Granted Patent
B2
US 12,364,532 · App. 18/470,593 · Granted Jul 22, 2025
Methods and devices to treat nasal airways
Assignee:
Aerin Medical Inc.
A61B18/12A61B18/14A61B18/1485A61N1/40A61B5/01A61B2017/248A61B17/2816A61B17/320068A61B2017/320069A61B2017/32007A61B2018/00005A61B2018/00023A61B2018/0016A61B2018/00178A61B2018/0022A61B2018/00327A61B2018/00577A61B2018/00595A61B2018/00642A61B2018/00702A61B2018/00708A61B2018/00791A61B2018/00821A61B2018/00875A61B2018/00886A61B2018/0091A61B2018/00922A61B2018/00982A61B2018/00994A61B18/02A61B2018/0212A61B2018/0225A61B2018/0262A61B18/06A61B18/085A61B18/1206A61B2018/1253A61B2018/126A61B2018/1425A61B2018/143A61B18/1442A61B18/1445A61B18/1477A61B18/16A61B18/18A61B2018/1807A61B18/1815A61B2018/1861A61B18/20A61F5/08A61F5/56A61F7/10A61N1/403A61N5/025A61N5/0603A61N5/0625A61N7/022F04C2270/041
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Abstract
Methods and devices for treating nasal airways are provided. Such devices and methods may improve airflow through an internal and/or external nasal valve, and comprise the use of mechanical re-shaping, energy application and other treatments to modify the shape, structure, and/or air flow characteristics of an internal nasal valve, an external nasal valve or other nasal airways.
Claims (27)
1. A method of reshaping a nasal airway of a nose, the method comprising:
temporarily reshaping a portion of the nasal airway;
inserting multiple radiofrequency needle electrodes of a treatment element through an external skin surface of the nose into nasal tissue adjacent the portion of the nasal airway; and
applying radiofrequency energy to the nasal tissue by activating the multiple radiofrequency needle electrodes,
wherein the portion of the nasal airway remains at least partially reshaped after the radiofrequency energy is applied and the portion of the nasal airway is healed.
2. The method of claim 1 , wherein temporarily reshaping the portion of the nasal airway comprises applying mechanical pressure to a nasal wall from inside a nostril with a reshaping element comprising a convex surface.
3. The method of claim 1 , wherein a portion of each of the multiple radiofrequency needle electrodes is coated with an insulating material.
4. The method of claim 1 , wherein the multiple radiofrequency needle electrodes comprise an array of electrodes disposed along a surface of the treatment element.
5. The method of claim 1 , wherein the multiple radiofrequency needle electrodes comprise bipolar electrodes.
6. The method of claim 1 , wherein the multiple radiofrequency needle electrodes comprise monopolar electrodes.
7. The method of claim 1 , wherein applying the radiofrequency energy comprises applying the radiofrequency energy for a time period of between 15 seconds and 1 minute.
8. The method of claim 1 , wherein applying the radiofrequency energy comprises:
using at least one of the multiple radiofrequency needle electrodes as an active electrode; and
using a remainder of the multiple radiofrequency needle electrodes as return electrodes.
9. The method of claim 8 , further comprising switching which of the multiple radiofrequency needle electrodes is used as the active electrode.
10. The method of claim 1 , wherein applying the radiofrequency energy comprises:
using at least one of the multiple radiofrequency needle electrodes as an active electrode; and
using a surface electrode applied to the external skin surface as a return electrode.
11. The method of claim 1 , wherein applying the radiofrequency energy comprises applying the radiofrequency energy in multiple zones, wherein each of the multiple zones corresponds to one of the multiple radiofrequency needle electrodes, and wherein each of the multiple zones is smaller than a distance between adjacent ones of the multiple radiofrequency needle electrodes.
12. The method of claim 1 , further comprising:
measuring at least one parameter during application of the radiofrequency energy, the at least one parameter being selected from the group consisting of radiofrequency current, radiofrequency voltage, radiofrequency power, and tissue impedance; and
adjusting an amount of radiofrequency energy applied to the nasal tissue, at least in part based on the at least one parameter.
