Granted Patent B2

US 12,311,124 · App. 18/589,076 · Granted May 27, 2025

Inventors: Daniel Frank Massimini (Brooklyn Park, MN); Daniel Lee Krautkremer (Plymouth, MN); Haiping Shao (Plymouth, MN); Roger W. McGowan (Otsego, MN)

Assignee: BOSTON SCIENTIFIC SCIMED, INC.

A61M25/0133A61B17/22A61B18/245A61B18/26A61L27/20A61M25/0009A61M25/0155A61M25/09A61B2017/22062A61B2018/0022A61B2018/00285A61B2018/2261A61B2018/2266A61B2018/2277A61B2018/2294A61B2018/263A61B2090/306A61L2400/12A61M2025/09008A61M2025/09183A61M2202/0415A61M2205/3592A61M2205/587

Abstract

Claims (19)

1. A balloon catheter system comprising:

a catheter configured to advance to a treatment site, the catheter comprising an elongate shaft and a balloon that is coupled to the elongate shaft, the catheter defining an inflation fluid pathway including an inflation lumen and an interior of the balloon that are in fluid communication;

a inflation fluid fortification component disposed on a surface of the inflation fluid pathway, the inflation fluid fortification component including at least one of carbon and iron, and being configured to be mixed with a base inflation fluid introduced into the inflation fluid pathway to form a fortified balloon inflation fluid, the fortified balloon inflation fluid configured to reduce a threshold for inducing plasma formation in the fortified balloon inflation fluid compared to the base inflation fluid; and

a first energy guide that is disposed along the elongate shaft and is positioned at least partially within the balloon, the first energy guide being configured to be in communication with an energy source and including an end disposed within the balloon.

2. The catheter system of claim 1 , wherein the inflation fluid fortification component includes an iron dextran.

3. The catheter system of claim 1 , wherein the inflation fluid fortification component includes nanoparticles.

4. The catheter system of claim 1 , wherein the inflation fluid fortification component includes one of iron nanoparticles, gold nanoparticles, copper nanoparticles, carbon nanoparticles, carbon nanotubes, gold-coated carbon nanotubes and copper-coated carbon nanotubes.

5. The catheter system of claim 1 , wherein the base inflation fluid includes saline and contrast medium in a ratio of saline to contrast medium of from 25:75 volume percent to 75:25 volume percent.

6. The catheter system claim 1 , wherein the inflation fluid fortification component is configured to modify one of viscosity, density and surface tension of the fortified balloon inflation fluid compared to the base inflation fluid.

7. A method for generating pressure waves to induce fractures at a treatment site within or adjacent a vessel wall of a blood vessel, the method comprising the steps of:

advancing a catheter to the treatment site within the blood vessel, the catheter comprising an elongate shaft, a balloon coupled to the elongate shaft, and an energy guide disposed along the elongate shaft so that the energy guide is positioned at least partially within the balloon;

expanding the balloon with a fortified balloon inflation fluid, the fortified balloon inflation fluid comprising a base inflation fluid and a fortification component, the fortified balloon inflation fluid being configured to reduce a threshold for inducing plasma formation in the fortified balloon inflation fluid compared to the base inflation fluid, wherein the fortification component includes one of carbon and iron, wherein, expanding the balloon with the fortified balloon inflation fluid includes: providing the fortification component as a coating disposed on an inside surface of a balloon wall or on the elongate shaft in fluid communication with the base inflation fluid, providing the base inflation fluid to the balloon, and the base inflation fluid solvating the fortification component coating to form the fortified balloon inflation fluid; and

activating an energy source in communication with the energy guide and the fortified balloon inflation fluid to provide a pulses of energy from the energy source to the fortified balloon inflation fluid so that plasma formation occurs in the fortified balloon inflation fluid.

8. The method of claim 7 , wherein the fortification component comprises one of iron dextran and nanoparticles.

9. The method of claim 7 , wherein the fortification component comprises nanoparticles, the nanoparticles including one of iron nanoparticles, gold nanoparticles, copper nanoparticles, carbon nanoparticles, carbon nanotubes, gold-coated carbon nanotubes and copper-coated carbon nanotubes.

10. The method of claim 7 , wherein the first energy guide comprises an optical fiber and wherein the energy source comprises a laser.

11. The method of claim 7 , wherein the pulses of energy from the energy source are delivered at a frequency of between 1 Hz and 30 Hz.

12. The method of claim 7 , wherein the pulses of energy from the energy source are delivered at a frequency of between 30 Hz and 5000 Hz.

13. The method of claim 7 , wherein the base inflation fluid comprises saline and contrast medium in a ratio of saline to contrast medium of 25:75 volume percent to 75:25 volume percent.

Assignments (1)

Continuity (6)

References Cited (400)