IP Library › Patent Application 18821773
Patent Application
App. No. 18/821,773

POLYMER PARTICLES

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Quick Facts
Patent No.
US None
App. No.
18/821,773
Abstract

Polymer particle embolics and methods of making same are described. The particle embolics can be used as embolization agents.

Claims (16)

1 . A polymer particle comprising:

at least one derivatized macromer at a concentration of between about 15% w/w and about 50% w/w; and

at least one monomer that is not n-isopropyl acrylamide.

2 . The polymer particle of claim 1 , wherein the macromer is a poly(ethylene glycol) macromer, poly(propylene glycol) macromer, poly(tetramethylene oxide) macromer, or a combination thereof.

3 . The polymer particle of claim 2 , wherein the at least one derivatized poly(ethylene glycol) macromer is poly(ethylene glycol) diacrylamide, poly(ethylene glycol) diacrylate, poly(ethylene glycol) dimethacrylate, poly(ethylene glycol) dimethacrylamide, or a combination thereof.

4 . The polymer particle of claim 2 , wherein the at least one derivatized poly(ethylene glycol) macromer is poly(ethylene glycol) diacrylamide 10,000.

5 . The polymer particle of claim 1 , wherein the polymer particle has a diameter between about 40 μm and about 1,200 μm.

6 . The polymer particle of claim 1 , further comprising at least one monomer.

7 . The polymer particle of claim 6 , wherein the at least one monomer includes a functional group, wherein the functional group is acrylate, acrylamide, methacrylate, or methacrylamide.

8 . The polymer particle of claim 6 , wherein the at least one monomer is glycerol monomethacrylate, amino ethyl methacrylate, 3-sulfopropyl acrylate, amino propyl methacrylamide, or a combination thereof.

9 . The polymer particle of claim 8 , wherein the at least one monomer is glycerol monomethacrylate at a concentration of about 68% w/w.

10 . The polymer particle of claim 8 , wherein the at least one monomer is 3-sulfopropyl acrylate at a concentration of about 59% w/w.

11 . The polymer particle of claim 8 , wherein the at least one monomer is amino propyl methacrylamide at a concentration of about 1% w/w.

12 . The polymer particle of claim 8 , wherein the at least one monomer is amino ethyl methacrylate at a concentration of about 3% w/w.

13 . A kit comprising a polymer particle of claim 1 .

14 . An injectable therapeutic composition comprising a polymer particle of claim 1 .

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 30, 2024
From: PLOTKIN, STEVE; CRUISE, GREGORY M.; KEELEY, EDWARD MICHAEL; YU, RENEE; HARRIS, CLAYTON
To: MICROVENTION, INC.
Reel/Frame 068456/0320 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 30, 2024
From: MICROVENTION, INC.
To: TERUMO CORPORATION
Reel/Frame 068456/0370 →