13. The method of claim 1 , further comprising cooling at least one of nasal mucosa or the external skin surface while applying the radiofrequency energy.
14. The method of claim 1 , wherein applying the radiofrequency energy heats the nasal tissue to a temperature in a range from 50 degrees Celsius to 70 degrees Celsius.
15. The method of claim 1 , further comprising:
measuring a temperature of at least one of the external skin surface or nasal mucosa while applying the radiofrequency energy; and
adjusting an amount of the radiofrequency energy applied, at least in part due to the temperature.
Assignments (2)
SECURITY INTEREST
Recorded Dec 20, 2024
From: AERIN MEDICAL INC.
To: ARES CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT AND COLLATERAL AGENT
Reel/Frame 069746/0508 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Sep 20, 2023
From: WOLF, SCOTT J.; FRAZIER, ANDREW
To: AERIN MEDICAL INC.
Reel/Frame 064966/0975 →
Continuity (11)
Provisional Application
61603864
· Feb 27, 2012
Provisional Application
61496930
· Jun 14, 2011
References Cited (400)
US 874178A
· DeForest
· 1907
[cited by applicant]
US 3117571A
· Fry et al.
· 1964
[cited by applicant]
US 3538919A
· Meyer
· 1970
[cited by applicant]
US 3941121A
· Olinger et al.
· 1976
[cited by applicant]
US 4074718A
· Morrison
· 1978
[cited by applicant]
US 4271848A
· Turner et al.
· 1981
[cited by applicant]
US 4411266A
· Cosman
· 1983
[cited by applicant]
US 4887605A
· Angelsen et al.
· 1989
[cited by applicant]
US 5255679A
· Imran
· 1993
[cited by applicant]
US 5348008A
· Bornn et al.
· 1994
[cited by applicant]
US 5505730A
· Edwards
· 1996
[cited by applicant]
US 5507725A
· Savage et al.
· 1996
[cited by applicant]
US 5514131A
· Edwards et al.
· 1996
[cited by applicant]
US 5533499A
· Johnson
· 1996
[cited by applicant]
US 5542916A
· Hirsch et al.
· 1996
[cited by applicant]
US 5562720A
· Stern et al.
· 1996
[cited by applicant]
US 5575788A
· Baker et al.
· 1996
[cited by applicant]
US 5611798A
· Eggers
· 1997
[cited by applicant]
US 5624439A
· Edwards et al.
· 1997
[cited by applicant]
US 5674191A
· Edwards et al.
· 1997
[cited by applicant]
US 5697536A
· Eggers et al.
· 1997
[cited by applicant]
US 5707349A
· Edwards
· 1998
[cited by applicant]
US 5718702A
· Edwards
· 1998
[cited by applicant]
US 5728094A
· Edwards
· 1998
[cited by applicant]
US 5730719A
· Edwards
· 1998
[cited by applicant]
US 5733280A
· Avitall
· 1998
[cited by applicant]
US 5738114A
· Edwards
· 1998
[cited by applicant]
US 5743870A
· Edwards
· 1998
[cited by applicant]
US 5743904A
· Edwards
· 1998
[cited by applicant]
US 5746224A
· Edwards
· 1998
[cited by applicant]
US 5766153A
· Eggers et al.
· 1998
[cited by applicant]
US 5766605A
· Sanders et al.
· 1998
[cited by applicant]
US 5800429A
· Edwards
· 1998
[cited by applicant]
US 5807306A
· Shapland et al.
· 1998
[cited by applicant]
US 5816095A
· Nordell et al.
· 1998
[cited by applicant]
US 5817049A
· Edwards
· 1998
[cited by applicant]
US 5820580A
· Edwards et al.
· 1998
[cited by applicant]
US 5823197A
· Edwards
· 1998
[cited by examiner]
US 5827277A
· Edwards
· 1998
[cited by applicant]
US 5843021A
· Edwards et al.
