IP Library › Granted Patent US 12,601,805
Granted Patent B2
US 12,601,805 · App. 18/646,989 · Granted Apr 14, 2026

Dynamic contrast-enhanced magnetic resonance imaging reconstruction method and apparatus, and magnetic resonance imaging system

Inventor: Cai Xia Fu (Shanghai, CN)
Assignee: Siemens Healthineers AG
G01R33/5601G01R33/5608G01R33/56308
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Quick Facts
Patent No.
US 12,601,805
App. No.
18/646,989
Granted
Apr 14, 2026
Kind
B2
Abstract

A dynamic contrast-enhanced MRI reconstruction method may include: when preparing to inject a contrast agent and during injection thereof, using a DCE-MRI sequence to scan an imaging target, and using a high temporal resolution scanning parameter value pre-inputted by a user to acquire K-space data of each phase with high temporal resolution; based on the acquired K-space data of each phase with high temporal resolution, reconstructing an image of each phase with high temporal resolution; based on a low temporal resolution reconstruction parameter value pre-inputted by the user, subjecting adjacent K-space data of multiple phases with high temporal resolution to summing and averaging in a complex field, and subjecting K-space data obtained after averaging to image reconstruction, to obtain an image of each phase with low temporal resolution. Advantageously, images with high and low temporal resolution can be obtained simultaneously with just a single DCE-MRI scan.

Claims (45)

1 . A dynamic contrast-enhanced magnetic resonance imaging reconstruction method, the method comprising:

acquiring, using a dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) sequence to scan an imaging target, and a received high temporal resolution scanning parameter value, K-space data of each phase with high temporal resolution in preparation of injection of a contrast agent and during injection thereof;

reconstructing, based on the acquired K-space data of each phase with high temporal resolution, an image of each phase with high temporal resolution; and

performing, based on a received low temporal resolution reconstruction parameter value and the high temporal resolution scanning parameter value used when acquiring K-space data of each phase with high temporal resolution:

summing and averaging, in a complex field, of adjacent K-space data of multiple phases with high temporal resolution; and

image reconstruction of K-space data obtained after averaging to obtain an image of each phase with low temporal resolution.

2 . The method as claimed in claim 1 , wherein the acquisition of the K-space data of each phase with high temporal resolution is based on:

a preset K-space data filling method that includes a Cartesian filling, a radial filling, or spiral filling; and

an acceleration method that includes a half-Fourier acquisition, a parallel acquisition, a multi-layer simultaneous acquisition, and/or compressed sensing sparse acquisition.

3 . The method as claimed in claim 2 , further comprising determining a reconstruction method according to the filling method and acceleration method used when acquiring K-space data of each phase with high temporal resolution, wherein:

reconstructing the image of each phase with high temporal resolution is based on the determined reconstruction method; and

the performing image reconstruction on the K-space data obtained after averaging is based on the determined reconstruction.

4 . The method as claimed in claim 1 , wherein summing and averaging, in the complex field, adjacent K-space data of multiple phases with high temporal resolution to summing and then averaging in a complex field is performed after phase correction and motion registration.

5 . The method as claimed in claim 1 , wherein the high temporal resolution scanning parameter value comprises: an acquisition time interval of two adjacent phases when acquiring K-space data with high temporal resolution, the acquisition time interval: remaining unchanged throughout acquisition of the K-space data with high temporal resolution, or increasing as a delay time after contrast agent injection increases throughout the acquisition of the K-space data with high temporal resolution.

6 . The method as claimed in claim 1 , wherein the low temporal resolution reconstruction parameter value comprises a time interval of two adjacent phases of a reconstructed low temporal resolution image, the time interval of two adjacent phases of the reconstructed low temporal resolution image: being constant in all reconstructed low temporal resolution phases, or increasing as a delay time after contrast agent injection increases.

7 . The method as claimed in claim 1 , wherein is high temporal resolution scanning parameter value is predetermined prior to acquisition of the K-space data.

8 . The method as claimed in claim 1 , wherein is high temporal resolution scanning parameter value is pre-inputted by a user.

9 . A non-transitory computer-readable storage medium with an executable program stored thereon, that when executed, instructs a processor to perform the method of claim 1 .

