IP Library › Patent Application 19016496
Patent Application
App. No. 19/016,496

CRYSTALLINE PHASES OF 5,6-DICHLORO-2-(ISOPROPYLAMINO)-(1 BETA-L-RIBOFURANOSYL)1H-BENZIMIDAZOLE

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Quick Facts
Patent No.
US None
App. No.
19/016,496
Abstract

The invention relates to novel crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-(.beta.-L-ribofuranosyl)-1H-benzimidazo-le (Maribavir), pharmaceutical compositions thereof and their use in medical therapy.

Claims (2)

1 . A crystalline solvate of 5,6-dichloro-2-(isopropylamino)-1-(β-L-ribofuranosyl)-1H-benzimidazole, including a stoichiometric ratio of an organic solvent within a cavity of the crystal lattice, said solvent being selected from the group of: methanol, acetonitrile, ethyl acetate, diethylether, n-butylacetate, or 1-propanol, or mixtures thereof.

2 . Crystalline Form VI of 5,6-dichloro-2-(isopropylamino)-1-(β-L-ribofuranosyl)-1H-benzimidazole, wherein said compound has unit cell parameters a=b=9.2825Å, c=41.602Å, and P4 1 2 1 2 space group (recorded at 296 K).

Assignments (4)
CHANGE OF NAME Recorded Apr 17, 2026
From: VIROPHARMA INCORPORATED
To: SHIRE VIROPHARMA INCORPORATED
Reel/Frame 075459/0121 →
CHANGE OF NAME Recorded Apr 17, 2026
From: SHIRE VIROPHARMA INCORPORATED
To: SHIRE VIROPHARMA LLC
Reel/Frame 075425/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 17, 2026
From: COQUEREL, GERALD; LEVILAIN, GUILLAUME; PETIT, MARIE-NOELLE; COSTE-LECONTE, SERVANTE
To: VIROPHARMA INCORPORATED
Reel/Frame 074402/0727 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 17, 2026
From: SHIRE VIROPHARMA LLC
To: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Reel/Frame 074402/0915 →