IP Library Patent Application 18944565
Patent Application
App. No. 18/944,565

SYSTEMS AND METHODS TO PROCESS ELECTRONIC IMAGES TO PROVIDE BLUR ROBUSTNESS

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Patent No.
US None
App. No.
18/944,565
Abstract

A computer-implemented method for processing electronic medical images, the method including receiving a plurality of electronic medical images of a medical specimen. Each of the plurality of electronic medical images may be divided into a plurality of tiles. A plurality of sets of matching tiles may be determined, the tiles within each set corresponding to a given region of a plurality of regions of the medical specimen. For each tile of the plurality of sets of matching tiles, a blur score may be determined corresponding to a level of image blur of the tile. For each set of matching tiles, a tile may be determined with the blur score indicating the lowest level of blur. A composite electronic medical image, comprising a plurality of tiles from each set of matching tiles with the blur score indicating the lowest level of blur, may be determined and provided for display.

Claims (62)

1 . A computer-implemented method for processing electronic medical images, the method comprising:

receiving a plurality of electronic medical images of a medical specimen;

dividing each of the plurality of electronic medical images into a plurality of tiles, each tile of the plurality of tiles being of a predetermined size;

determining a plurality of sets of matching tiles, the tiles within each set corresponding to a given region of a plurality of regions of the medical specimen;

for each tile of the plurality of sets of matching tiles, determining a blur score corresponding to a level of image blur of the tile;

determining whether each tile within a first set of matching tiles has a blur score beyond a threshold value;

upon determining that each tile within a first set of matching tiles has a blur score beyond a threshold value, applying at least one generative model to at least one tile of the first set of matching tiles to generate a higher resolution tile;

for each set of the plurality of sets of matching tiles, determining a tile with the blur score indicating a lowest level of blur;

determining a composite electronic medical image, the composite electronic medical image comprising a plurality of tiles, from each set of matching tiles, with the blur score indicating the lowest level of blur; and

providing the composite electronic medical image for display.

2 . The computer-implemented method of claim 1 , further comprising:

determining if a predetermined threshold of tiles in a given location have inadequate blur scores; and

upon determining that the predetermined threshold of tiles in a given location have inadequate blur scores, ordering a rescan of the corresponding medical image.

3 . The computer-implemented method of claim 1 , wherein determining a blur score further comprises:

determining whether each tile within the first set of matching tiles has a blur score beyond a second threshold value; and

upon determining whether each tile within the first set of matching tiles has a blur score beyond the second threshold value, indicating or storing an indication that a rescan of the medical specimen is needed.

4 . The computer-implemented method of claim 1 , wherein the blur score is output by a machine learning model that receives the plurality of tiles, the machine learning model applying, to the tiles, one or more weights, biases, and/or layers, and outputting a blur score for each tile.

5 . The computer-implemented method of claim 1 , wherein determining a composite electronic medical image is performed using a machine learning model.

6 . The computer-implemented method of claim 1 , wherein the blur score is determined by applying a wavelet transform for each tile of the plurality of sets of matching tiles.

7 . The computer-implemented method of claim 1 , wherein the blur score is determined by applying a Discrete Fourier Transform to each tile of the plurality of sets of matching tiles.

8 . The computer-implemented method of claim 1 , further comprising:

providing at least one corresponding indication of which tiles of the composite electronic medical image had the at least one generative model applied.

9 . A system for processing electronic digital medical images, the system comprising:

at least one memory storing instructions; and

at least one processor configured to execute the instructions to perform operations comprising:

receiving a plurality of electronic medical images of a medical specimen;

dividing each of the plurality of electronic medical images into a plurality of tiles, each tile of the plurality of tiles being of a predetermined size;

determining a plurality of sets of matching tiles, the tiles within each set corresponding to a given region of a plurality of regions of the medical specimen;

for each tile of the plurality of sets of matching tiles, determining a blur score corresponding to a level of image blur of the tile;

determining whether each tile within a first set of matching tiles has a blur score beyond a threshold value;

upon determining that each tile within a first set of matching tiles has a blur score beyond a threshold value, applying at least one generative model to at least one tile of the first set of matching tiles to generate a higher resolution tile;

for each set of the plurality of sets of matching tiles, determining a tile with the blur score indicating a lowest level of blur;

determining a composite electronic medical image, the composite electronic medical image comprising a plurality of tiles, from each set of matching tiles, with the blur score indicating the lowest level of blur; and

providing the composite electronic medical image for display.