· 1998
[cited by applicant]
US 5843077A
· Edwards
· 1998
[cited by applicant]
US 5846235A
· Pasricha et al.
· 1998
[cited by applicant]
US 5879349A
· Edwards
· 1999
[cited by applicant]
US 5891134A
· Goble et al.
· 1999
[cited by applicant]
US 5938659A
· Tu et al.
· 1999
[cited by applicant]
US 5944715A
· Goble
· 1999
[cited by applicant]
US 6033397A
· Laufer et al.
· 2000
[cited by applicant]
US 6045549A
· Smethers et al.
· 2000
[cited by applicant]
US 6096033A
· Tu et al.
· 2000
[cited by applicant]
US 6102907A
· Smethers et al.
· 2000
[cited by applicant]
US 6106520A
· Laufer et al.
· 2000
[cited by applicant]
US 6109268A
· Thapliyal et al.
· 2000
[cited by applicant]
US 6126657A
· Edwards et al.
· 2000
[cited by applicant]
US 6131579A
· Thorson et al.
· 2000
[cited by applicant]
US 6139545A
· Utley et al.
· 2000
[cited by applicant]
US 6139546A
· Koenig et al.
· 2000
[cited by applicant]
US 6152143A
· Edwards
· 2000
[cited by applicant]
US 6165173A
· Kamdar et al.
· 2000
[cited by applicant]
US 6179803B1
· Edwards et al.
· 2001
[cited by applicant]
US 6210355B1
· Edwards et al.
· 2001
[cited by applicant]
US 6228079B1
· Koenig
· 2001
[cited by applicant]
US 6231569B1
· Bek et al.
· 2001
[cited by applicant]
US 6238394B1
· Garito et al.
· 2001
[cited by applicant]
US 6273886B1
· Edwards et al.
· 2001
[cited by applicant]
US 6273907B1
· Laufer
· 2001
[cited by applicant]
US 6293941B1
· Strul et al.
· 2001
[cited by applicant]
US 6309386B1
· Bek
· 2001
[cited by applicant]
US 6371926B1
· Thorson et al.
· 2002
[cited by applicant]
US 6383181B1
· Johnston et al.
· 2002
[cited by applicant]
US 6391028B1
· Fanton et al.
· 2002
[cited by applicant]
US 6405732B1
· Edwards et al.
· 2002
[cited by applicant]
US 6416491B1
· Edwards et al.
· 2002
[cited by applicant]
US 6416505B1
· Fleishman et al.
· 2002
[cited by applicant]
US 6425151B2
· Barnett
· 2002
[cited by applicant]
US 6431174B1
· Knudson et al.
· 2002
[cited by applicant]
US 6451013B1
· Bays et al.
· 2002
[cited by applicant]
US 6502574B2
· Stevens et al.
· 2003
[cited by applicant]
US 6517534B1
· McGovern et al.
· 2003
[cited by applicant]
US 6517535B2
· Edwards
· 2003
[cited by applicant]
US 6530924B1
· Ellman et al.
· 2003
[cited by applicant]
US 6551310B1
· Ganz et al.
· 2003
[cited by applicant]
US 6562036B1
· Ellman et al.
· 2003
[cited by applicant]
US 6575969B1
· Rittman et al.
· 2003
[cited by applicant]
US 6589235B2
· Wong et al.
· 2003
[cited by applicant]
US 6640120B1
· Swanson et al.
· 2003
[cited by applicant]
US 6658279B2
· Swanson et al.
· 2003
[cited by applicant]
US 6659106B1
· Hovda et al.
· 2003
[cited by applicant]
US 6669689B2
· Lehmann et al.
· 2003
[cited by applicant]
US 6685648B2
· Flaherty et al.
· 2004
[cited by applicant]
US 6896674B1
· Woloszko et al.
· 2005
[cited by applicant]
US 6911027B1
· Edwards et al.
· 2005
[cited by applicant]
US 6978781B1
· Jordan
· 2005
[cited by applicant]
US 7055523B1
· Brown
· 2006
[cited by applicant]
US 7097641B1
· Arless et al.
