IP Library Granted Patent US 12,546,842
Granted Patent B2
US 12,546,842 · App. 18/546,411 · Granted Feb 10, 2026

Sensing motion in MRI using RF intermodulation

Inventors: Shimon M. Lustig (Moraga, CA); Suma Mandayam Anand (Berkeley, CA); Alan Dong (San Francisco, CA)
Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
G01R33/56509G01R33/3621
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Quick Facts
Patent No.
US 12,546,842
App. No.
18/546,411
Granted
Feb 10, 2026
Kind
B2
Abstract

A method of sensing motion in an MRI scanner includes transmitting at least two tones having different frequencies, using intermodulation to combine the two tones, transmitting the two tones as a combined signal during an MRI scan of a patient, receiving the combined signal using a receiver in the MRI scanner, demodulating the combined signal to produce a demodulated signal, and analyzing the demodulated signal to detect motion of the patient during the MRI scan.

Claims (30)

1 . A method of sensing motion in an MRI scanner, comprising:

transmitting at least two tones having different frequencies;

mixing the at least two tones using intermodulation to combine the two tones into a combined signal within MRI receiver bandwidth;

transmitting the two tones as the combined signal during an MRI scan of a patient;

receiving the combined signal using a selected receiver coil from one or more existing receiver coils in the MRI scanner;

demodulating the combined signal to produce a demodulated signal; and

analyzing the demodulated signal to detect motion of the patient being scanned during the MRI scan.

2 . The method as claimed in claim 1 , wherein the mixing is passively performed at a preamplifier of the selected receiver coil of the MRI scanner.

3 . The method as claimed in claim 1 , wherein the mixing is performed by a device external to the MRI scanner.

4 . The method as claimed in claim 1 , further comprising digitizing the demodulated signal.

5 . The method as claimed in claim 1 , wherein demodulating the combined signal comprises outputting the magnitude and the phase of the combined signal.

6 . The method as claimed in claim 1 , wherein outputting the phase of the combined signal comprises:

selecting one of the receiver coils as a reference coil; and

subtracting a phase of the reference coil from other of the one or more receiver coils to produce the phase output.

7 . The method as claimed in claim 1 , further comprising amplifying the combined signal prior to transmitting.

8 . The method as claimed in claim 1 , further comprising high-pass filtering the combined signal prior to transmitting.

9 . The method as claimed in claim 1 , wherein transmitting the at least two tones further comprises selecting the at least two tones such that a frequency determined by frequencies of the two tones falls within a receiver bandwidth of the MRI scanner.

10 . The method as claimed in claim 9 , wherein a product of the two tones equals a frequency of a first tone multiplied by a first signed integer added to a frequency of a second tone multiplied by a second signed integer.

11 . The method as claimed in claim 1 , wherein receiving the combined signal comprises receiving the combined signal at one of a set of the selected receiver coil, a software-defined radio, or an external radio receiver.

12 . A motion sensing system for a MRI scanner, comprising:

one or more transmitters to generate at least two different frequency tones;

a mixer to mix the at least two different frequency tones using intermodulation to produce a mixed signal having a frequency within a frequency of a receiver of the MRI scanner;

one or more antennas to transmit the mixed signal into a bore of the MRI scanner occupied by a patient;

a receiver in the MRI scanner to receive the mixed signal; and

one or more processors to execute code to analyze the mixed signal to determine patient motion.

13 . The motion sensing system as claimed in claim 12 , wherein the mixer comprises one of a preamplifier or an RF mixer.

14 . The motion sensing system as claimed in claim 12 , wherein the one or more processors resides in the MRI scanner.

15 . The motion sensing system as claimed in claim 12 , wherein at least one of the one or more processors reside in a computer external to the MRI scanner.

16 . The motion sensing system as claimed in claim 12 , wherein the one or more transmitters comprises one of software-defined radios or pure tone generators.

17 . The motion sensing system as claimed in claim 12 , wherein the receiver comprises one of either receiver coils in the MRI scanner, a software-defined radio, or other radio receiver.

Assignments (2)
CONFIRMATORY LICENSE Recorded Jan 10, 2024
From: UNIVERSITY OF CALIFORNIA BERKELEY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 066255/0316 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 15, 2023
From: LUSTIG, SHIMON M.; ANAND, SUMA MANDAYAM; DONG, ALAN
To: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Reel/Frame 064588/0552 →
Continuity (3)
Provisional Application 63150423 · Feb 17, 2021
Related Publication 20240133988A1 · Apr 25, 2024
Related Publication 20240230813A9 · Jul 11, 2024
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