SINGLE-USE NEUROTOXIN FORMULATIONS AND PACKAGING
Disclosed herein are systems and devices for use with neurotoxin formulations.
1 ) A vessel for neurotoxin formulations, wherein said vessel contains between 100% and 110% of the amount of neurotoxin intended to be administered to a patient in a single fixed-site fixed-dose treatment session.
2 ) The vessel of claim 1 , wherein said treatment session comprises a migraine treatment.
3 ) The vessel of claim 2 , wherein said migraine comprises chronic migraine.
4 ) The vessel of claim 3 , wherein said vessel contains between 145 and 200 units of neurotoxin.
5 ) The vessel of claim 4 , wherein said neurotoxin comprises a Clostridial toxin.
6 ) The vessel of claim 5 , wherein said Clostridial toxin comprises a botulinum toxin.
7 ) The vessel of claim 6 , wherein said botulinum toxin comprises botulinum type A, B, C, D, E, or F.
8 ) The vessel of claim 7 , wherein said botulinum toxin comprises botulinum type A.
9 ) The vessel of claim 7 , wherein said botulinum toxin comprises botulinum type B.
10 ) The vessel of claim 7 , wherein said botulinum toxin comprises botulinum type C.
11 ) The vessel of claim 7 , wherein said botulinum toxin comprises botulinum type E.
12 ) The vessel of claim 7 , wherein said botulinum toxin comprises botulinum type F.
13 ) The vessel of claim 8 , wherein said vessel contains 145 units of botulinum type A.
14 ) The vessel of claim 8 , wherein said vessel contains 150 units of botulinum type A.
15 ) The vessel of claim 8 , wherein said vessel contains 155 units of botulinum type A.
16 ) The vessel of claim 8 , wherein said vessel contains 160 units of botulinum type A.
17 ) The vessel of claim 8 , wherein said vessel contains 165 units of botulinum type A.
18 ) The vessel of claim 8 , wherein said vessel contains 170 units of botulinum type A.
19 ) The vessel of claim 8 , wherein said vessel contains 175 units of botulinum type A.
20 ) The vessel of claim 8 , wherein said vessel contains 180 units of botulinum type A.
21 ) The vessel of claim 8 , wherein said vessel contains 185 units of botulinum type A.
22 ) The vessel of claim 8 , wherein said vessel contains 190 units of botulinum type A.
23 ) The vessel of claim 8 , wherein said vessel contains 195 units of botulinum type A.
24 ) The vessel of claim 8 , wherein said vessel contains 200 units of botulinum type A.
25 ) The vessel of claim 1 , wherein said vessel further comprises a stopper.
26 ) The stopper of claim 25 , wherein said stopper is color-coded for a specific treatment.
27 ) The color-coded stopper of claim 26 , wherein said color comprises at least one of red, orange, yellow, green, blue, indigo, or violet, or combinations thereof.
28 ) The vessel of claim 1 , wherein said vessel is color-coded for a specific treatment.
29 ) The color-coded vessel of claim 28 , wherein said color comprises at least one of red, orange, yellow, green, blue, indigo, or violet, or combinations thereof.
30 ) A prefilled diluent syringe, wherein said prefilled diluent syringe contains between 100% and 110% of the amount of diluent intended to be used to dilute an amount of neurotoxin intended to be administered to a patient in a single fixed-site fixed-dose treatment session.
31 ) The prefilled diluent syringe of claim 30 , wherein said diluent comprises saline.
32 ) The prefilled diluent syringe of claim 31 , wherein said syringe is color-coded for a specific treatment.
33 ) The color-coded syringe of claim 32 , wherein said color comprises at least one of red, orange, yellow, green, blue, indigo, or violet, or combinations thereof.
34 ) A kit comprising:
a vessel for a neurotoxin formulation, wherein said vessel contains between 100% and 110% of the amount of neurotoxin intended to be administered to a patient in a single fixed-site fixed-dose treatment session; and
a prefilled diluent syringe, wherein said prefilled diluent syringe contains between 100% and 110% of the amount of diluent intended to be used to dilute an amount of neurotoxin intended to be administered to a patient in a single fixed-site fixed-dose treatment session.
35 ) The kit of claim 34 , wherein said treatment session comprises a migraine treatment.
36 ) The kit of claim 35 , wherein said migraine comprises chronic migraine.
37 ) The kit of claim 34 , wherein said vessel contains between 145 and 200 units of neurotoxin.
38 ) The kit of claim 37 , wherein said neurotoxin comprises a Clostridial toxin.
39 ) The kit of claim 38 , wherein said Clostridial toxin comprises a botulinum toxin.
40 ) The kit of claim 39 , wherein said botulinum toxin comprises botulinum type A, B, C, D, E, or F.
41 ) The kit of claim 40 , wherein said diluent comprises saline.
42 ) The kit of claim of claim 41 , wherein said vessel is color-coded for a specific treatment.
43 ) The kit of claim 42 , wherein said color comprises at least one of red, orange, yellow, green, blue, indigo, or violet, or combinations thereof.
44 ) The kit of claim 43 , wherein said vessel comprises a stopper.
45 ) The kit of claim 44 , wherein said stopper is color-coded for a specific treatment.
46 ) The kit of claim 45 , wherein said color comprises at least one of red, orange, yellow, green, blue, indigo, or violet, or combinations thereof.
47 ) The kit of claim 34 , wherein said vessel is comprised of a hydrophobic material.
48 ) The kit of claim 34 , wherein said vessel comprises a hydrophobic coating on its interior surface.
49 ) The kit of claim 48 , wherein said hydrophobic coating comprises Polytetrafluoroethylene (PTFE).
50 ). The kit of claim 44 , wherein said stopper is comprised of a hydrophobic material.
51 ) The kit of claim 44 , wherein said stopper comprises a hydrophobic coating on its outer surface.
52 ) The kit of claim 50 , wherein said hydrophobic material comprises Polytetrafluoroethylene (PTFE).
53 ) The kit of claim 51 , wherein said hydrophobic coating comprises Polytetrafluoroethylene (PTFE).
54 ) The kit of claim 34 , wherein said vessel comprises a bottom interior that is not parallel to the bottom exterior.
55 ) The kit of claim 54 , wherein said vessel bottom interior is sloped.
56 ) The kit of claim 54 , wherein said vessel bottom interior is concave.
57 ) The vessel of claim 1 , wherein said vessel comprises a bottom interior that is not parallel to the bottom exterior.
58 ) The vessel of claim 57 , wherein said vessel bottom interior is sloped.
59 ) The vessel of claim 57 , wherein said vessel bottom interior is concave.