· 2006
[cited by applicant]
US 7114495B2
· Lockwood, Jr.
· 2006
[cited by applicant]
US 7322993B2
· Metzger et al.
· 2008
[cited by applicant]
US 7361168B2
· Makower et al.
· 2008
[cited by applicant]
US 7416550B2
· Protsenko et al.
· 2008
[cited by applicant]
US 7442191B2
· Hovda et al.
· 2008
[cited by applicant]
US 7572251B1
· Davison et al.
· 2009
[cited by applicant]
US 7628789B2
· Soltesz et al.
· 2009
[cited by applicant]
US 7655243B2
· Deem et al.
· 2010
[cited by applicant]
US 7678069B1
· Baker et al.
· 2010
[cited by applicant]
US 7780730B2
· Saidi
· 2010
[cited by applicant]
US 7824394B2
· Manstein
· 2010
[cited by applicant]
US 7850683B2
· Elkins et al.
· 2010
[cited by applicant]
US 7997278B2
· Utley et al.
· 2011
[cited by applicant]
US 8088122B2
· Li et al.
· 2012
[cited by applicant]
US 8114062B2
· Muni et al.
· 2012
[cited by applicant]
US 8128617B2
· Bencini et al.
· 2012
[cited by applicant]
US 8137345B2
· McNall, III et al.
· 2012
[cited by applicant]
US 8317781B2
· Owens et al.
· 2012
[cited by applicant]
US 8317782B1
· Ellman et al.
· 2012
[cited by applicant]
US 8718786B2
· Shalev
· 2014
[cited by applicant]
US 8936594B2
· Wolf et al.
· 2015
[cited by applicant]
US 8939970B2
· Stone et al.
· 2015
[cited by applicant]
US 8979841B2
· Kunis et al.
· 2015
[cited by applicant]
US 8986301B2
· Wolf et al.
· 2015
[cited by applicant]
US 9027597B2
· Kubo
· 2015
[cited by applicant]
US 9072597B2
· Wolf et al.
· 2015
[cited by applicant]
US 9125677B2
· Sobol et al.
· 2015
[cited by applicant]
US 9179964B2
· Wolf et al.
· 2015
[cited by applicant]
US 9179967B2
· Wolf et al.
· 2015
[cited by applicant]
US 9237924B2
· Wolf et al.
· 2016
[cited by applicant]
US 9247989B2
· Truckai
· 2016
[cited by applicant]
US 9415194B2
· Wolf et al.
· 2016
[cited by applicant]
US 9433463B2
· Wolf et al.
· 2016
[cited by applicant]
US 9452010B2
· Wolf et al.
· 2016
[cited by applicant]
US 9452087B2
· Holm et al.
· 2016
[cited by applicant]
US 9486278B2
· Wolf et al.
· 2016
[cited by applicant]
US 9498241B2
· Leonhard et al.
· 2016
[cited by applicant]
US 9526571B2
· Wolf et al.
· 2016
[cited by applicant]
US D782657S
· Williams
· 2017
[cited by applicant]
US 9687288B2
· Saadat
· 2017
[cited by examiner]
US 9687296B2
· Wolf et al.
· 2017
[cited by applicant]
US 9763723B2
· Saadat
· 2017
[cited by applicant]
US 9763743B2
· Lin et al.
· 2017
[cited by applicant]
US 9770293B2
· Dresher
· 2017
[cited by applicant]
US 9788886B2
· Wolf et al.
· 2017
[cited by applicant]
US 9801752B2
· Wolf et al.
· 2017
[cited by applicant]
US 9888957B2
· Wolf et al.
· 2018
[cited by applicant]
US 9913682B2
· Wolf et al.
· 2018
[cited by applicant]
US 9943361B2
· Wolf et al.
· 2018
[cited by applicant]
US D860315S
· Chen
· 2019
[cited by applicant]
US D880694S
· Ng et al.
