HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS
Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by dysregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).
1 - 20 . (canceled)
21 . A method of treating acne in a subject in need thereof, the method comprising administering to the subject a fatty acid synthase inhibitor having a formula of:
or a pharmaceutically acceptable salt thereof.
22 . A method of treating acne in a subject in need thereof, the method comprising administering to the subject a fatty acid synthase inhibitor having a formula of: