facts
Patent No.
US 12,564,365
App. No.
18/469,775
Granted
Mar 3, 2026
Kind
B2
Abstract

A system for processing breast tissue images includes an image processing computer and a user interface operatively coupled to the image processing computer, wherein the image processing computer is configured to obtain image data of breast tissue, processing the image data to generate a set of reconstructed image slices, the reconstructed image slices collectively depicting the breast tissue, process respective subsets of the reconstructed image slices to generate a set of image slabs, each image slab comprising a synthesized 2D image of a portion of the breast tissue obtained from a respective subset of the set of reconstructed image slices.

Claims (38)

1 . A system for processing and storage of breast tissue image data, comprising:

an image viewing device configured to:

retrieve image data of breast tissue from a storage, wherein the image data is stored as a set of one or more image slabs, the set of image slabs collectively depicting the breast tissue and produced by an image processing computer by:

processing the image data to generate a set of reconstructed image slices, the reconstructed image slices collectively depicting the breast tissue;

merging relevant image data from one or more image slices of the set of reconstructed image slices into an image slab that includes the relevant image data, the image slab comprising a constructed 2D image of a portion of the breast tissue; and

storing the image data as the set of one or more image slabs.

2 . The system of claim 1 , wherein the image viewing device is a separate device from the image processing computer.

3 . The system of claim 1 , wherein the image processing computer is further configured to present the one or more image slabs to a user for review prior to storing the one or more image slabs.

4 . The system of claim 3 , wherein storing the image data as the one or more slabs includes manual input received from the user.

5 . The system of claim 4 , wherein the manual input defines one or more of a stack size associated with the one or more image slabs, a number of reconstructed image slices per image slab, and an amount of overlap between adjacent slabs of the one or more slabs.

6 . The system of claim 4 , wherein the manual input defines a target slice around which the image slab should be generated and, in response, the image processing computer is configured to generate a new image slab centered on the target slice.

7 . The system of claim 1 , wherein the set of reconstructed image slices is not stored.

8 . The system of claim 7 , wherein the set of reconstructed image slices is discarded.

9 . The system of claim 1 , wherein each image slab of the set of image slabs is constructed from a predetermined number of image slices of the set of reconstructed image slices with a predetermined amount of overlap between adjacent slabs of the set of image slabs.

10 . The system of claim 9 , wherein one or more of the predetermined number of image slices and the predetermined amount of overlap are determined by user input.

11 . The system of claim 1 , wherein the image processing computer is further configured to determine the relevant image data by:

determining one or more objects or regions of interest to be enhanced in a subset of the set of reconstructed image slices; and

weighing each image of the subset of the set of reconstructed image slices on one of a pixel-by-pixel basis and a region-by-region basis to enhance the one or more objects or regions of interest.

12 . The system of claim 11 , wherein the image slab is constructed by incorporating regions of image slices of the set of reconstructed image slices based on a weight of individual objects of the regions.

13 . The system of claim 12 , wherein the weight of individual objects of the regions is adjusted based on a number of image slices incorporated into the image slab.

14 . The system of claim 11 , wherein determining the one or more objects or regions of interest to be enhanced comprises applying a CAD algorithm to image slices of the set of reconstructed image slices.

15 . The system of claim 1 , further comprising generating an index map associated with the image slab, the index map identifying a source image for the relevant image data.

16 . A method for processing and storage of breast tissue image data, comprising:

receiving image data of breast tissue;

processing the image data to generate a set of reconstructed image slices, the reconstructed image slices collectively depicting the breast tissue;

merging relevant image data from one or more image slices of the set of reconstructed image slices into an image slab that includes the relevant image data, the image slab comprising a constructed 2D image of a portion of the breast tissue; and

storing the image data as a set of image slabs for subsequent viewing, the set of image slabs collectively depicting the breast tissue.

17 . The method of claim 16 , wherein the one or more image slabs comprise a set of image slabs, the set of image slabs collectively depicting the breast tissue.

18 . The method of claim 17 , wherein each image slab of the set of image slabs is constructed from a predetermined number of image slices of the set of reconstructed image slices with a predetermined amount of overlap between adjacent slabs of the set of image slabs.

19 . The method of claim 16 , further comprising determining the relevant image data by:

determining one or more objects or regions of interest to be enhanced in a subset of the set of reconstructed image slices; and

weighing each image of the subset of the set of reconstructed image slices on one of a pixel-by-pixel basis and a region-by-region basis to enhance the one or more objects or regions of interest.

20 . A system for processing breast tissue image data for storage, comprising:

an image processing computer configured to:

receive image data of breast tissue;

process the image data to generate a set of reconstructed image slices, the reconstructed image slices collectively depicting the breast tissue;

merge relevant image data from one or more image slices of the set of reconstructed image slices into an image slab that includes the relevant image data, the image slab comprising a constructed 2D image of a portion of the breast tissue; and

store the image data as a set of image slabs for subsequent viewing, the set of image slabs collectively depicting the breast tissue.

Assignments (4)
RELEASE OF SECURITY INTEREST RECORDED AT REEL/FRAME 065286/0407 Recorded Apr 24, 2026
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: HOLOGIC, INC.; GEN-PROBE INCORPORATED; FAXITRON BIOPTICS, LLC; BIOTHERANOSTICS, INC.; GEN-PROBE PRODESSE, INC.
Reel/Frame 075457/0767 →
SECURITY INTEREST Recorded Apr 8, 2026
From: BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; CYTYC CORPORATION; SUROS SURGICAL SYSTEMS, INC.; GYNESONICS, INC.; BOLDER SURGICAL, LLC; FAXITRON BIOPTICS, LLC; HEALTH BEACONS, INC.; HOLOGIC, INC.
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 075462/0440 →
SECURITY INTEREST Recorded Oct 19, 2023
From: HOLOGIC, INC.; FAXITRON BIOPTICS, LLC; BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 065286/0407 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 19, 2023
From: GKANATSIOS, NIKOLAOS; CHUI, HAILI; ZHANG, XIANGWEI
To: HOLOGIC, INC.
Reel/Frame 064951/0153 →
Continuity (6)
Continuation 17869408 · Jul 20, 2022
Continuation 16792127 · Feb 14, 2020
Continuation 16143181 · Sep 26, 2018
Continuation 15120911
Provisional Application 61946417 · Feb 28, 2014
Related Publication 20240138792A1 · May 2, 2024
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