· 2020
[cited by applicant]
US D881904S
· Angeles et al.
· 2020
[cited by applicant]
US D897185S
· Perkins, Jr. et al.
· 2020
[cited by applicant]
US D897186S
· Perkins, Jr. et al.
· 2020
[cited by applicant]
US D904698S
· Moeller et al.
· 2020
[cited by applicant]
US D904852S
· Levand et al.
· 2020
[cited by applicant]
US D906782S
· Brinson et al.
· 2021
[cited by applicant]
US D910408S
· Lin
· 2021
[cited by applicant]
US D911140S
· Hyma et al.
· 2021
[cited by applicant]
US D911141S
· Panosian et al.
· 2021
[cited by applicant]
US D927687S
· Stoklund et al.
· 2021
[cited by applicant]
US 20020010460A1
· Joye et al.
· 2002
[cited by applicant]
US 20020016588A1
· Wong et al.
· 2002
[cited by applicant]
US 20020035361A1
· Houser
· 2002
[cited by applicant]
US 20020049464A1
· Donofrio et al.
· 2002
[cited by applicant]
US 20020087155A1
· Underwood et al.
· 2002
[cited by applicant]
US 20020120259A1
· Lettice et al.
· 2002
[cited by applicant]
US 20020128641A1
· Underwood et al.
· 2002
[cited by applicant]
US 20030069620A1
· Li
· 2003
[cited by applicant]
US 20030144659A1
· Edwards
· 2003
[cited by applicant]
US 20030208194A1
· Hovda et al.
· 2003
[cited by applicant]
US 20030208250A1
· Edwards et al.
· 2003
[cited by applicant]
US 20030225403A1
· Woloszko et al.
· 2003
[cited by applicant]
US 20040030334A1
· Quick et al.
· 2004
[cited by applicant]
US 20040049180A1
· Sharps
· 2004
[cited by applicant]
US 20040193238A1
· Mosher et al.
· 2004
[cited by applicant]
US 20040215235A1
· Jackson et al.
· 2004
[cited by applicant]
US 20040220644A1
· Shalev et al.
· 2004
[cited by applicant]
US 20040230188A1
· Cioanta et al.
· 2004
[cited by applicant]
US 20050020901A1
· Belson et al.
· 2005
[cited by applicant]
US 20050119643A1
· Sobol et al.
· 2005
[cited by applicant]
US 20050171522A1
· Christopherson
· 2005
[cited by applicant]
US 20050171574A1
· Rubinsky et al.
· 2005
[cited by applicant]
US 20050222565A1
· Manstein
· 2005
[cited by applicant]
US 20050234439A1
· Underwood
· 2005
[cited by applicant]
US 20050234443A1
· Rioux et al.
· 2005
[cited by applicant]
US 20050240147A1
· Makower et al.
· 2005
[cited by applicant]
US 20050288665A1
· Woloszko
· 2005
[cited by applicant]
US 20060004323A1
· Chang et al.
· 2006
[cited by applicant]
US 20060009758A1
· Edwards et al.
· 2006
[cited by applicant]
US 20060064086A1
· Odom
· 2006
[cited by applicant]
US 20060095066A1
· Chang et al.
· 2006
[cited by applicant]
US 20060190022A1
· Beyar et al.
· 2006
[cited by applicant]
US 20060195169A1
· Gross et al.
· 2006
[cited by applicant]
US 20060235377A1
· Earley et al.
· 2006
[cited by applicant]
US 20060253117A1
· Hovda et al.
· 2006
[cited by applicant]
US 20060265031A1
· Skwarek et al.
· 2006
[cited by applicant]
US 20060276817A1
· Vassallo et al.
· 2006
[cited by applicant]
US 20070043350A1
· Soltesz et al.
· 2007
[cited by applicant]
US 20070049999A1
· Esch et al.
· 2007
[cited by applicant]
US 20070073282A1
· McGarrigan et al.
· 2007
[cited by applicant]
US 20070179495A1
· Mitchell et al.
· 2007
[cited by applicant]
US 20070219600A1
· Gertner et al.
