Apparatus and method for everting catheter for embryo transfer using transvaginal ultrasound
Everting balloon systems and methods for using the same with an alignment element for stability and anti-rotation of the everting balloon are disclosed herein. The systems can be configured to access and deliver instruments, media, or other catheters into bodily lumens and cavities. The alignment element can eliminate the potential for the everting membrane to become twisted or rotated which could impact access or the ability of the system to deliver materials. A compliance member can facilitate internal pressurization of the everting catheter system. An everting catheter system can be configured for use with transvaginal ultrasound and a lower profile speculum is described.
1 . A method for delivering matter into a uterine cavity, wherein the matter comprises a material that has an effect on reproduction, comprising:
everting a balloon in a cervical canal, wherein the balloon is attached to a first catheter, and wherein everting comprises pulling the first catheter distally through the cervical canal;
transporting a flexible tip guidance wire through the first catheter into the uterine cavity to direct a distal end of the everting balloon towards a targeted region, wherein the flexible tip guidance wire is advanced upon reduction of an internal pressure of the balloon;
transporting a second catheter holding the matter after access to the targeted region is reached; and
delivering the matter from the second catheter into the uterine cavity.
2 . The method of claim 1 , wherein the matter comprises a device.
3 . The method of claim 1 , wherein the matter comprises a hormone.
4 . The method of claim 1 , wherein the matter comprises an agent for affecting embryo implantation and/or adherence to the uterine endometrium.
5 . The method of claim 1 , wherein the matter comprises a therapeutic agent.
6 . The method of claim 1 , wherein the matter comprises a device and a hormone.