Expandable medical device and method of use thereof
The present invention relates generally to expandable medical devices including a light-activated shape-memory polymer. In certain embodiments, the devices include, for example, balloon catheters, used to treat narrowed or obstructed portions of a body vessel, and retrieval devices, used to remove obstructions from a body vessel. Certain aspects of the invention relate to methods of manufacturing and using such devices.
1. An implantable medical device comprising:
an elongated catheter extending from a distal end to a proximal end and comprising a first lumen;
a plurality of optical fibers extending in the first lumen from the proximal end to the distal end;
an expandable body attaching to a distal end of the elongated catheter, wherein the expandable body comprises an light-sensitive polymeric material,
wherein a distal end of the plurality of optical fibers is optically coupled to the light-sensitive polymeric material,
wherein the expandable body comprises a hollow tubular body having a tubular wall comprising the light-sensitive polymeric material and defining an internal lumen, and
wherein the tubular wall comprises of plurality of interconnected segments, wherein each segment comprises a node point comprising the light-sensitive polymeric material.
2. The implantable medical device of claim 1 , further comprising a light source optically coupled to a proximal end of the plurality of optical fibers.
3. The implantable medical device of claim 2 , wherein the light source is selected from the group consisting of a laser and a light emitting diode.
4. The implantable medical device of claim 1 , the expandable body having an expanded configuration and a collapsed configuration, wherein the expandable body transitions from the collapsed configuration to the expanded configuration upon optical illumination of the light-sensitive polymeric material.
5. The implantable medical device of claim 1 , wherein the light-sensitive polymeric material comprises a polymer coupled to a material selected from the group consisting of cinnamic acid and cinnamylidene acetic acid.
6. The implantable medical device of claim 1 , where at least one of the interconnected segments has expanded configuration and a collapsed configuration, wherein transition from the collapsed configuration to the expanded configuration comprises lengthening of the segment in a first direction without a change in dimension is a second perpendicular dimension.
7. The implantable medical device of claim 1 , wherein the expandable body is selected from the group consisting of a balloon, a stent, a stent graft and a retrieval device.
8. The implantable medical device of claim 1 , wherein the expandable body is a stent or a balloon.
9. The implantable medical device of claim 1 , wherein the expandable body comprises a plurality of holes, wherein at least one of the plurality of holes increases in size upon expansion of the expandable body.
10. An implantable medical device comprising:
an elongated catheter comprising a first lumen;
a plurality of optical fibers extending from a proximal end to a distal end of the first lumen;
a light source optically coupled to a proximal end of the plurality of optical fibers;
an hollow expandable body having a plurality of holes and attaching to a distal end of the elongated catheter, wherein the expandable body comprises an light-sensitive polymeric material,
wherein a distal end of the plurality of optical fibers is optically coupled to the light-sensitive polymeric material,
wherein there are a plurality of light sources, and
wherein a first portion of the plurality of optical fibers is optically coupled to a first group of the plurality of light sources and to the light-sensitive polymeric material at a first region of the expandable body and wherein a second portion of the optical fibers is optically coupled to a second group of the plurality of light sources and to the light-sensitive polymeric material at a second region of the expandable body.
11. The implantable medical device of claim 10 , further comprising a second lumen extending from a proximal end to a distal end of the elongated catheter.
12. The implantable medical device of claim 10 , wherein the plurality of light sources are selected from the group consisting of a laser and a light emitting diode.
13. The implantable medical device of claim 10 , wherein the implantable medical device comprises a balloon.
14. The implantable medical device kit of claim 10 , wherein the light-sensitive polymeric material comprises a polymer coupled to a material selected from the group consisting of cinnamic acid and cinnamylidene acetic acid.