· 2007
[cited by applicant]
US 20070244529A1
· Choi et al.
· 2007
[cited by applicant]
US 20070287994A1
· Patel
· 2007
[cited by applicant]
US 20080000477A1
· Huster et al.
· 2008
[cited by applicant]
US 20080004613A1
· Barbut et al.
· 2008
[cited by applicant]
US 20080021369A1
· Deem et al.
· 2008
[cited by applicant]
US 20080027423A1
· Choi et al.
· 2008
[cited by applicant]
US 20080027480A1
· van der Burg et al.
· 2008
[cited by applicant]
US 20080027520A1
· Choi et al.
· 2008
[cited by applicant]
US 20080082090A1
· Manstein
· 2008
[cited by applicant]
US 20080154237A1
· Chang et al.
· 2008
[cited by applicant]
US 20080154343A1
· Li et al.
· 2008
[cited by applicant]
US 20080312644A1
· Fourkas et al.
· 2008
[cited by applicant]
US 20090018485A1
· Krespi et al.
· 2009
[cited by applicant]
US 20090124958A1
· Li et al.
· 2009
[cited by applicant]
US 20090143821A1
· Stupak
· 2009
[cited by applicant]
US 20090163890A1
· Clifford et al.
· 2009
[cited by applicant]
US 20090192505A1
· Askew et al.
· 2009
[cited by applicant]
US 20090292358A1
· Saidi
· 2009
[cited by applicant]
US 20090299355A1
· Bencini et al.
· 2009
[cited by applicant]
US 20100144996A1
· Kennedy et al.
· 2010
[cited by applicant]
US 20100152730A1
· Makower et al.
· 2010
[cited by applicant]
US 20100160906A1
· Jarrard
· 2010
[cited by applicant]
US 20100174283A1
· McNall, III et al.
· 2010
[cited by applicant]
US 20100204560A1
· Salahieh et al.
· 2010
[cited by applicant]
US 20110009737A1
· Manstein
· 2011
[cited by applicant]
US 20110125149A1
· El-Galley et al.
· 2011
[cited by applicant]
US 20110180064A1
· Tanaka et al.
· 2011
[cited by applicant]
US 20110282268A1
· Baker et al.
· 2011
[cited by applicant]
US 20110301587A1
· Deem et al.
· 2011
[cited by applicant]
US 20120029512A1
· Willard et al.
· 2012
[cited by applicant]
US 20120039954A1
· Cupit et al.
· 2012
[cited by applicant]
US 20120123411A1
· Ibrahim et al.
· 2012
[cited by applicant]
US 20120179154A1
· Goldberg et al.
· 2012
[cited by applicant]
US 20120316557A1
· Sartor et al.
· 2012
[cited by applicant]
US 20130218158A1
· Danek et al.
· 2013
[cited by applicant]
US 20130281997A1
· Davie
· 2013
[cited by applicant]
US 20140114233A1
· Deem et al.
· 2014
[cited by applicant]
US 20150148791A1
· Birdsall et al.
· 2015
[cited by applicant]
US 20170105793A1
· Cao
· 2017
[cited by applicant]
US 20180177542A1
· Wolf et al.
· 2018
[cited by applicant]
US 20180228551A1
· Moe
· 2018
[cited by applicant]
US 20180333195A1
· Greep et al.
· 2018
[cited by applicant]
US 20190076185A1
· Dinger et al.
· 2019
[cited by applicant]
US 20190201069A1
· Wolf et al.
· 2019
[cited by applicant]
US 20200129223A1
· Angeles et al.
· 2020
[cited by applicant]
US 20210169566A1
· Townley
· 2021
[cited by applicant]
US 20220257272A1
· Wolf et al.
· 2022
[cited by applicant]
US 20230062359A1
· Wolf et al.
· 2023
[cited by applicant]
US 20230293222A1
· Wolf et al.
· 2023
[cited by applicant]
US 20240366286A1
· Wolf et al.
