IP Library › Granted Patent US 12,455,981
Granted Patent B2
US 12,455,981 · App. 18/577,940 · Granted Oct 28, 2025

Personal information protection management system for genomic data

Inventors: Mikio Fujiwara (Tokyo, JP); Masahiro Takeoka (Tokyo, JP); Masahide Sasaki (Tokyo, JP); Masao Nagasaki (Kyoto, JP)
Assignee: National Institute of Information and Communications Technology
G06F21/6245G06F21/602
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,455,981
App. No.
18/577,940
Granted
Oct 28, 2025
Kind
B2
Abstract

A personal information protection management system for genomic data includes data storage, role storage, a filter, and a data output part. The data storage is configured to store genomic data. The role storage is configured to store an identifier of a data output destination and a role in association with each other, the role including a detail of filtering for removing from genomic data a part that is not to be outputted. The filter is configured to filter the stored genomic data based on the stored role. The data output part is configured to output the filtered genomic data to the data output destination. The filter is configured to obtain a data request signal transmitted from the data output destination and, based on the role that is associated with the identifier included in the obtained data request signal, filter the genomic data.

Claims (22)

1. A personal information protection management system for genomic data, comprising:

data storage configured to store genomic data, the data storage including a plurality of server computers that are connected to each other by a quantum cryptographic network;

role storage configured to store an identifier of a data output destination and a role in association with each other, the role including a detail of filtering for removing from the genomic data a part that is not to be outputted; and

a hardware processor configured to:

filter the stored genomic data based on the stored role; and

output the filtered genomic data to the data output destination, wherein

the genomic data is distributed among the plurality of server computers by a secret sharing scheme and stored as shares in the plurality of server computers,

the genomic data is stored in the plurality of server computers in a FASTQ format including a quality score and sequence information, and

the hardware processor is configured to:

obtain a data request signal transmitted from the data output destination and, based on the role that is associated with the identifier included in the obtained data request signal, filter the genomic data;

reconstruct the genomic data from the shares and decrypt the reconstructed genomic data;

convert the decrypted genomic data into a VCF format that includes sequence information of a part where a variation occurs and location information of the variation;

filter the genomic data converted into the VCF format based on the stored role;

perform quantum encryption of the filtered genomic data and generate a quantum key for decrypting the quantum-encrypted genomic data; and

transmit the quantum-encrypted genomic data and the quantum key to the data output destination.

2. The personal information protection management system for genomic data according to claim 1 ,

wherein

the hardware processor is configured to filter the decrypted genomic data based on the stored role.

3. The personal information protection management system for genomic data according to claim 1 , wherein

the data output destination and the hardware processor are configured to communicatively connect to each other using authentication, and

the hardware processor is configured to:

transmit the quantum-encrypted genomic data and the quantum key to the authenticated data output destination.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 10, 2024
From: FUJIWARA, MIKIO; TAKEOKA, MASAHIRO; SASAKI, MASAHIDE; NAGASAKI, MASAO
To: NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY
Reel/Frame 066074/0569 →
Priority Claims (1)
JP 2021-118556 · Jul 19, 2021 · national
Continuity (1)
Related Publication 20240320369A1 · Sep 26, 2024
References Cited (28)
US 10574446B2 · Fu · 2020 [cited by examiner]
US 20030208378A1 · Thangaraj · 2003 [cited by examiner]
US 20150100781A1 · Yann · 2015 [cited by examiner]
US 20170262579A1 · Agrawal et al. · 2017 [cited by applicant]
US 20180373834A1 · Cho · 2018 [cited by examiner]
US 20200234794A1 · Esteves-Veríssimo et al. · 2020 [cited by applicant]
US 20210083864A1 · Bush · 2021 [cited by examiner]
US 20210183468A1 · Hahm et al. · 2021 [cited by applicant]
US 20210210215A1 · Davis-Turak et al. · 2021 [cited by applicant]
US 20210351916A1 · Tsuchida et al. · 2021 [cited by applicant]
US 20210409400A1 · Palanisamy · 2021 [cited by examiner]
US 20220209934A1 · Karimi · 2022 [cited by examiner]
US 20230048167A1 · Gai · 2023 [cited by examiner]
US 20230094541A1 · Gai · 2023 [cited by examiner]
US 20240154884A1 · Jain · 2024 [cited by examiner]
US 20240291640A1 · Amer · 2024 [cited by examiner]
JP 2008011360A · 2008 [cited by applicant]
JP 2018503167A · 2018 [cited by applicant]
WO 2020075273A1 · 2020 [cited by applicant]
Fujiwara et al., “3. Quantum Optical Network Technology, 3-1. Current Status of Quantum Key Distribution Network Research and Development”, Journal of the National Institute of Information and Communications Technology,… [cited by applicant]
Office Action for Japanese Patent Application No. 2021-118556, dated Nov. 27, 2024. [cited by applicant]
Task Force for Promoting the Practical Use of Genomic Information in Medical Treatments, “Regarding the Handling of Genomic Data Under the Revised Personal Information Protection Act (TF summary), Summary Version”, Japa… [cited by applicant]
International Search Report and Written Opinion pertaining to PCT/JP2022/026412, mailed Oct. 4, 2022. [cited by applicant]
Japanese online page of Illumina, Inc., for a product called “Dragen Germline” at [https://jp.illumina.com/products/by-type/informatics-products/basespace-sequence-hub/apps/dragen-germline.html](D1, Non-Patent Literatur… [cited by applicant]
Masahiro Takeoka, “Tokyo QKD Network: Construction and utilization of quantum cryptography network testbed”, Mar. 8, 2021, NICT's Integrated Testbed Symposium 2021, avaliable online at [https://testbed.nict.go.jp/event/… [cited by applicant]
Extended European Search Report pertaining to European Patent Application No. 22845770.1, issued Jun. 27, 2025. [cited by applicant]
Fujiwara et al., “Secure Secondary Utilization System of Genomic Data Using Quantum Secure Cloud”, arxiv.org, Cornell University Library, 2002. [cited by applicant]
Tajima et al., “Quantum Key Distribution Network for Multiple Applications”, Quantum Science and Technology, 2017, 2, 034003. [cited by applicant]