10 . A dynamic contrast-enhanced magnetic resonance imaging reconstruction apparatus, comprising:

a K-space data acquisition module configured to, in preparation to inject a contrast agent and/or during injection thereof:

scan an imaging target using a dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) sequence to scan an imaging target, and

acquire K-space data of each phase with high temporal resolution using a high temporal resolution scanning parameter value;

a high temporal resolution image reconstruction module configured to reconstruct an image of each phase with high temporal resolution, based on the acquired K-space data of each phase with high temporal resolution; and

a low temporal resolution image reconstruction module configured to:

in a complex field, sum and then average adjacent K-space data of multiple phases with high temporal resolution, based on: a low temporal resolution reconstruction parameter value, and the high temporal resolution scanning parameter value used when acquiring K-space data of each phase with high temporal resolution; and

perform image reconstruction to K-space data obtained after averaging to obtain an image of each phase with low temporal resolution.

11 . The apparatus as claimed in claim 10 , wherein, to acquire K-space data of each phase with high temporal resolution, the K-space data acquisition module is further configured to use:

a preset K-space data filling method that includes a Cartesian filling, or a radial filling, or a spiral filling, and

an acceleration method that includes a half-Fourier acquisition, a parallel acquisition, a multi-layer simultaneous acquisition, and/or a compressed sensing sparse acquisition.

12 . The apparatus as claimed in claim 11 , wherein:

the reconstructing the image of each phase with high temporal resolution by the high temporal resolution image reconstruction module, comprises: determining a reconstruction method according to the filling method and acceleration method used when acquiring K-space data of each phase with high temporal resolution, and using the determined reconstruction method to reconstruct an image of each phase with high temporal resolution; and

performing, by the low temporal resolution image reconstruction module, image reconstruction on the K-space data obtained after averaging comprises: determining a reconstruction method according to the filling method and acceleration method used when acquiring K-space data of each phase with high temporal resolution, and using the determined reconstruction method to subject K-space data obtained after averaging to image reconstruction.

13 . The apparatus as claimed in claim 10 , wherein the low temporal resolution image reconstruction module is configured to sum and average the adjacent K-space data of multiple phases with high temporal resolution after phase correction and motion registration.

14 . The apparatus as claimed in claim 10 , wherein the high temporal resolution scanning parameter value comprises: an acquisition time interval of two adjacent phases when acquiring K-space data with high temporal resolution, the acquisition time interval of two adjacent phases remaining unchanged throughout the period of acquiring K-space data with high temporal resolution or increasing as a delay time after contrast agent injection increases throughout acquisition of the K-space data with high temporal resolution.

15 . The apparatus as claimed in claim 10 , wherein the low temporal resolution reconstruction parameter value comprises a time interval of two adjacent phases of a reconstructed low temporal resolution image, the time interval of two adjacent phases of the reconstructed low temporal resolution image remaining constant in all reconstructed low temporal resolution phases or increasing as a delay time after contrast agent injection increases.

16 . A magnetic resonance (MR) imaging system comprising: the dynamic contrast-enhanced magnetic resonance imaging reconstruction apparatus as claimed in claim 10 .

17 . The system as claimed in claim 16 , further comprising a MR scanner.

18 . A dynamic contrast-enhanced magnetic resonance imaging reconstruction apparatus, comprising:

one or more processors; and

memory storing instructions that, when executed by the one or more processors, cause the apparatus to:

acquire, using a dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) sequence to scan an imaging target, and a received high temporal resolution scanning parameter value, K-space data of each phase with high temporal resolution in preparation of injection of a contrast agent and during injection thereof;

reconstruct, based on the acquired K-space data of each phase with high temporal resolution, an image of each phase with high temporal resolution; and

based on a received low temporal resolution reconstruction parameter value and the high temporal resolution scanning parameter value used when acquiring K-space data of each phase with high temporal resolution:

sum and average, in a complex field, of adjacent K-space data of multiple phases with high temporal resolution; and

perform image reconstruction of K-space data obtained after averaging to obtain an image of each phase with low temporal resolution.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 17, 2024
From: FU, CAI XIA
To: SIEMENS SHENZHEN MAGNETIC RESONANCE LTD.
Reel/Frame 069612/0876 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 17, 2024
From: SIEMENS SHENZHEN MAGNETIC RESONANCE LTD.
To: SIEMENS HEALTHINEERS AG
Reel/Frame 069613/0130 →
Priority Claims (1)
CN 202310488314.X · Apr 28, 2023 · national
Continuity (1)
Related Publication 20240361410A1 · Oct 31, 2024
References Cited (3)
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US 11016159B2 · Hu · 2021 [cited by examiner]
US 11079455B2 · Okell · 2021 [cited by examiner]