· 2024
[cited by applicant]
CN 2225227Y
· 1996
[cited by applicant]
CN 2621723Y
· 2004
[cited by applicant]
CN 101325919
· 2008
[cited by applicant]
CN 103055417A
· 2013
[cited by applicant]
DE 102007006467B3
· 2008
[cited by applicant]
WO 1999007299
· 1999
[cited by applicant]
WO 1999030655A1
· 1999
[cited by applicant]
WO 2001043653
· 2001
[cited by applicant]
WO 2003024349
· 2003
[cited by applicant]
WO 2007037895
· 2007
[cited by applicant]
WO 2007134005
· 2007
[cited by applicant]
WO 2009048580A1
· 2009
[cited by applicant]
WO 2010077980
· 2010
[cited by applicant]
WO 2010077980A1
· 2010
[cited by applicant]
WO 2012174161
· 2012
[cited by applicant]
WO 2013028998
· 2013
[cited by applicant]
WO 2014022436
· 2014
[cited by applicant]
WO 2015047863
· 2015
[cited by applicant]
WO 2015048806
· 2015
[cited by applicant]
WO 2015153696
· 2015
[cited by applicant]
WO 2016183337A2
· 2016
[cited by applicant]
Extended European Search Report for Application No. 19159707.9, mailed Nov. 9, 2019, 7 pages.
[cited by applicant]
Buckley et al., “High-resolution spatial mapping of shear properties in cartilage,” J Biomech., Mar. 3, 2010;43 (4):796-800, Epub Nov. 5, 2009.
[cited by applicant]
Buckley et al., “Mapping the depth dependence of shear properties in articular cartilage,” J Biomech., 41 (11):2430-2437, Epub Jul. 10, 2008.
[cited by applicant]
Chen et al., China Journal of Endoscopy, vol. 11, No. 3. pp. 239-243, Mar. 2005, [English Translation of Title] “Radiofrequency treatment of nasal posterior-under nerve ethmoidal nerve and infraturbinal for perennial al…
[cited by applicant]
Cole, “Biophysics of nasal airflow: a review,” Am J Rhinol., 14(4):245-249, Jul.-Aug. 2000.
[cited by applicant]
Fang et al., J First Mil Med Univ, vol. 25 No. 7, pp. 876-877, 2005, [English translation of title] “Nasal endoscopy combined with multiple radiofrequency for perennial allergic rhinitis” [also translated as] “Nasal End…
[cited by applicant]
Griffin et al., “Effects of enzymatic treatments on the depth-dependent viscoelastic shear properties of articular cartilage,” J Orthop Res., 32(12):1652-1657, Epub Sep. 5, 2014.
[cited by applicant]
International Search Report and Written Opinion for PCT/US2012/042316, mailed Aug. 24, 2012, 15 pages.
[cited by applicant]
International Search Report and Written Opinion for PCT/US2014/054726, mailed Dec. 23, 2014, 5 pages.
[cited by applicant]
International Search Report and Written Opinion for PCT/US2015/023742, mailed Jun. 29, 2015, 5 pages.
[cited by applicant]
Kjaergaard et al., “Relation of nasal air flow to nasal cavity dimensions,” Arch Otolaryngol Head Neck Surg., 135 (6):565-570, Jun. 2009.
[cited by applicant]
Kong et al., Journal of Clinical Otorhinolaryngology, 2005. “Clinical observation on radiofrequency ablation treatment in perennial allergic rhinitis,” Retrieved from the Internet: <URL:http://en.cnki.com.cn/Article_en/…
[cited by applicant]
Liu et al., China Journal of Endoscopy, vol. 14, No. 11, pp. 1127-1130, Nov. 2008, [English Translation of Title]“Impact of treatment of perennial rhinitis by radiofrequency thermo-coagulations to vidian and antirior et…
[cited by applicant]
Silverberg et al., “Structure-function relations and rigidity percolation in the shear properties of articular cartilage,” Biophys J., 107(7):1721-1730, Oct. 7, 2014.
