Granted Patent B2

US 12,193,813 · App. 18/496,255 · Granted Jan 14, 2025

Inventors: Massi Joe E. Kiani (Laguna Niguel, CA); Mathew Paul (Irvine, CA); Jesse Chen (Foothill Ranch, CA); Marcelo M. Lamego (Cupertino, CA)

Assignee: Masimo Corporation

A61B5/14552A61B5/6826A61B5/7207A61B5/721

Abstract

Claims (34)

1. An active-pulse blood analysis system, comprising:

an optical emitter that illuminates a tissue site with multiple wavelengths of optical radiation;

an optical sensor that outputs sensor signals responsive to the optical radiation after attenuation by pulsatile blood flow within the tissue site;

a filter that receives the sensor signals;

one or more memory devices storing an arterial calibration curve and a venous calibration curve; and

one or more processors configured to:

receive, from the filter, filtered sensor data;

generate an arterial ratio and an active-pulse ratio from the filtered sensor data;

select an output saturation value from one of an arterial saturation value (SpO 2 ) as determined from the arterial ratio or a venous oxygen saturation value (SpvO 2 ) as determined from the active-pulse ratio, wherein the selection is based on detected motion; and

display the output saturation value based on the selection.

2. The active-pulse blood analysis system of claim 1 , wherein the arterial calibration curve is numerically-derived by correlating arterial blood draws with corresponding sensor data responsive to pulsatile arterial blood flow.

3. The active-pulse blood analysis system of claim 2 , wherein the arterial calibration curve comprises a lookup table.

4. The active-pulse blood analysis system of claim 1 , wherein the filter comprises a first bandpass filter and a second bandpass filter.

5. The active-pulse blood analysis system of claim 4 , wherein the first bandpass filter has a first passband configured to generate arterial pulse data and the second bandpass filter has a second passband configured to generate active-pulse data.

6. The active-pulse blood analysis system of claim 5 , wherein the first passband is at a lower range of frequencies and the second passband is at a higher range of frequencies.

7. The active-pulse blood analysis system of claim 1 , wherein the one or more processors are further configured to:

determine the arterial saturation value (SpO 2 ) by comparing the generated arterial ratio to the arterial calibration curve; and

determine the venous oxygen saturation value (SpvO 2 ) by comparing the generated active-pulse ratio to the venous calibration curve.

8. An active-pulse blood analysis method comprising:

receiving sensor data responsive to optical radiation after attenuation by pulsatile blood flow within a tissue site from an optical sensor that illuminates the tissue site with multiple wavelengths of optical radiation;

storing via one or more memory devices, an arterial calibration curve and a venous calibration curve;

filtering the sensor data to separate the sensor data into arterial pulse data and active-pulse data;

generating an arterial ratio from the arterial pulse data;

generating an active-pulse ratio from the active-pulse data;

selecting an output saturation value from one of an arterial saturation value (SpO 2 ) as determined from arterial pulse data and a venous oxygen saturation value (SpvO 2 ) as determined from active-pulse data, wherein the selecting is based on detected motion; and

outputting the output saturation based on the selection.

9. The active-pulse blood analysis method of claim 8 , wherein the arterial calibration curve is numerically-derived by correlating arterial blood draws with corresponding sensor data responsive to pulsatile arterial blood flow.

10. The active-pulse blood analysis method of claim 9 , wherein the arterial calibration curve comprises a lookup table.

11. The active-pulse blood analysis method of claim 8 , wherein filtering comprises using a first bandpass filter and a second bandpass filter.

12. The active-pulse blood analysis method of claim 11 , wherein the first bandpass filter has a first passband configured to generate arterial pulse data and the second bandpass filter has a second passband configured to generate active-pulse data.

13. The active-pulse blood analysis method of claim 12 , wherein the first passband is at a lower range of frequencies and the second passband is at a higher range of frequencies.

14. The active-pulse blood analysis method of claim 8 further comprising:

determining the arterial saturation value (SpO 2 ) by comparing the generated arterial ratio to the arterial calibration curve; and

determining the venous oxygen saturation value (SpvO 2 ) by comparing the generated active-pulse ratio to the venous calibration curve.

Assignments (1)

Continuity (8)

References Cited (400)