Cooled mechanical circulatory support system and method of operation
A mechanical circulatory support system for a heart having a cooling element and a method for using the system to treat the effects of a cardiac episode. The support system has a pump comprising a rotor, the rotor having at least one blade. The system also has a catheter having an inner surface and an outer surface, the catheter extending proximally of relative to the pump housing. The outer surface of the catheter is configured to contact blood when disposed within patient vasculature. The outer surface of the catheter comprises a heat transfer surface configured for cooling blood that comes in contact with the outer surface. The support system is operated to provide a temperature selected to cool the circulating blood in contact with the outer surface of the catheter to a temperature selected to reduce or prevent an effect of a cardiac episode.
1. A mechanical circulatory support system for a heart, the mechanical circulatory support system comprising:
a pump having a distal end and a proximal end, the pump comprising a rotor, the rotor having at least one blade;
a pump housing, the pump housing surrounding the at least one blade of the rotor;
a catheter having a distal end, a proximal end, an inner surface, and an outer surface, the catheter extending proximally relative to the pump housing, the outer surface of the catheter configured to contact blood when disposed within patient vasculature; and
a cooling element configured to cool the blood that comes in contact with the outer surface of the catheter, wherein the cooling element is formed as a lumen configured to receive a chilled solution.
2. The mechanical circulatory support system of claim 1 , wherein the cooling element is configured to cool the outer surface of the catheter.
3. The mechanical circulatory support system of claim 1 , wherein the cooling element extends within the catheter.
4. The mechanical circulatory support system of claim 1 , wherein the cooling element is configured to cool the inner surface of the catheter.
5. The mechanical circulatory support system of claim 4 , wherein cooling of the inner surface is configured to conduct thermal energy away from the outer surface of the catheter to cool the outer surface.
6. The mechanical circulatory support system of claim 5 , wherein the cooling element is configured to cool the outer surface of the catheter.
7. The mechanical circulatory support system of claim 1 , wherein the lumen is configured to extend along a length of the catheter twice.
8. The mechanical circulatory support system of claim 1 , wherein the lumen has a first proximal opening and a second proximal opening, the first proximal opening configured as an inlet for the chilled solution and the second proximal opening serving as an outlet for the chilled solution.
9. The mechanical circulatory support system of claim 8 , wherein a first flow portion along which the lumen extends is from the proximal end to the distal end, and a second flow portion along which the lumen extends is from the distal end to the proximal end.
10. The mechanical circulatory support system of claim 9 , wherein the first flow portion extends from the first proximal opening to the distal end of the catheter.
11. The mechanical circulatory support system of claim 9 , wherein the first flow portion accommodates a flow of the chilled solution from the proximal end of the catheter to the distal end of the catheter.
12. The mechanical circulatory support system of claim 9 , wherein the second flow portion extends from the distal end of the catheter to the second proximal opening.
13. The mechanical circulatory support system of claim 9 , wherein the second flow portion accommodates a flow of the chilled solution from the distal end of the catheter to the proximal end of the catheter.
14. The mechanical circulatory support system of claim 8 , wherein the chilled solution comprises a crystalloid fluid.
15. The mechanical circulatory support system of claim 14 , wherein the crystalloid fluid is a normal saline solution.
16. The mechanical circulatory support system of claim 1 , wherein the cooling element cools the blood that is in contact with the outer surface of the catheter to a systemic temperature.
17. The mechanical circulatory support system of claim 16 , wherein the systemic temperature is about 32 to about 33 degrees Celsius.
18. The mechanical circulatory support system of claim 1 , wherein the lumen is configured to deliver the chilled solution along a length of the catheter.