10 . The system of claim 9 , further comprising:

determining if a predetermined threshold of tiles in a given location have inadequate blur scores; and

upon determining that the predetermined threshold of tiles in a given location have inadequate blur scores, ordering a rescan of the corresponding medical image.

11 . The system of claim 9 , wherein determining a blur score further comprises:

determining whether each tile within the first set of matching tiles has a blur score beyond a second threshold value; and

upon determining whether each tile within the first set of matching tiles has a blur score beyond the second threshold value, indicating or storing an indication that a rescan of the medical specimen is needed.

12 . The system of claim 9 , wherein the blur score is output by a machine learning model that receives the plurality of tiles, the machine learning model applying to the tiles, one or more weights, biases, and/or layers, and outputting a blur score for each tile.

13 . The system of claim 9 , wherein determining a composite electronic medical image is performed using a machine learning model.

14 . The system of claim 9 , wherein the blur score is determined by applying a wavelet transform for each tile of the plurality of sets of matching tiles.

15 . The system of claim 9 , wherein the blur score is determined by applying a Discrete Fourier Transform to each tile of the plurality of sets of matching tiles.

16 . The system of claim 9 , further comprising:

providing at least one corresponding indication of which tiles of the composite electronic medical image had the at least one generative model applied.

17 . A non-transitory computer-readable medium storing instructions that, when executed by a processor, perform operations processing electronic digital medical images, the operations comprising:

receiving a plurality of electronic medical images of a medical specimen;

dividing each of the plurality of electronic medical images into a plurality of tiles, each tile of the plurality of tiles being of a predetermined size;

determining a plurality of sets of matching tiles, the tiles within each set corresponding to a given region of a plurality of regions of the medical specimen;

for each tile of the plurality of sets of matching tiles, determining a blur score corresponding to a level of image blur of the tile;

determining whether each tile within a first set of matching tiles has a blur score beyond a threshold value;

upon determining that each tile within a first set of matching tiles has a blur score beyond a threshold value, applying at least one generative model to at least one tile of the first set of matching tiles to generate a higher resolution tile;

for each set of the plurality of sets of matching tiles, determining a tile with the blur score indicating a lowest level of blur;

determining a composite electronic medical image, the composite electronic medical image comprising a plurality of tiles, from each set of matching tiles, with the blur score indicating the lowest level of blur; and

providing the composite electronic medical image for display.

18 . The computer-readable medium of claim 17 , further comprising:

determining if a predetermined threshold of tiles in a given location have inadequate blur scores; and

upon determining that the predetermined threshold of tiles in a given location have inadequate blur scores, ordering a rescan of the corresponding medical image.

19 . The computer-readable medium of claim 17 , wherein the blur score is output by a machine learning model that receives the plurality of tiles, the machine learning model applying to the tiles, one or more weights, biases, and/or layers, and outputting a blur score for each tile.

20 . The computer-readable medium of claim 17 , the operations further comprising:

providing at least one corresponding indication of which tiles of the composite electronic medical image had the at least one generative model applied.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded May 14, 2026
From: ARES CAPITAL CORPORATION, AS COLLATERAL AGENT
To: PAIGE.AI, INC.
Reel/Frame 075589/0752 →
SECURITY INTEREST Recorded Oct 21, 2025
From: PAIGE.AI, INC.
To: ARES CAPITAL CORPORATION, AS COLLATERAL AGENT
Reel/Frame 073216/0876 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 10, 2024
From: CEBALLOS LENTINI, RODRIGO; KANAN, CHRISTOPHER
To: PAIGE.AI, INC.
Reel/Frame 069539/0778 →