Implantable electrodes with remote power delivery for treating sleep apnea, and associated systems and methods
Implantable electrodes with power delivery wearable for treating sleep apnea, and associated systems and methods are disclosed herein. A representative system includes non-implantable signal generator worn by the patient and having an antenna that directs a mid-field RF power signal to an implanted electrode. The implanted electrode in turn directs a lower frequency signal to a neural target, for example, the patient's hypoglossal nerve. Representative signal generators can have the form of a mouthpiece, a collar or other wearable, and/or a skin-mounted patch.
1. A method of treating a patient, comprising:
providing power to
a first signal generator of a first percutaneously injectable device, the first percutaneously injectable device further including a first signal delivery device operably coupled to the first signal generator and positioned to deliver a first electrical signal to a hypoglossal nerve of the patient; and
a second signal generator of a second percutaneously injectable device, the second percutaneously injectable device further including a second signal delivery device operably coupled to the second signal generator and positioned to deliver a second electrical signal to an ansa cervicalis nerve of the patient;
delivering, via the first signal delivery device, the first electrical signal to the patient's hypoglossal nerve; and
delivering, via the second signal delivery device, the second electrical signal to the patient's ansa cervicalis nerve.
2. The method of claim 1 wherein providing the power includes:
wirelessly providing a first power signal to the first signal generator; and
wirelessly providing a second power signal to the second signal generator.
3. The method of claim 1 wherein providing the power includes:
providing a first power signal to the first signal generator from a first charge storage device of the first percutaneously injectable device; and
providing a second power signal to the second signal generator from a second charge storage device of the second percutaneously injectable device.
4. The method of claim 3 wherein the first charge storage device and/or the second charge storage device have a total charge storage capacity of no more than 5 minutes.
5. The method of claim 1 , further comprising:
percutaneously injecting the first percutaneously injectable device such that the first signal delivery device is positioned to deliver the first electrical signal to the patient's hypoglossal nerve; and
percutaneously injecting the second percutaneously injectable device such that the second signal delivery device is positioned to deliver the second electrical signal to the patient's ansa cervicalis nerve.
6. The method of claim 1 wherein providing the power includes transmitting one or more power signals, via one or more external power transmission devices, a first power receiving device of the first percutaneously injectable device and/or to a second power receiving device of the second percutaneously injectable device.
7. The method of claim 6 wherein transmitting the one or more power signals includes:
transmitting, via a first external power transmission device, a first power signal to the first power receiving device; and
transmitting, via a second external power transmission device, a second power signal to the second power receiving device.
8. The method of claim 1 wherein providing the power includes providing power via an inductive coil or an RF antenna.
9. The method of claim 1 wherein:
the first signal delivery device includes a first lead body carrying one or more first electrodes; and
the second signal delivery device includes a second lead body carrying one or more second electrodes.
10. A method of treating a breathing disorder in a patient, comprising:
providing power to
a first signal generator of a first percutaneously injectable device, the first percutaneously injectable device further including a first signal delivery device operably coupled to the first signal generator and positioned to deliver a first electrical signal to a hypoglossal nerve of the patient; and
a second signal generator of a second percutaneously injectable device, the second percutaneously injectable device further including a second signal delivery device operably coupled to the second signal generator and positioned to deliver a second electrical signal to an ansa cervicalis nerve of the patient; and
in response to an indication that the patient is experiencing apnea and/or hypopnea
delivering, via the first signal delivery device, the first electrical signal to the patient's hypoglossal nerve; and/or
delivering, via the second signal delivery device, the second electrical signal to the patient's ansa cervicalis nerve.
11. The method of claim 10 wherein providing the power includes:
transmitting, via a first power transmission device, a first power signal to the first signal generator via a first power receiving device of the first percutaneously injectable device; and
transmitting, via a second power transmission device, a second power signal to the second signal generator via a second power receiving device of the second percutaneously injectable device.
12. The method of claim 10 wherein providing the power includes providing power via one or more inductive coils and/or one or more RF antennas.
13. The method of claim 10 wherein providing the power includes:
providing a first power signal to the first signal generator via a first charge storage device of the first percutaneously injectable device; and
providing a second power signal to the second signal generator via a second charge storage device of the second percutaneously injectable device.
14. The method of claim 13 wherein the first charge storage device and/or the second charge storage device have a total charge storage capacity of no more than 5 minutes.
15. The method of claim 10 wherein the indication includes information associated with the patient's respiratory rate and/or audio signals associated with one or more apnea and/or hypopnea events.
16. The method of claim 10 wherein the indication includes information obtained via a flow sensor, a pulse oximeter, a photoplethysmography sensor, and/or a patient orientation sensor.
17. The method of claim 10 , further comprising:
percutaneously injecting the first percutaneously injectable device such that the first signal delivery device is positioned to deliver the first electrical signal to the patient's hypoglossal nerve; and
percutaneously injecting the second percutaneously injectable device such that the second signal delivery device is positioned to deliver the second electrical signal to the patient's ansa cervicalis nerve.