[cited by applicant]
Singapore Search Report for Application Serial No. 201309238-2, mailed Apr. 17, 2014, 27 pages.
[cited by applicant]
Stewart et al., “Development and validation of the Nasal Obstruction Symptom Evaluation (NOSE) scale,” Otolaryngol Head Neck Surg., 130(2):157-163, Feb. 2004.
[cited by applicant]
Stupak, “A Perspective on the Nasal Valve,” Dept. of Otorhinolaryngology, Albert Einstein College of Medicine, Nov. 6, 2009.
[cited by applicant]
Stupak, “Endonasal repositioning of the upper lateral cartilage and the internal nasal valve,” Ann Otol Rhinol Laryngol., 120(2):88-94, Feb. 2011.
[cited by applicant]
Cole, “The four components of the nasal valve,” Am J Rhinol., 17(2):107-110, Mar.-Apr. 2003.
[cited by applicant]
Extended European Search Report for Application No. 23177809.3 mailed Sep. 25, 2023.
[cited by applicant]
Extended European Search Report for Application No. 19199126.4, mailed Dec. 9, 2019, 6 pages.
[cited by applicant]
Extended European Search Report for Application No. 21172995.9 mailed Jul. 9, 2021.
[cited by applicant]
Fang Chao-xin and Zhen Shao-Shao, Nasal endoscopy combined with multiple radiofrequency for perennial allergic rhinitis, 25(07) J. First Mil. Medic Univ. 876 (Jul. 20, 2005).
[cited by applicant]
Liang “Radiofrequency Treatment of Ethmoidal Nerve with Allergic Rhinitis Under Nasal Endoscopy”, J. Clin. Otorhinolaryngol, vol. 13, No. 8, pp. 341-342, Aug. 1999.
[cited by applicant]
Search Report in European Application No. 18204723.3 dated Feb. 18, 2019, 8 pages.
[cited by applicant]
Supplementary European Search Report for U.S. Appl. No. 15/772,528, mailed Sep. 26, 2017, 7 pages.
[cited by applicant]
Arora et al., “Cryodestruction of Vidian Nerve Branches,” Indian J. Otolaryngology, vol. 32, No. 3, Sep. 1980, pp. 80-82.
[cited by applicant]
Back et al., “Submucosal Bipolar Radiofrequency Thermal Ablation of Inferior Turbinates: A Long-Tenn Follow-up with Subjective and Objective Assessment,” Laryngoscope, vol. 112, No. 10, Oct. 2002, pp. 1806-1812.
[cited by applicant]
Banhiran et al., “Quality of life in patients with chronic rhinitis after radiofrequency inferior turbinate reduction,” J. Med Assoc Thai, vol. 93, No. 8, 2010, pp. 950-957.
[cited by applicant]
Bronzino, Medical Devices and Systems, The Biomedical Engineering Handbook (3rd ed. 2006), Chapter 63, Electrosurgical Devices, pp. 63-1-63-9.
[cited by applicant]
Chen et al., “Preliminary study on radiofrequency thermocoagulation of the posterior inferior nerve, anterior ethmoidal nerve, and inferior turbinate under nasal endoscopy for the treatment of perennial allergic rhiniti…
[cited by applicant]
Chen et al., “Radiofrequency treatment of nasal posterior-under nerve, ethmoidal nerve and infraturbinal for perennial allergic rhinitis under nasal endoscope,” China Journal of Endoscopy, vol. 11, No. 3, Mar. 2005, pp.…
[cited by applicant]
Coste et al., “Radiofrequency Is a Safe and Effective Treatment of Turbinate Hypertrophy,” Laryngoscope, vol. 111, No. 5, May 2001, pp. 894-899.
[cited by applicant]
Fang et al., “Nasal Endoscopy Combined with Multiple Radiofrequency for Perennial Allergic Rhinitis,” J. First Mil Med Univ, vol. 25, No. 7, 2005, pp. 876-877 (English Translation); IPR2024-00282, “Translator Declaratio…
[cited by applicant]
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