IP Library › Granted Patent US 12,740,859
Granted Patent B2
US 12,740,859 · App. 18/620,465 · Granted Sep 22, 2026

Holder and deployment system for prosthetic heart valves

Inventors: Da-Yu Chang (Irvine, CA); Hilda Z. Fann (Santa Ana, CA)
Assignee: Edwards Lifesciences Corporation
A61F2/2418A61F2/2427A61F2/243A61F2/2439A61F2210/00A61F2210/0014A61F2220/0075A61F2230/0069
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Quick Facts
Patent No.
US 12,740,859
App. No.
18/620,465
Granted
Sep 22, 2026
Kind
B2
Abstract

A holder for a hybrid heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The hybrid heart valve includes a non-expandable, non-compressible prosthetic valve and a self-expandable anchoring stent, thereby enabling attachment to the annulus without sutures. A first suture connects the holder to the valve and constricts an inflow end of the anchoring stent. A second suture connects the holder to the valve and extends down three holder legs to loop through fabric on the valve. Both sutures may loop over a single cutting well on the holder so that severing the first and second sutures at the single cutting well simultaneously releases the tension in the first suture, permitting the inflow end of the anchoring stent to expand, and disconnects the valve holder from the prosthetic heart valve.

Claims (14)

1 . A system for delivering a prosthetic heart valve to a native valve annulus, comprising:

a prosthetic heart valve including an annular support structure and a self-expandable anchoring stent together defining a flow orifice and an inflow end defining an inflow direction with an outflow direction opposite thereto, the self-expandable anchoring stent comprising a first end and a second end, the prosthetic heart valve having valve leaflets attached to the support structure and mounted to alternately open and close across the flow orifice;

a valve holder having a structure adapted to mate with a delivery handle; and

a connecting suture tied at first and second free ends to the valve holder and attaching the valve holder to the prosthetic heart valve at multiple locations, the connecting suture being routed over a single cutting well on the valve holder such that severing the connecting suture at the single cutting well detaches the valve holder from the prosthetic heart valve, the connecting suture extending around the anchoring stent in tension and constricting the second end of the self-expandable anchoring stent to a contracted state for delivery to the native valve annulus.

2 . The system of claim 1 , wherein the support structure is covered by a fabric and the valve holder has three legs that contact the fabric-covered support structure at three locations, and wherein the connecting suture passes circumferentially around the valve holder and threads through the fabric at the three locations.

3 . The system of claim 2 , wherein the support structure has three commissure posts projecting in the outflow direction and three cusps therebetween that arc in the inflow direction, wherein the three legs angle outward and in the inflow direction from a central hub of the valve holder to a terminal foot on each leg that contacts the prosthetic heart valve at one of the three cusps, and wherein the connecting suture is tied at the first and second free ends to the holder and in between passes circumferentially around the central hub of the holder and descends down each of the three legs to pass through the fabric at each of the three cusps.

4 . The system of claim 3 , wherein the connecting suture passes through two holes at the terminal foot of each of the three legs and threads through the fabric at each of the three cusps between the two holes, and wherein the connecting suture circles completely around each of the three legs between the hub and its respective terminal foot.

5 . The system of claim 3 , wherein the connecting suture is tied at the first and second free ends to one of the three legs of the holder.

6 . The system of claim 1 , wherein the self-expandable anchoring stent has the first end extending around the flow orifice and mounted to the prosthetic heart valve at an inflow end of the support structure, the anchoring stent having the second end projecting in the inflow direction away from the support structure, the second end transitioning between the contracted state and an expanded state.

7 . The system of claim 6 , wherein the connecting suture extends around the second end of the anchoring stent in tension and constricts the second end to the contracted state.

8 . The system of claim 7 , wherein the support structure is fabric-covered and further including an upper connecting suture tied at two free ends to the valve holder and passing through the fabric-covered support structure, wherein the connecting suture and the upper connecting suture pass over the single cutting well on the valve holder such that severing the connecting suture and the upper connecting suture both releases tension in the connecting suture to permit the second end to expand toward the expanded state and detaches the valve holder from the prosthetic heart valve.

9 . The system of claim 7 , wherein the anchoring stent has a fabric covering, and wherein the connecting suture passes through the fabric covering around the anchoring stent.

10 . The system of claim 7 , wherein the support structure has three commissure posts projecting in the outflow direction and three cusps therebetween that arc in the inflow direction, wherein the valve holder has three legs that angle outward and in the inflow direction from the central hub to contact the support structure at the three cusps, and wherein the connecting suture is tied at the first and second free ends to a terminal foot of one of the three legs.

11 . The system of claim 1 , wherein the support structure is non-expandable and non-collapsible.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 12, 2026
From: CHANG, DA-YU; FANN, HILDA Z.
To: EDWARDS LIFESCIENCES CORPORATION
Reel/Frame 074942/0611 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 11, 2026
From: CHANG, DA-YU; FANN, HILDA Z.
To: EDWARDS LIFESCIENCES CORPORATION
Reel/Frame 074929/0761 →
Continuity (6)
Continuation 17810182 · Jun 30, 2022
Continuation 16429651 · Jun 3, 2019
Continuation 15451203 · Mar 6, 2017
Continuation 14700007 · Apr 29, 2015
Provisional Application 61986761 · Apr 30, 2014
Related Publication 20240238086A1 · Jul 18, 2024
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